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| 1 | The wonders of BMP9:From mesenchymal stem cell differentiation,angiogenesis,neurogenesis,tumorigenesis,and metabolism to regenerative medicine显示文摘Although bone morphogenetic proteins(BMPs)initially showed effective induction of ectopic bone growth in muscle,it has since been determined that these proteins,as members of the TGF-b superfamily,play a diverse and critical array of biological roles.These roles include regulating skeletal and bone formation,angiogenesis,and development and homeostasis of multiple organ systems.Disruptions of the members of the TGF-b/BMP superfamily result in severe skeletal and extra-skeletal irregularities,suggesting high therapeutic potential from understanding this family of BMP proteins.Although it was once one of the least characterized BMPs,BMP9 has revealed itself to have the highest osteogenic potential across numerous experiments both in vitro and in vivo,with recent studies suggesting that the exceptional potency of BMP9 may result from unique signaling pathways that differentiate it from other BMPs.The effectiveness of BMP9 in inducing bone formation was recently revealed in promising experiments that demonstrated efficacy in the repair of critical sized cranial defects as well as compatibility with bone-inducing bio-implants,revealing the great translational promise of BMP9.Furthermore,emerging evidence indicates that,besides its osteogenic activity,BMP9 exerts a broad range of biological functions,including stem cell differentiation,angiogenesis,neurogenesis,tumorigenesis,and metabolism.This review aims to summarize our current understanding of BMP9 across biology and the body. | Sami Mostafa Mikhail Pakvasa Elam Coalson Allen Zhu Alex Alverdy Hector Castillo Jiaming Fan Alex Li Yixiao Feng Di Wu Elliott Bishop Scott Du Mia Spezia Alissa Li Ofir Hagag Alison Deng Winny Liu Mingyang Li Sherwin S·Ho Aravind Athiviraham Michael J·Lee Jennifer Moriatis Wolf Guillermo A·Ameer Hue H·Luu Rex C·Haydon Jason Strelzow Kelly Hynes Tong-Chuan He Russell R·Reid | 2019 | Genes & Diseases2019，6，3： | 15 |
| 2 | 柑桔黄龙病的鉴定和柯赫氏定理(英文)显示文摘黄龙(梢)病被认为是世界柑橘生产上的毁灭性病害已超过一个世纪,但该病害的病原学至今还没有清晰地建立起来。根据16S rRNA基因序列分析,一组被称为'Candidatus Liberibacter species'的难培养细菌被认为与黄龙病相关。然而,要确定'Ca.Liberibacter spp.'是黄龙病病原的柯赫氏定理并没有真正完成。令我们担忧的是,近年来有些文献频频指出'Ca.Liberibacter spp.'是黄龙病的病原,其实该细菌与柑橘寄主的直接病理反应还没有完全确定。我们建议,在黄龙病病原学清楚之前,文献报道在这方面需要有准确的阐述。 | Chen J Deng X Civerolo E L Lee R F Jones J B Zhou C Hartung J S Manjunath K L Brlansky R H | 2011 | 植物病理学报2011，41，2： | 10 |
| 3 | Generalization of a retarded Gronwall-like inequality and its applications 显示文摘 | Agarwal R P Deng S Zhang W | 2005 | Appl Math Comput2005，165，： | 1 |
| 4 | 2D structure with rectangular grids woven by coordination chains and pseudo-metal wires 显示文摘 | ZHANG H X KANG B S DENG L R | 2001 | Inorg Chem Commun2001，4，： | 1 |
| 5 | Insens:Intrusion tolerant routing for wireless sensor networks显示文摘 | DENG Jing HAN R MISHRA S | 2006 | Computer Communications2006，29，2： | 1 |
| 6 | Contrasting effects of elevated CO2 on Cu and Cd uptake by different rice varieties grown on contaminated soils with two levels of metals: Implication for phytoextraction and food safety显示文摘 | Li Z Y Tang S R Deng X F | 2010 | Journal of hazardous materials2010，177，13： | 1 |
| 7 | Bacterial community structure and diversity in a century - old manure - treated agroecosystem 显示文摘 | Sun H Y Deng S P Raun W R | 2004 | Ap- plied and Environmental Microbiology2004，70，10： | 1 |
| 8 | Progesterone receptor ligand binding pocket flexibility: Crystal structures of the norethindrone and mometasone furoate complexes显示文摘 | Madauss K P Deng S J Austin R J | 2004 | J Med Chem2004，47，13： | 1 |
| 9 | Inuence of silver ions on bioleaching of cobalt from spent lithium batteries 显示文摘 | Zeng G S Luo S L Deng X R | 2013 | Minerals Engineering2013，49，1： | 1 |
| 10 | Application of an antibacterial dressing spray in the prevention of post-operative infection in oral cancer patients:a phase 1 clinical trial显示文摘 | ZENG Y Z DENG R Z YEUNG H S | 2008 | Afr J Biotechnol2008，7，21： | 1 |
| 11 | Characteristics of a bioflocculant produced by Bacillus mucilaginosus and its use in starch wastewater treatment显示文摘 | Deng S B Bai R B Hu X M | 2003 | Appl Microbiol Biotechnol2003，60，： | 1 |
| 12 | A copper -catalyzed bioleaching process for enhancement of cobalt dissolution from spent lithium - ion batteries 显示文摘 | Zeng G S Deng X R Luo S L | 2012 | Journal of Hazardous Materials2012，，15： | 1 |
| 13 | Chaotic motion of a horizontal impact pair显示文摘 | Han R P S Luo A C J Deng W | 1995 | Journal of Sound and Vibration1995，181，2： | 1 |
| 14 | Bacterial community structure and diversity in a century-old manure-treated agroecosystem显示文摘 | Sun H Y Deng S P Raun W R | 2004 | Applied and Environmental Microbiology2004，70，： | 1 |
| 15 | Characteristics of a widespread community cluster of H275Y oseltamivir-resistant A (H1N1) pdm09 influenza in Australia显示文摘 | Hurt A C Hardie K Wilson N J Deng Y M Oshourn M Leang S K Lee R T Iannello P Gehrig N Shaw R Wark P Caldwell N Givney R C Xue L Maurer- Stroh S Dwyer D E Wang B Smith D W Levy A Booy R Dixit R Merritt T Kelso A Dalton C Durrheim D Barr I G | 2012 | J Infect Dis2012，206，2： | 1 |
| 16 | Asymptotic property of stochastic population dynamics 显示文摘 | Pang S Deng F Mao X R | 2008 | Dynam Contin Discrete Impuls Syst: Math Anal2008，15，： | 1 |
| 17 | Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and CT18显示文摘 | Deng W Liou S R Plunkett Ⅲ G | 2003 | Bacterial2003，185，7： | 1 |
| 18 | Simultaneous determination of bioactive flavone derivatives in Chinese herb extraction by capillary electrophoresis used different electrolyte systems--Borate and ionic liquids显示文摘 | Qi S D Li Y Q Deng Y R | 2006 | J Chromatography A2006，，1109： | 1 |
| 19 | Multivariate factor analysis of sulfur oxidation and rhodanese activity in soil显示文摘 | Dick R P Deng S | 1991 | Biogeochemistry1991，12，： | 1 |
| 20 | Benzene-based poly- organodisulfide cathode materials for secondary lithium batteries显示文摘 | Deng S R Kong L B Hu G Q | 2006 | Electrochim Acta2006，51，13： | 1 |
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