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| 1 | High-dose methylprednisolone can induce remissions in patients with fludarabine- refractory chronic lymphocytic leukaemia显示文摘 | Xu, W Miao, KR Hong, M Zhu, DX Fang, C Dong, HJ Wang, DM Cao, X Li, JY | 2010 | 南京医科大学学报(自然科学版)2010,30,11: | 5 |
| 2 | 查看详情显示文摘 | W C Huang H Y Tam P K A Wai X Y Dong H Ming J P Xie | | 中国物理快报(英文版)0,,: | 4 |
| 3 | Next generation patient-derived prostate cancer xenograft models显示文摘对为前列腺癌症的更有效的治疗学的途径有批评需要。然而,在这个区域的研究被缺乏严重妨碍了临床上相关,在疾病的 vivo 模型试验性。这评论特别地基于 patients’ 的 subrenal 囊 grafting 集中于前列腺癌症异种皮移植模型的发展;进 nonobese 糖尿病 / 严重的肿瘤组织联合了 immunodeficient (NOD/SCID ) 老鼠。这种技术允许可移植的、导出病人的癌症织物异种皮移植线的成功的开发从不仅好攻击变形,而且从局部性的前列腺癌症纸巾。异种皮移植被发现了保留原来的恶意的关键生物性质,包括组织病理学说、分子的特征,肿瘤异质,对雄激素脱离的反应和变形能力。因此,他们是高度临床上相关并且在细胞、分子的层次,为个性化的癌症治疗屏蔽的药和现出症状之前的潜的药为前列腺癌症前进的研究提供珍贵工具测试的功效;特别当模型的一块面板习惯于盖子时许多疾病。这些异种皮移植模型能因此被看作前列腺癌症的下一代的模型。 | Dong Lin Hui Xue Yuwei Wang Rebecca Wu Akira Watahiki Xin Dong Hongwei Cheng Alexander W Wyatt Colin C Collins Peter W Gout Yuzhuo Wang | 2014 | Asian Journal of Andrology2014,16,3: | 4 |
| 4 | 可卡因暴露通过miR-30C-5P/苹果酸酶1/活性氧通路升高血压和加强主动脉僵硬度显示文摘滥用可卡因可增加心血管病死亡和发病风险,然而,其中潜在的分子机制仍然未知。通过可卡因滥用小鼠模型,Zhu等发现重复注射可卡因可导致小鼠血压升高和主动脉僵硬度增加(主动脉中活性氧水平同时升高),这种现象类似于人类高血压中观察到的现象。 | 刘莉 叶鹏 Zhu W Wang H Wei J Sartor GC Bao MM Pierce CT Wahlestedt CR Dykxhoorn DM Dong C | 2018 | 中华高血压杂志2018,26,4: | 4 |
| 5 | Machine learning models compared to existing criteria for noninvasive prediction of endoscopic retrograde cholangiopancreatography-confirmed choledocholithiasis显示文摘Background and aims:Noninvasive predictors of choledocholithiasis have generally exhibited marginal performance characteristics.We aimed to identify noninvasive independent predictors of endoscopic retrograde cholangiopancreatography(ERCP)-confirmed choledocholithiasis and accordingly developed predictive machine learning models(MLMs).Methods:Clinical data of consecutive patients undergoing first-ever ERCP for suspected chol-edocholithiasis from 2015 to 2019 were abstracted from a prospectively-maintained database.Multiple logistic regression was used to identify predictors of ERCP-confirmed choledocholithiasis.MLMs were then trained to predict ERCP-confirmed choledocholithiasis using pre-ERCP ultrasound(US)imaging only as well as using all available noninvasive imaging(US,computed tomography,and/or magnetic reso-nance cholangiopancreatography).The diagnostic performance of American Society for Gastrointestinal Endoscopy(ASGE)“high-likelihood”criteria was compared to MLMs.Results:We identified 270 patients(mean age 46 years,62.2%female,73.7%Hispanic/Latino,59%with noninvasive imaging positive for choledocholithiasis)with native papilla who underwent ERCP for suspected choledocholithiasis,of whom 230(85.2%)were found to have ERCP-confirmed chol-edocholithiasis.Logistic regression identified choledocholithiasis on noninvasive imaging(odds ratio(OR)¼3.045,P¼0.004)and common bile duct(CBD)diameter on noninvasive imaging(OR¼1.157,P¼0.011)as predictors of ERCP-confirmed choledocholithiasis.Among the various MLMs trained,the random forest-based MLM performed best;sensitivity was 61.4%and 77.3%and specificity was 100%and 75.0%,using US-only and using all available imaging,respectively.ASGE high-likelihood criteria demonstrated sensitivity of 90.9%and specificity of 25.0%;using cut-points achieving this specificity,MLMs achieved sensitivity up to 97.7%.Conclusions:MLMs using age,sex,race/ethnicity,presence of diabetes,fever,body mass index(BMI),total bilirubin,maximum CBD diameter,and choledocholithiasis on pre-ERCP noninvasive imaging predict ERCP-confirmed choledocholithiasis with good sensitivity and specificity and outperform the ASGE criteria for patients with suspected choledocholithiasis. | Camellia Dalai John M Azizian Harry Trieu Anand Rajan Formosa C Chen Tien Dong Simon W Beaven James H.Tabibian | 2021 | Liver Research2021,5,4: | 3 |
| 6 | A study of the short wave components in computational acoustics 显示文摘 | Tam C K W Webb J C Dong Z | 1993 | Journal of Computational Acoustics1993,1,: | 2 |
| 7 | Magnetic domain observations of freestanding single crystal patterned Ni2MnGa films 显示文摘 | PAN Q DONG J W PALMSTROM C J | 2002 | Journal of Applied Physics2002,91,10: | 1 |
| 8 | Improvement of fatigue properties by shot peening for Mg-10Gd-3Y alloys under different conditions显示文摘 | LIU W C DONG J AHANG P | 2011 | Materials Science and Engineering (A)2011,528,: | 1 |
| 9 | Relationships between biomass, pressure drop, and performance in a polyurethane biofilter 显示文摘 | Hee W R Kyung-Suk Cho Dong J C | 2010 | Bioresource Technology2010,101,6: | 1 |
| 10 | Synthesis of star- shaped poly (D, L-lactic acid-alt-glycolic acid)-b-poly(L- lactic acid) with the poly (D, L-lactic acid-alt-glycolic acid) macroinitiator and stannous octoate catalyst 显示文摘 | Dong C M Qiu K Y Gu Z W | 2002 | Journal of Polymer Science Part A: Polymer Chemistry2002,40,3: | 1 |
| 11 | Zinc oxide nanodisk 显示文摘 | Xu C X Sun X W Dong Z L | 2004 | Appl Phys Lett2004,85,17: | 1 |
| 12 | Diurnal fluctuations in oxygen release from roots of acoruscalamus 1inn in a modeled constructed wetland 显示文摘 | DONG C ZHU W GAO M | 2011 | Journal of Environmental Science and Health : Part A2011,46,: | 1 |
| 13 | Heterotrimeric G proteins regulate nitrogen-use efficiency in rice 显示文摘 | Sun H Y Qian Q Wu K Luo J J Wang S S Zhang C W Ma Y F Liu Q Huang X Z Yuan Q B Han R X Zhao M Dong G J Guo L B Zhu X D Gou Z H Wang W Wu Y J Lin H X Fu X D | 2014 | Nature Genetics2014,46,4: | 1 |
| 14 | An overview of a new chinese weather satellite FY-3 A 显示文摘 | Dong C Yang J Zhang W | 2009 | Bulletin of the American Meteorological Society2009,90,: | 1 |
| 15 | Vertex methods for computing functions on fuzzy variables显示文摘 | DONG W SHAN H C | 1987 | Fuzzy Sets and Systems1987,24,: | 1 |
| 16 | cDNA cloning and ex- pression of a novel estrogen receptor β-subtype in goldfish (Carassius auratus) 显示文摘 | Ma C H Dong K W Yu K L | 2000 | Biochim Biophys Acta2000,1490,: | 1 |
| 17 | Occurrence of avian leukosis virus subgroup J in commercial layer flocks in China 显示文摘 | Xu B Dong W Yu C | 2004 | Avian Pathol2004,33,1: | 1 |
| 18 | A fluxless fabrication process producing Sn - rich Bi - Sn joints with high melting temperature 显示文摘 | Chin C Lee Ricky W Chuang Dong W Kim | 2004 | Materials science and engineering A2004,374,: | 1 |
| 19 | EPR parameters and superposition model analysis for trigonal Dy^3+ O2^- center in CaF2 crystal 显示文摘 | Zheng W C Dong H N Wu S Y | 2004 | Physica B2004,334,: | 1 |
| 20 | A Lightweight and Density-awareReprogramming Protocol for Wireless Sensor Networks显示文摘 | Dong W Chen C Liu X | 2011 | IEEETransactions on Mobile Computing2011,10,10: | 1 |