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554篇 您的检索式:作者名="Del C J"
    题名 作者 年代 出处 被引量
1应用组织型纤溶酶原激活物行静脉溶栓治疗急性缺血性卒中的时间窗延长——美国心脏协会/美国卒中协会的科学建议显示文摘美国心脏协会卒中委员会发布了关于急性缺血性卒中的现行治疗指南,其中包括应用重组组织型纤溶酶原激活物(rt—PA)行静脉溶栓的建议。尽管该药对改善神经功能预后有一定的疗效,但由于患者通常在发病3h后方能到达医院,往往已经超过了用药的时间窗。因此,大部分缺血性卒中患者未能接受rt—PA治疗。目前研究认为,增加rt—PA治疗例数的最可能方法就是延长治疗时间窗。del Zoppo G J Saver J L Jauch E C Adams H P Jr. 2009中国脑血管病杂志2009,6,8:8
2A human ESC model for MLL-AF4 leukemic fusion gene reveals an impaired early hematopoietic-endothelial specification显示文摘MLL-AF4 熔化基因是在在婴儿的高风险的尖锐成淋巴细胞的白血病的一个特点 genomic 错误。尽管 MLL-AF4 在人的开发期间出生前地产生,这很好被建立,它在在 utero 的造血的开发的效果仍然保持未经勘探。我们创造了一个人特定的细胞的系统在 MLL-AF4-expressing 人的胚胎的干细胞(hESCs ) 学习早 hemato-endothelial 开发。介绍的功能的研究,同种细胞的分析和基因表示表明在 hESCs 的 MLL-AF4 的那表情有 phenotypic,功能并且基因表示影响。MLL-AF4 在 hESCs 充当全球 transcriptional 使活跃之物和 homeobox 基因表示的一个积极管理者。机能上地, MLL-AF4 从 hESCs 提高 hemogenic 先锋的说明,但是强烈损害进一步造血的承诺赞成 endothelial 房间命运。MLL-AF4 hESCs transcriptionally 被告知向对 endothelial 成熟敏感的 hemogenic 先锋区分,由联系到 vascular-endothelial 功能和早造血作用的主人基因的显著 upregulation 思考了。而且,我们报导那 MLL-AF4 表情不是足够的转变导出 hESC 的造血的房间。这个工作说明 hESCs 怎么可以提供唯一的卓见进人的开发并且推进我们理解白血病的熔化基因,知道出生前地产生,调整人的胚胎的造血的说明。Clara Bueno Rosa Montes Gustavo J Melen Verdnica Ramos-Mejia Pedro J Real Ver6nica Ayllo'n Laura Sanchez Gertmdis Ligero Inmaculada Gutierrez-Aranda Agustin F Femfindez Mario F Fraga Inmaculada Moreno-Gimeno Deborah Btlrks Maria del Carmen Plaza-Calonge Juan C Rodriguez-Manzaneque Pablo Menendez 2012Cell Research2012,22,6:2
3显示文摘del Valle J A Picasso A C Alvarez I 1999Scripta Materialia1999,41,3:1
4The food contami- nant deoxynivalenol, decreases intestinal barrier permeability and reduces claudin expression 显示文摘Pinton P Nougayrede J P Del rio J C 2009Toxicol Appl Pharmacol2009,237,:1
5The role of ecological theory and practice in poverty alleviation and environmental conservation 显示文摘DeClerck F Ingram J C Del Rio C M R 2006The Ecological Society of America2006,4,10:1
6Mechanical properties of polyester mooring cables 显示文摘FERNANDES A C DEL VECCI-IIO C J M CASTRO G A V 1999International Journal of Offshoreand Polar Engineering1999,9,3:1
7Control of the chemical structure of perhydrous coals : FTIR and Py-GC/MS investigation显示文摘IGLESIAS M J del RIIO J C LAGGOUN-D FARGE F CUESTA M J SU REZ-RUIZ I 2002J Anal Appl Pyrolysis2002,62,1:1
8Anemia and chronic kidney disease are potential risk factors for mortality in stroke patients:a historic cohort study显示文摘Del Fabbro P Luthi J C Carrera E 2010BMC Nephrol2010,11,6:1
9Leveraging ecological knowledge to end global poverty 显示文摘Del Rio C M R Ingram J C DeClerck F 2005Frontiers in Ecology and the Environment2005,3,9:1
10Low educational level: a risk factor for sexually transmitted infections among commercial sex workers in Quito, Ecuador 显示文摘Solomon MM Smith M J del Rio C 2008Int J STD AIDS2008,19,4:1
11A study of sulfur functionalities in fossil fuels using destructive-( ASTM and Py-GC-MS) and non-destructive-( SEM-EDX, XANES and XPS) techniques 显示文摘OLIVELLA M A PALACIOS J M VAIRAVAMURTHY A DEL RIO J C De LAS HELLAS F X C 2002Fuel2002,81,4:1
12Bleaching of kaolins and clays by chlorination of iron and titanium显示文摘González J A Ruiz M del C 2006Applied Clay Science2006,33,34:1
13Analysis and optimization of the heat-insula-ting light concrete hollow brick walls design by the finite element method 显示文摘Del Coz Diaz J J Garcfa Nieto P J Betegrn Biempica C 2007Applied Thermal Engineering2007,27,89:1
14Arabidopsis E2Fc functions in cell division and is degraded by the ubiquitin-SCF(At SKP2) pathway in response to light显示文摘DEL POZO J C BONIOTTI M B GUTIERREZ C 2002Plant Cell2002,14,:1
15Cell cycle activation in striatal neurons from Huntington'sdisease patients and rats treated with 3-nitropropionic acid 显示文摘Pelegrl C Duran-Vilaregut J del Valle J 2008Int J Dev Neurosci2008,26,7:1
16Development and use of a multiplex real-time quantitative polymerase chain reaction assay for detection and differentiation of porcine circovirus-2 genotypes 2a and 2b in an epidemiological survey显示文摘Gagnon C A Del Castillo J R Music N 2008J Vet Diagn Invest2008,20,5:1
17Conductivity Studies of Solid Polymer Electrolytes Based on Polyethers and Polyphosphazene Blends显示文摘 Martin A P J Acosta J L 1998Journal of Applied Polymer Science1998,70,11:1
18Treatment of acute ischemic stroke: Challenging the concept of a rigid and universal time window显示文摘Baron J C Von Kummer R Del Zoppo G J 1995Stroke1995,26,12:1
19Influence of age and geo-graphical origin in the prevalence of high risk humanpapillomavirusin migrant female sex workers in Spain 显示文摘Del Arlno J Gonzalez C Losana J 2005Sex Transm Infect2005,81,1:1
20Corrosion behaviour of AZ31 magnesium alloy with different grain sizes in simulated biological fluids 显示文摘ALVAREZ-LOPEZ M PEREDA M D DEL VALLE J A FERNANDEZ-LORENZO M GARCIA-ALONSO M C RUANO OA ESCUDERO M L 2010Acta Biomaterialia2010,6,:1
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