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| 1 | Gastroenterologist perceptions of faecal microbiota transplantation显示文摘AIM: To explore gastroenterologist perceptions towards and experience with faecal microbiota transplantation(FMT).METHODS: A questionnaire survey consisting of 17 questions was created to assess gastroenterologists' attitude towards and experience with FMT. This was anonymously distributed in hard copy format amongst attendees at gastroenterology meetings in Australia between October 2013 and April 2014. Basic descriptive statistical analyses were performed.RESULTS: Fifty-two clinicians participated. Twenty one percent had previously referred patients for FMT,8% more than once. Ninety percent would refer patients with Clostridium difficile infection(CDI) for FMT if easily available,37% for ulcerative colitis,13% for Crohn's disease and 6% for irritable bowel syndrome. Six percent would not refer any indication,including recurrent CDI. Eighty-six percent would enroll patients in FMT clinical trials. Thirty-seven percent considered the optimal mode of FMT administration transcolonoscopic,17% nasoduodenal,13% enema and 8% oral capsule. The greatest concerns regarding FMT were: 42% lack of evidence,12% infection risk,10% non infectious adverse effects/lack of safety data,10% aesthetic,10% lack of efficacy,4% disease exacerbation,and 2% inappropriate use; 6% had no concerns. Seventy seven percent believed there is a lack of accessibility while 52% had an interest in learning how to provide FMT. Only 6% offered FMT at their institution.CONCLUSION: Despite general enthusiasm,most gastroenterologists have limited experience with,or access to,FMT. The greatest concerns were lack of supportive evidence and safety issues. However a significant proportion would refer indications other than CDI for FMT despite insufficient evidence. These data provide guidance on where education and training are required. | Sudarshan Paramsothy Alissa J Walsh Thomas Borody Douglas Samuel Johan van den Bogaerde Rupert WL Leong Susan Connor Watson Ng Hazel M Mitchell Nadeem O Kaakoush Michael A Kamm | 2015 | World Journal of Gastroenterology2015，21，38： | 5 |
| 2 | Reuse of liver grafts following the brain death of the initial recipient显示文摘AIM: To determine if there is a reasonable prospect of success of a re-use liver transplantation.METHODS: We systematically searched for reports of liver graft re-use using electronic searches of PubMed and Web of Knowledge. We performed hand searches of references lists of articles reporting re-use of grafts.RESULTS: A systematic review of the literature reveals 28 liver transplantations using previously transplanted grafts. First and second recipients ranged in age from 4 to 72 years and 29 to 62 years respectively. Liver disease in the first recipient was varied including 5(18%) patients with fulminant liver failure who died subsequently of cerebral edema. The second transplanta-tion was performed after a median interval of 5 d(one day-13 years). Viral hepatitis was present in 3(11%) of the initial recipients and in 8(29%) of final recipients. Hepatocellular carcinoma was present in 6(21%) of the final recipients. Early survival after the final transplantation was 93%, whereas long-term survival was 78% with a mean follow-up of 23.3(3-120) mo.CONCLUSION: Outcomes of transplantation using previously transplanted grafts in this select population are similar to those seen with conventional grafts. | Hideaki Tanaka Vivian C McAlister Mark A Levstik Cameron N Ghent Paul J Marotta Douglas Quan William J Wall | 2014 | World Journal of Hepatology2014，6，6： | 3 |
| 3 | Label-retaining liver cancer cells are relatively resistant to sorafenib显示文摘 | Hong-Wu Xin Chenwi M Ambe Danielle M Hari Gordon W Wiegand Tyler C Miller Jin-Qiu Chen Andrew J Anderson Satyajit Ray John E Mullinax Tomotake Koizumi Russell C Langan Douglas Burka Michelle A Herrmann Paul K Goldsmith Alexander Stojadinovic Udo Rudloff S | 2013 | Gut2013，，12： | 2 |
| 4 | Predictors of progression in Barrett’s esophagus II: baseline 17p (p53) loss of heterozygosity identifies a patient subset at increased risk for neoplastic progression显示文摘 | Brian J Reid Laura J Prevo Patricia C Galipeau Carissa A Sanchez Gary Longton Douglas S Levine Patricia L Blount Peter S Rabinovitch | 2001 | The American Journal of Gastroenterology2001，，10： | 2 |
| 5 | Laser in situ keratomileusis for myopia and astigmatism: safety and efficacy显示文摘 | Alan Sugar Christopher J Rapuano William W Culbertson David Huang Gary A Varley Peter J Agapitos Vincent P de Luise Douglas D Koch | 2002 | Ophthalmology2002，，1： | 2 |
| 6 | The midseason crash in aphid populations:why and how does it occur显示文摘 | Karley A J Parker WE Pitchford JW Douglas AE | | 0，，： | 1 |
| 7 | No Significant Association of 14 Candidate Genes With Schizophrenia in a Large European Ancestry Sample: Implications for Psychiatric Genetics显示文摘 | Sanders Alan R Duan Jubao Levinson Douglas F Shi Jianxin He Deli Hou Cuiping Burrell Gregory J Rice John P Nertney Deborah A Olincy Ann Rozic Pablo Vinogradov Sophia Buccola Nancy G Mowry Bryan J Freedman Robert Amin Farooq Black Donald W | 2008 | The American Journal of Psychiatry2008，，4： | 1 |
| 8 | Modification of the Phase Stability of Polymer Blends by Fillers显示文摘 | Karim A Liu D W Douglas J F | 2000 | Poly mer2000，41，： | 1 |
| 9 | Habitat corridors function as both drift fences and movement conduits for dispersing flies显示文摘 | JOANNA H F DOUGLAS J L JEROME A H | 2005 | Oecologia2005，143，4： | 1 |
| 10 | Spinodal dewetting of thin polymer films 显示文摘 | Xie R Karim A Douglas J F Han C C Weiss R A | 1998 | Physical Review Letters1998，81，： | 1 |
| 11 | Resultsfrom the 1995 national college health risk behavior survey显示文摘 | Douglas K A Collins J L Warren C | 1997 | J Am College Health1997，46，2： | 1 |
| 12 | Fecal calprotectin levels predict colorectal inflammation among patients with chronic diarrhea referred for colonoscopy显示文摘 | Paul J Limburg David A Ahlquist William J Sandborn Douglas W Mahoney Mary E Devens Jonathan J Harrington Alan R Zinsmeister | 2000 | The American Journal of Gastroenterology2000，，10： | 1 |
| 13 | Blocked isocyanates Ⅲ Part B: Uses and applications of blocked isocyanates 显示文摘 | Douglas A W Zeno W W J | 2001 | Progress in Organic Coatings2001，41，： | 1 |
| 14 | New venture survival: Ignorance,external shocks, and risk reduction strategies显示文摘 | Shepherd D A Douglas E J Shanley M | 2000 | Journal of Business Venturing2000，，： | 1 |
| 15 | Exaggerated heart rate oscillations during two meditation techniques 显示文摘 | Peng C-K and Mietus J E and Liu Y and Khalsa G and Douglas P S and Benson H and Goldberger A L | 1999 | Int J Cardiol:1999，70，： | 1 |
| 16 | Anti-microbial action of melanocortin peptides and identification of a novel X-Pro-D/L-Val sequence in Gram-positive and Gram-negative bacteria显示文摘 | CHARNLEY M MOIR A J DOUGLAS C W | 2008 | Peptides2008，29，6： | 1 |
| 17 | The peroxisome proliferator-activated receptor-γ2 Pro12Ala variant:association with type 2 diabetes and trait differences 显示文摘 | Douglas J A Erdos M R Waranabe R M | 2001 | Diabetes2001，50，： | 1 |
| 18 | Clinical value of polysomnography显示文摘 | Douglas N J Thomas S Jan M A | 1992 | Lancet1992，339，8789： | 1 |
| 19 | Enhancing food safety culture to reduce rates of foodborne illness显示文摘 | Powell Douglas A Jacob Casey J Chapman Benjamin J | | 0，，06： | 1 |
| 20 | Nutrient regulation in the pea aphid Acyrthosiphon pisum : application of a novel geometric framework to sugar and amino acid composition显示文摘 | Abisgold J D Simpson S J Douglas A E | 1994 | Physiological Entomology1994，19，： | 1 |
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