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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Dependency of Colorectal Cancer on a TGF-β-Driven Program in Stromal Cells for Metastasis Initiation显示文摘 | Alexandre Calon Elisa Espinet Sergio Palomo-Ponce Daniele V.F. Tauriello Mar Iglesias María Virtudes Céspedes Marta Sevillano Cristina Nadal Peter Jung Xiang H.-F. Zhang Daniel Byrom Antoni Riera David Rossell Ramón Mangues Joan Massagué Elena Sancho Edua | 2012 | Cancer Cell2012，，5： | 2 |
| 3 | Glutamine synthetase and glutamate dehydrogenase isoforms in maize leaves:Localization,relative proportion and their role in ammonium assimilation or nitrogen transport显示文摘 | Thomas W B Elisa C Bertrand H | 2000 | Planta2000，211，： | 1 |
| 4 | Must treatments and wild yeastgrowth before and during alcoholic fermentation 显示文摘 | Agostino C Elisa P Raffaele G | 2011 | Ann Micro-biol2011，，6： | 1 |
| 5 | Biological effects of 6 mT static magnetic fields: A comparative study in different cell types 显示文摘 | Bernadette T Alfonsina C Elisa P | 2006 | Bioelectromagnetics2006，27，7： | 1 |
| 6 | Auxin Synthesis-Encoding Transgene Enhances Grape Fecundity显示文摘 | Elisa C Lucia L Oriana S | 2007 | Plant Physiology2007，143，4： | 1 |
| 7 | Mental Workload and Visual Impairment: Differences be- tween Pupil, Blink, and Subjective Rating 显示文摘 | Miguel A R Elisa P Angela C | 2008 | The Spanish Journal of Psychology2008，11，2： | 1 |
| 8 | Environmental expo- sure to asbestos and other inorganic fibers using animal lung model显示文摘 | Elisa F Elena B Silvana C | 2009 | Total Envir2009，407，3： | 1 |
| 9 | Solid-phase mi- croextraction as a clean-up and preconcentration proce- dures for organochlorine pesticides determination in fish tissue by gas chromatography with electron capture detec- tion显示文摘 | Natalia F U Giusepp C Elisa B G | 2003 | J Chromatogr A2003，1017，： | 1 |
| 10 | Combined HSV-TK/IL-2 gene therapy in patients with recurrent glioblastoma multiforme: biological and clinical result 显示文摘 | FEDERICO C LUISA B ELISA F | 2005 | Cancer Gene Therapy2005，12，： | 1 |
| 11 | Short-Term postharvest carbondioxide treatments induce selective molecular and metabolic changes in grape berries显示文摘 | Elisa B Lamia C Pietro T | 2010 | Journal of Agricultural and Food Chemistry2010，58，13： | 1 |
| 12 | Overexpression of Osmyb4 enhances compatible solute accumulation and increases stress tolerance of Arabidopsis thaliana 显示文摘 | Monica M Elisa B Roberto C | 2005 | PhysiolPlanta2005，1259，2： | 1 |
| 13 | Solid - phase microextraction as a clean - up and preconcentration procedure for organochlorine pesticides determination in fish tissue by gas chromatography with electron capture detection 显示文摘 | Natalia F U Giuseppe C Elisa B G | 2003 | Journal of Chromatography A2003，1017，： | 1 |
| 14 | Cardiomyopathy familial dilated显示文摘 | Matthew RG Elisa C Luisa M | 2006 | Orphanet J of Rare Diseases2006，1，1： | 1 |
| 15 | Optical and structural investigation on rare-earth-doped aluminophosphate glasses显示文摘 | Elisa M Vasiliu I C Cristiana E A | 2006 | Optical Materials2006，28，： | 1 |
| 16 | Sol-gel combustion synthesis of BNBT powders显示文摘 | Elisa M Carmen G Anna L C | 2008 | Journal of Sol-Gel Science and Technology2008，46，： | 1 |
| 17 | Integrating XML and databases显示文摘 | Elisa B Barbara C | 2001 | IEEE Internet Computing2001，5，4： | 1 |
| 18 | Analysis of the effects of specific protease inhibitors on OPG/RANKL regulation in an osteoblast-like cell line显示文摘 | Davide G Marco B Elisa C etal | 2010 | The New Microbiologica2010，33，2： | 1 |
| 19 | Ultrasound in enzymatic resolution of ethyl 3-hydroxy-3-phenylpropanoate 显示文摘 | Carlos Magno R Ribeiro Elisa N Passaroto Eugenia C S Brenelli | 2001 | Tetrahedron Letters2001，42，： | 1 |
| 20 | Selective chemical oxidation or reduction of chlorophenols with potassium nitro-sodisulfonate显示文摘 | Elisa L Ismael C Edgar M | 2003 | Organic Chemistry in Mexico2003，7，： | 1 |
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