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904篇 您的检索式:作者名="Drewes J"
    题名 作者 年代 出处 被引量
1Methylation of TIMP3 in esophageal squamous cell carcinoma显示文摘AIM: To measure the frequency of DNA methylation of the tissue inhibitor of metalloproteinase 3 (TIMP3) promoter and relate this to any change of gene expression in esophageal squamous cell carcinoma in patients from a region of high incidence in China.METHODS: Cancer cell lines were treated with or without the demethylating reagent 5-aza-2’-deoxycytidine. Methylation of the TIMP3 promoter was assessed in three regions by melt curve analysis and its expression was assessed by real-time RT-PCR. Tumors and proximal resection margins were obtained from 64 patients with esophageal squamous cell carcinoma from a region of high incidence in China. Methylation was assessed by melt curve analysis and expression by immunohistochemistry.RESULTS: Methylation in one of the three promoter regions assessed correlated with gene silencing in esophageal cell lines. A degree of methylation of TIMP3 was found in only four esophageal squamous cell carcinomas, and partial loss of TIMP3 protein expression in just one.CONCLUSION: Methylation and loss of expression of TIMP3 occurs infrequently in esophageal squamous cell carcinoma in a region of high incidence in China.Eric Smith Neville J De Young Zi-Qiang Tian Maria Caruso Andrew R Ruszkiewicz Jun-Feng Liu Glyn G Jamieson Paul A Drew 2008World Journal of Gastroenterology2008,14,2:2
2The interaction of reaction-bonded silicon carbide and Inconel 600 with a nickel-based brazing alloy显示文摘Mcdermid J R Pugh M D Drew R A L 1989Metallurgical Transactions A1989,20,:1
3Variation in open reading frames 3, 4 and 7 among porcine reproductive and respiratory syndrome virus isolates in the UK 显示文摘Drew T W Lowings J P Yapp F 1997Vet Microbiol1997,55,14:1
4Geology and structural evolution of the Muruntau gold deposit, Kyzylkum Desert, Uzbekistan 显示文摘 Berger B R Kurbanov N K 1996Ore Geology Reviews1996,11,:1
5Glueagon - like peptide - 1 promotes satiety and reduces food in take in patients with diabetes mellitus type 2 显示文摘Gutzwiller JP Drewe J Goke B 1999Am J Physiol Regul lntegr Comp Physiol1999,276,:1
6Phosphorylation of Ser262 strongly reduced binding of tan to microtubules: distinction between PHF-like immunoreactivity and microtubule binding显示文摘Biemat J Gustke N Drewes G 1993Neuron1993,11,1:1
7Spectrally arbitrary patterns显示文摘Drew J H Johnson C R Olesky D D 2000Linear Algebra Appl2000,308,13:1
8Longitudinal analysis of the impact of service changes on customer attitudes显示文摘Bolton R N Drew J H A 0,,:1
9Multiple paternity in a natural population of a wild tobacco fly, Bactrocera cacuminata (Diptera: Tephritidae), assessed by microsatellite DNA markers 显示文摘Song S D Drew R A Hughes J M 2007Molecular Ecology2007,16,11:1
10Facilitation of oviposition behaviour of Bactrocera tryoini flies显示文摘PROKOPY R J REMING M C DREW R A I 1999Journal of Insect Behavior1999,12,:1
11Rapid determination of particle velocity from space-time images using the Radon transform 显示文摘Drew P J Pablo B Gert C 2010Journal of Computational Neuro- science2010,29,1:1
12The role of long chain fatty acids in regulating food intake and cholecystokinin release in humans显示文摘Matzinger D Degen L Drewe J 2000Gut2000,46,:1
13Programmed cell death and aerenchyma formation in roots显示文摘Drew M C He C J Morgan P W 2000Trends in Plant Science2000,5,3:1
14The role of long chain fatty acids in regulating food intake and cholecystokinin release in humans 显示文摘MATZINGER D DEGEN L DREWE J 2000Gut2000,46,5:1
15Homologous recombination deficiency and ovarian cancer 显示文摘Ledermann J A Drew Y Kristeleit R S 2016Eur J Cancer2016,60,:1
16Spectrally arbitrary patterns显示文摘Drew J H Johnson C R Olesky D D 2000Linear Algebra Appl ( S0024-3795 )2000,308,:1
17Liposomal amphoterlcin B: clinical experience and perspectives显示文摘GIBBS W J DREW R H PERFECT J R 2005Eepert Rev Anti Infect Ther2005,3,2:1
18Completely positive matrices Associated With M-Matrices显示文摘 C R Johnson R Loewy 1994Linear Multilinear Algebr1994,37,2:1
19Stand density management: an alternative approach and its application to Douglasfir plantation 显示文摘Drew T J Flewelling J W 1979Forest Science1979,25,:1
20An investigation of the propagation of pressure perturbation in bubbly air/water flow显示文摘RUGGLES A E LAHEY R T J DREW D A 1988Heat Transfer1988,1,10:1
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