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424篇 您的检索式:作者名="DOUGLAS N"
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1Management of pancreaticobiliary disease using a new intra-ductal endoscope:The Texas experience显示文摘AIM:To evaluate a new single-operator mini-endoscope, Spyglass,for its performance,feasibility and safety in the management of pancreaticobiliary disease. METHODS:In a multicenter retrospective analysis of patients undergoing intraductal endoscopy,we evaluated 128 patients(71 men,mean age 57.6 years).Indications were therapeutic(TX)in 72(56%) and diagnostic(DX)in 56(44%). RESULTS:Peroral endoscopy was performed in 121 and percutaneous in seven.TX indications included CBD stones in 41,PD stones in six,and biliary strictures in 25.DX indications included abnormal LFT’s in 15, abnormal imaging in 38 and cholangiocarcinoma staging in three.Visualization of the stone(s)was considered good in 31,fair in six,and poor in four. Advancement of the electrohydraulic lithotripsy probe was not possible in three patients and proper targeting of the lesion was partial in four patients.A holmium laser was used successfully in three patients.Ductal clearance was achieved in 37 patients after one procedure and in four patients after two procedures.Diagnosis of biliary strictures was modified in 20/29 and confirmed to be malignant in 10/23.Of the modified patients,no diagnosis was available in 17.Spyglass demonstrated malignancy in 8/17 and non-malignancy in nine.Suspected pathology by imaging studies and abnormal LFT’s was modified in 43/63(66%).Staging of cholangiocarcinoma demonstrated multicentric cholangiocarcinoma in 2/3.There was no morbidity associated with the use of Spyglass. CONCLUSION:Spyglass Spyscopeis a first generation, single operator miniature endoscope that can evaluate and treat various biliary and pancreatic tract diseases.Douglas S Fishman Paul R Tarnasky Sandeep N Patel Isaac Raijman 2009World Journal of Gastroenterology2009,15,11:22
2系统综述与网状Meta分析的PRISMA扩展声明显示文摘PRISMA声明旨在提高系统综述和META分析报告的完整性,该声明已经广泛用于指导系统综述和META分析的报告和发表。原始的PRISMA声明是针对两种干预措施比较的传统的系统综述与META分析而制定的,然而,随着多种干预措施比较的系统综述的发展,实施和报告这一类系统综述面临较大挑战。此时,针对网状META分析的PRISMA扩展声明应运而生,旨在提高网状META分析系统综述的报告质量。PRISMA扩展声明是由专家们通过DELPHI调查、面对面讨论和共识大会而最终确立的。PRISMA扩展声明是在原始PRISMA声明的报告清单的基础上经过修改,最终确定了32个条目,每个条目均与网状META分析报告的内容直接相关。本文对网状META分析的PRISMA扩展声明进行了阐述,对报告清单各条目进行了举例说明,并详细说明了在原始PRISMA声明的基础上新增和修改各条目的理由。此外,PRISMA扩展声明强调了在网状META分析的实际操作中需要重点关注的信息。本文的目标读者包括网状META分析的作者与读者,以及期刊杂志的编辑与同行评审。李志霞 杨俊 叶欣 周凌波 杨智荣 孙凤 詹思延 Brian Hutton Georgia Salanti Deborah M.Caldwell Anna Chaimani Christopher H.Schmid Chris Cameron John P.A.Ioannidis Sharon Straus Kristian Thorlund Jeroen P.Jansen Cynthia Mulrow Ferrán Catalá-López Peter C.Gozsche Kay Dickersin Isabelle Boutron Douglas G.Altman David Moher 2016中国循证心血管医学杂志2016,8,6:11
3Competition between human cells by entosis显示文摘人的癌由被知道为营养素和生长因素间接地竞争的肿瘤房间的复杂混合物组成。肿瘤房间是否能也直接竞争,例如由对手的消除,不被知道。这里,我们证明人的房间能直接由称为 entosis 的吞没的机制竞争。由 entosis,当时,房间被吞没,或吃活,并且随后经历房间死亡。我们发现吞没的身份(“ winner”) 并且吞没(“ loser”) 房间被 RhoA 和肌动球朊控制的机械 deformability 支配,有高 deformability 的肿瘤房间在此优先地吞没并且 outcompete 有在异构的人口的低 deformability 的附近的房间。我们进一步发现那激活的 Kras 并且 Rac 发信号由 downregulating 给予获胜者地位到房间可收缩的肌浆球蛋白,允许最后经历房间死亡的附近的房间的成为主观。最后,我们计算 cell-in-cell 形成的精力风景,表明那一机械在获胜者和输家房间之间微分被要求让 entosis 继续。这些数据在发生在人的肿瘤的哺乳动物的房间定义竞争的机制。Qiang Sun Tianzhi Luo Yixin Ren Oliver Florey Senji Shirasawa Takehiko Sasazuki Douglas N Robinson Michael Overholtzer 2014Cell Research2014,24,11:8
4当在小肠的囊内视镜检查法计算路易斯分数时,蓝模式不在白光上提供任何利益显示文摘 AIM: To check the usefulness of blue mode (BM) review in lewis score (LS) calculation, by comparing it with respective LS results obtained by white light (WL) small-bowel capsule endoscopy (SBCE) review and mucosal inflammation as reflected by faecal calprotectin (FC) levels, considered as ’gold standard’ for this study. METHODS: Computational analysis of our SBCE database to identify patients who underwent SBCE with PillCam? and had FC measured within a 30-day period from their test. Only patients with prior colonoscopy were included, to exclude any colon pathology-associated FC rise. Each small bowel tertile was reviewed (viewing speed 8 fps) with WL and BM, in a back-to-back mode, by a single experienced reviewer. LS were calculated after each WL and BM reviews. Pearson rank correlation (rho, r) statistic was applied.RESULTS: Twenty-seven (n = 27, 20F/7M) patients were included. Thirteen (n = 13) had SBCE with PillCam?SB1, and the remainder (n = 14) with PillCam? SB2. The median level of FC in this cohort was 125 μg/g. LS (calculated in WL SBCE review) correlation with FC levels was r = 0.490 (P = 0.01), while for BM review and LS correlation with FC was r = 0.472 (P = 0.013).Anastasios Koulaouzidis Sarah Douglas John N Plevris 2012World Journal of Gastrointestinal Endoscopy2012,4,2:3
5Reuse of liver grafts following the brain death of the initial recipient显示文摘AIM: To determine if there is a reasonable prospect of success of a re-use liver transplantation.METHODS: We systematically searched for reports of liver graft re-use using electronic searches of PubMed and Web of Knowledge. We performed hand searches of references lists of articles reporting re-use of grafts.RESULTS: A systematic review of the literature reveals 28 liver transplantations using previously transplanted grafts. First and second recipients ranged in age from 4 to 72 years and 29 to 62 years respectively. Liver disease in the first recipient was varied including 5(18%) patients with fulminant liver failure who died subsequently of cerebral edema. The second transplanta-tion was performed after a median interval of 5 d(one day-13 years). Viral hepatitis was present in 3(11%) of the initial recipients and in 8(29%) of final recipients. Hepatocellular carcinoma was present in 6(21%) of the final recipients. Early survival after the final transplantation was 93%, whereas long-term survival was 78% with a mean follow-up of 23.3(3-120) mo.CONCLUSION: Outcomes of transplantation using previously transplanted grafts in this select population are similar to those seen with conventional grafts.Hideaki Tanaka Vivian C McAlister Mark A Levstik Cameron N Ghent Paul J Marotta Douglas Quan William J Wall 2014World Journal of Hepatology2014,6,6:3
6The evolution of manufacturing cells: An action research study显示文摘Satya Chakravorty S Douglas N H 2008European J of Operational Research2008,188,1:1
7Methotrexate therapy,rheumatoid arthritis,and life-threatening liver complications: should we be monitoring more closely?显示文摘Tugnet N Cooper SC Douglas KM 2012Scand J Rheumatol2012,41,2:1
8Automated phase correction of FT NMR spectra by baseline Optimization显示文摘Brown Douglas E Campbell Thomas W Moore Richard N 1989J Magn Reson1989,85,:1
9Fertility sparing therapy for ovarian cancer has inherent risks and benefits显示文摘Douglas N C Fan L Pothuri B 2005Arch Gynecol Obstet2005,272,4:1
10On the generation of trajectories for multiple UAVs in environments with obstacles显示文摘Armando A N Douglas G M Mado F M 2010J of Intelligent and Robotic Systems Archive2010,57,4:1
11The influence of the ionic concentration, concentration of the polymer, degree of neutralization and chain extension on biodegradable aqueous polyurethane dispersions prepared by the acetone process显示文摘Ajaya K N Douglas A W 2006Polymer2006,,47:1
12Student Conceptions of Learning and Their Use of Self-regulated Learning Strategies:A Cross-cultural Comparison显示文摘 J Hattie G Douglas 1996Journal of Educational Psychology1996,,1:1
13The association between anti-Mtlllerian hormone and IVF pregnancy outcomes is influenced by age 显示文摘Wang J G Douglas N C Nakhuda G S 2010Reprod Biomed Online2010,21,6:1
14Cellular metal lattices with hollow trusses显示文摘Queheillalt Douglas T Wadley Haydn N G 2005Acta Materialia2005,53,2:1
15Applying the lifecycle model to melanesia显示文摘Douglas N 1997Annals of Tourism Research1997,24,1:1
16The integration of design and control:IMC control and robusteness显示文摘CHAWANKUL N BUDMAN H DOUGLAS P L 2005Computers and Chemical Engineering2005,29,2:1
17Clinical value of polysomnography显示文摘Douglas N J Thomas S Jan M A 1992Lancet1992,339,8789:1
18Rehabilitation after total shoulder arthroplasty显示文摘Douglas N Robert H Keith A 2001J Arthroplasty2001,16,4:1
19显示文摘Chawankul N Budman H Douglas P L 2005Computers and Chemical Engineering2005,29,2:1
20Increased expression of urotensin Ⅱ and its cognate receptor GPR14 in atherosclerotic lesions of the human aorta显示文摘Bousette N Patel L Douglas SA 2004Atherosclerosis2004,176,:1
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