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1Single-center study comparing computed tomography colonography with conventional colonoscopy显示文摘AIM:To compare the results from computed tomography (CT) colonography with conventional colonoscopy in symptomatic patients referred for colonoscopy. METHODS: The study included 227 adult outpatients, mean age 60 years, with appropriate indications for colonoscopy. CT colonography and colonoscopy were performed on the same day in a metropolitan teaching hospital. Colonoscopists were initially blinded to the results of CT colonography but there was segmental unblinding during the procedure. The primary outcome measures were the sensitivity and specificity of CT colonography for the identification of polyps seen at colonoscopy (i.e. analysis by polyp). Secondary outcome measures included an analysis by patient, extracolonic findings at CT colonography, adverse events with both procedures and patient acceptance and preference. RESULTS: Twenty-five patients (11%) were excluded from the analysis because of incomplete colonoscopy or poor bowel preparation that affected either CT colonography, colonoscopy or both procedures. Polyps and masses (usually cancers) were detected at colonoscopy and CT colonography in 35% and 42% of patients, respectively. Of nine patients with a finaldiagnosis of cancer, eight (89%) were identified by CT colonography as masses (5) or polyps (3). For polyps analyzed according to polyp, the overall sensitivity of CT colonography was 50% (95% CI, 39%-61%) but this increased to 71% (95% CI, 52%-85%) for polyps ≥ 6 mm in size. Similarly, specificity for all polyps was 48% (95% CI, 39%-58%) increasing to 67% (95% CI, 56%-76%) for polyps ≥ 6 mm. Adverse events were uncommon but included one colonic perforation at colonoscopy. Patient acceptance was high for both procedures but preference favoured CT colonography. CONCLUSION: Although CT colonography was more sensitive in this study than in some previous studies, the procedure is not yet sensitive enough for widespread application in symptomatic patients.Ian C Roberts-Thomson Graeme R Tucker Peter J Hewett Peter Cheung Ruben A Sebben EE Win Khoo Julie D Marker Wayne K Clapton 2008World Journal of Gastroenterology2008,14,3:4
2Prognostic factors and outcomes for osteosarcoma: an international collaboration 显示文摘Pakos EE Nearchou AD Grimer R J 2009Eur J Cancer2009,45,13:1
3Renal cell carcinoma invading the urinary collecting system: implications for staging 显示文摘Uzzo RG Cherullo EE Myles J 2002J Urol2002,167,6:1
4Randomized phase Ⅱ study of cisplatin with gemcitabin or paclitaxel or vinorelbine as induction chemotherapy followed by concomitant chemoradiotherapy for stage ⅢB Non-small Cell Lung Cancer:cancer and leukemia group B study 9431显示文摘Vokes EE Herndon JE Crawford J 2002J Clin Oncol2002,20,:1
5Familial cyclic vomiting syndrome 显示文摘Haan J Kors EE Ferari MD 2002Cephalalgia2002,22,7:1
6Storage and executive processes in the frontal lobes显示文摘Smith EE Jonides J 1999Science1999,283,5408:1
7Inhibition of fertility in female mice by immunization with a B-cell epitope, the synthetic sperm peptide, PIOG显示文摘O'Rand MG Beavers J Widgren EE 1993J Reprod lmmunol1993,25,2:1
8Cross-transfusion of postshock mesenteric lymph provokes acute lung injury显示文摘Wohlauer MV Moore EE Harr J 2011J Surg Res2011,170,2:1
9Storage and executive processes in the frontal lobes显示文摘Smith EE Jonides J 1999Science1999,283,5408:1
10Assessment of lung development using hyperpolarized helium- 3 diffusion MR imaging显示文摘Altes T Mata J Lange EE 2006J Magn Reson Imaging2006,24,6:1
11Acitretin in psoriasis: an overview of adverse effects显示文摘Katz HI Waalen J Leach EE 1999J Am Acad Dermatol1999,41,32:1
12Morbidity and mor- tality rates in elderly patients undergoing percutaneous coronary transluminal angioplasty 显示文摘Lindsay J Jr Reddy ~M Pinnow EE 1994Am Heart J1994,128,:1
13Epidemiology of severe injuries among United States high school athletes 2005- 2007 显示文摘Darrow C J Collins CL Yard EE 2009Am J Sports Med2009,37,9:1
14Radiologic concepts of lymphoma of bone显示文摘Edeiken-Monroe B Edeiken J Kim EE 0,,:1
15Comparison ofwhole chloroplast genome sequences to choose noncodingregions for phylogenetic studies in angiosperms : the tor-toise and the hare III 显示文摘Shaw J Lickey E B Schilling EE 2007American Journal of Botany2007,94,3:1
16Neonatal stenotic Ebstein's anomaly: a novel technique of right ventricular exclusion显示文摘Yun T J L ee S H Ko J K 2006Thorac Cardiovasc Surg2006,131,2:1
17Storage and executive processes in the frontal lobes显示文摘Smith EE Jonides J 1999Science1999,283,5408:1
18Assessment of menorrhagia in females followed for bleeding disorders at the hemophilia center of western new york coelation between elinical presentation and laboratory parameters显示文摘Bush EE Kepner J Smiley S 2006Blood2006,108,:1
19Effect of surface modification onthe resin-transfer moulding (RTM) of glass-fibre/unsaturated-polyester composites 显示文摘LEE G W EE N J JANG J 2002Compos Sci Technol2002,62,:1
20Comparison of the femtosecond laser and mechanical keratome for laser in situ keratomileusis 显示文摘Chart A Ou J Manche EE 2008Arch Ophthalmol2008,125,11:1
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