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| 1 | NEW TOXOPLASMA GONDII GENOTYPES ISOLATED FROM FREE-RANGE CHICKENS FROM THE FERNANDO DE NORONHA, BRAZIL: UNEXPECTED FINDINGS显示文摘 | Dubey J P Rajendran C Costa D G C Ferreira L R Kwok O C H Qu D Su C Marvulo M F V Alves L C Mota R A Silva J C R | 2010 | The Journal of Parasitology2010，，4： | 2 |
| 2 | Combination immunotherapy with Survivin and luteinizing hormone-releasing hormone fusion protein in murine breast cancer model显示文摘AIM To investigate the therapeutic potential of two recombinant proteins, Survivin and luteinizing hormone-releasing hormone (LHRH) fusion protein [LHRH(6 leu)-LTB] for immunotherapy of breast cancer.METHODS Murine 4 T-1 breast cancer model was used to evaluate the efficacy of recombinant proteins in vivo. Twenty four Balb/c mice were divided into 4 groups of 6 mice each. Recombinant Survivin and LHRH fusion protein, alone or in combination, were administered along with immunomodulator Mycobacterium indicus pranii (MIP) in Balb/c mice. Unimmunized or control group mice were administered with phosphate buffer saline. Each group was then challenged with syngeneic 4 T-1 cells to induce the growth of breast tumor. Tumor growth was monitored to evaluate the efficacy of immune-response in preventing the growth of cancer cells.RESULTS Preventive immunization with 20 μg recombinant Survivin and MIP was effective in suppressing growth of 4 T-1 mouse model of breast cancer (P = 0.04) but 50 μg dose was ineffective in suppressing tumor growth. However, combination of Survivin and LHRH fusion protein was more effective in suppressing tumor growth (P = 0.02) as well as metastasis in vivo in comparison to LHRH fusion protein as vaccine antigen alone.CONCLUSION Recombinant Survivin and MIP suppress tumor growth significantly. Combining LHRH fusion protein with Survivin and MIP enhances tumor suppressive effects marginally which provides evidence for recombinant Survivin and LHRH fusion protein as candidates for translating the combination cancer immunotherapy approaches. | Himani Garg Rohit Singh Hada Jagdish C Gupta G P Talwar Shweta Dubey | 2018 | World Journal of Clinical Oncology2018，9，8： | 2 |
| 3 | Role of nitric oxide in the biology, physiology and pathophysiology of reproduction 显示文摘 | ROSSELLI M KELLER P J DUBEY R K | 1998 | Hum Reprod Update1998，4，： | 1 |
| 4 | Toxoplasma gondii infection in humans and ani- mals in the United States 显示文摘 | Dubey J P Jones J L | 2008 | Int J Parasitol2008，38，11： | 1 |
| 5 | Review of Neospora caninum and neosporosis in animals 显示文摘 | Dubey J P | 2003 | Korean J Parasitol2003，41，1： | 1 |
| 6 | How Multimedia Workloads Will Change Processor Design 显示文摘 | K Diefendorff P K Dubey | 1997 | IEEE Computer1997，30，9： | 1 |
| 7 | Serologic responses of cattle and other animals infected with Neospora caninum显示文摘 | Dubey J P | 1996 | American Journal of Veterinary Research1996，57，3： | 1 |
| 8 | Structure of Toxoplasma gondii tachyzoites,bradyzoites and spo- rozoites,and biology and development of tissue cysts 显示文摘 | DUBEY J P LINDSAY S SPEER C A | 1998 | Clin Microbiol Rev1998，11，2： | 1 |
| 9 | Effect of aluminum on metabolism of starch and sugars in growing rice seedlings 显示文摘 | Mishra P Dubey R S | 2008 | Aeta Physiolo- giae Plantarum2008，30，3： | 1 |
| 10 | Genotyping of Toxoplasma gondii by multilocus PCR-RFLP markers:A high resolution and simple method for identification of parasites显示文摘 | Su C Zhang X Dubey J P | 2006 | Int Jarasitol2006，36，7： | 1 |
| 11 | Newly recognized fatal protozoan disease of dogs显示文摘 | DUBEY J P CARPENTER J L SPEER C A | 1988 | J Am Vet Med Assoc1988，192，9： | 1 |
| 12 | National Seroprevalence of Toxoplasma gondii in pigs显示文摘 | Dubey J P Leighty J C Beal V C | 1991 | J Parasitol1991，77，4： | 1 |
| 13 | Neospora-like encephalomyelitis in a calf: pathology, ultrastrueture, and immuno-reactivity显示文摘 | BARR B C CONRAD P A DUBEY J P | 1991 | J Vet Dia gn Invest1991，3，1： | 1 |
| 14 | Serologic diagnosis of toxoplasmosis in experimentally infected pregnant goats and transplacentally infected kid显示文摘 | DUBEY J P | 1985 | American J of Vet Res1985，46，5： | 1 |
| 15 | Toxoplasma gondii oocyst survival under defined temperatures显示文摘 | Dubey J P | 1998 | J Parasitol1998，84，4： | 1 |
| 16 | Xenooestrogens and phytoestrogend induce the synthesis of leukaemia inhibitory factor by human and bovine oviduct cells显示文摘 | Reinhart K C Dubey R K Keller P J | 1999 | MolHumReprod1999，10，5： | 1 |
| 17 | Lead toxicity in plants 显示文摘 | SHARMA P DUBEY R S | 2005 | Brazilian Journal of Plant Physiology2005，17，1： | 1 |
| 18 | Redescription of Neospora caninum and its differentiation from related coccidia 显示文摘 | DUBEY J P BARR B C BARTA J R | 2002 | Int J Parasitol2002，32，8： | 1 |
| 19 | Sources and rescrvoirs of Toxoplasma gondii infection on 47 Swine farms in Illinois显示文摘 | Dubey J P Weigel R M Siegel A M | 1995 | J Par- asitol1995，81，5： | 1 |
| 20 | Mouse-virulent Toxoplasma gondii isolated from feral cats on Mona island, Puerto Rieo显示文摘 | Dubey J P Lopez-Torres H Y Sundar N | 2007 | J Parasitol2007，93，6： | 1 |
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