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| 1 | Effect of mucin production on survival in colorectal cancer:A case-control study显示文摘AIM: To investigate the impact of mucin production on prognosis in colorectal cancer, in terms of overall survival (OS) and time to disease progression (TTP) in patients with mucinous compared to those with non-mucinous colorectal cancer (NMCRC), matched for age, gender, and tumor stage.METHODS: Thirty five patients with mucinous colorectal cancer (MCRC) were matched for age, gender, and tumor stage with 35 controls having NMCRC. OS and TTP were compared among 4 groups divided according to mucin content: group A (50%-75% mucin), group B (75%-100% mucin), group C or controls (< 50% mucin). Group D consisted of all patients with tumors having < 75% mucin (controls and groups A together).RESULTS: Median survival in MCRC and NMCRC groups was 46.2 and 112.9 mo, respectively (P = 0.26). OS in groups A and B was 70.1 and 32.8 mo (P = 0.46), and in groups B and D was 32.8 and 70.1 mo, respectively (P = 0.143). TTP in MCRC and NMCRC was 50.17 and 44.77 mo, respectively (P = 0.795). TTP in groups A, B, and D was 70.1, 24.8, and 65.5 mo, respectively. Twenty-eight percent of patients with MCRC had poorly differentiated adenocarcinoma versus 8.6% in NMCRC patients (P = 0.028).CONCLUSION: MCRC is associated with a non-significant decrease in median survival and TTP, particularlywhen mucin content is > 75% of tumor volume. However, it tends to be more poorly differentiated. A larger study matching for stage and grade is needed. | Mirna H Farhat Kassem A Barada Ayman N Tawil Doha M Itani Hassan A Hatoum Ali I Shamseddine | 2008 | World Journal of Gastroenterology2008，14，45： | 6 |
| 2 | Eco-friendly and cleaner process for isolation of essential oil using microwave energy experimental and theoretical study显示文摘 | Farhat A Ginies C Romdhance M | 2009 | Journal of Chromatography A2009，1216，26： | 1 |
| 3 | Implicit time integration of a class of constrained hybrid formulations-part: spectral stability theory 显示文摘 | Farhat C Crivelli L Gradin M | 1995 | Computer Methods in Applied Mechanics and Engineering1995，125，1234： | 1 |
| 4 | L-Aginine reveres the adverse pregnancy changes induced by nitric oxide synthnase inhibition in the rat显示文摘 | HELMBRECHT G D FARHAT M Y LOCHBAUM L | 1996 | Am J Obstet Gynecol1996，175，4： | 1 |
| 5 | Folfox-6 combination as the first-line treatment of locally advanced and/or metastatic pancreatic cancer显示文摘 | Ghosn M Farhat F Kattan J | 2007 | Am J Clin Oncol2007，30，1： | 1 |
| 6 | Load and motion transfer algorithms for fluid/structure interaction problems with nonmatching discrete interfaces显示文摘 | Farhat C Lesoinne M LeTallec P | | 0，，： | 1 |
| 7 | The synergistic effect between erosion and corrosion of API pipeline in CO2 and saline medium显示文摘 | Aminul Islam M Farhat Zoheir N | 2013 | Tribology International2013，68，： | 1 |
| 8 | Acquired protein C deficiency in a child with acute myelogenous leukemia, splenic, renal, and intestinal infarction显示文摘 | Roula A Farah Khalil S Jalkh Hussein Z Farhat Paul E Sayad Adel M Kadri | 2011 | Blood Coagulation & Fibrinolysis2011，，2： | 1 |
| 9 | Updating finite-element dynamic models using an element-by-element sensitivity methodology显示文摘 | FARHAT C HEMEZ F M | 1993 | AIAA Journal1993，31，9： | 1 |
| 10 | Reduced maternal mor- tality in Tunisia and voluntary commitment to gender - related con- cerns显示文摘 | Ben Farhat E Chaouch M CheUi H et 81 | 2012 | International Journal of Gynecology and Obestetrics2012，116，： | 1 |
| 11 | High-speed flow visualization in a pump-turbine under off-design operating conditions显示文摘 | V Hasmatuchi S Roth F Botero F Avellan M Farhat | 2010 | IOP Conference Series: Earth and Environmental Science2010，，1： | 1 |
| 12 | Long-term invasive and noninvasive results of percutaneous balloon pulmonary valvuloplasty in children, adolescents, and adults 显示文摘 | Jarrar M Betbout F Farhat MB | 1999 | Am Heart J1999，138，51： | 1 |
| 13 | Two efficient staggered algorithms for the serial and parallel solution of three-dimensional nonlinear transient aeroelastic problems显示文摘 | Farhat C Lesoinne M | 2000 | Comput Methods Appl Mech Engrg2000，182，： | 1 |
| 14 | Two-level domain decomposition methods with Lagrange multipliers for the fast iterative solution of acoustic scattering problems显示文摘 | FARHAT C MACEDO A LESOINNE M | 2000 | Computer Methods in Applied Mechanics and Engineering2000，184，： | 1 |
| 15 | Falsepositive tuberculin skin tests: what is the absolute effect of BCG and nontuberculosis mycobacteria?显示文摘 | Farhat M Greenaway C Pai M | 2006 | Int J Tuberc Lung Dis2006，10，11： | 1 |
| 16 | Geometric conservation laws for flow problems with moving boundaries and deformable meshes and their impact on aeroelastic computations显示文摘 | Lesoinne M Farhat C | | 0，，： | 1 |
| 17 | FOLFOX-6 combination as the first-line treatment of locally advanced and/or metastatic pancreatic cancer 显示文摘 | Ghosn M Farhat F Kattan J | 2007 | Am J Clin Oncol2007，30，1： | 1 |
| 18 | Updating finite element dynamic models using an element-by-element sensitivity methodology 显示文摘 | C Farhat F M Hemez | 1993 | AIAA Journal1993，31，9： | 1 |
| 19 | Implicit time integration of a class of constrained hybrid formulations-part i: Spectral stability theory 显示文摘 | Farhat C Crivelli L Geradin M | 1995 | Computer Methods in Applied Mechanics and Engineering1995，125，1： | 1 |
| 20 | Elevated C- reactive protein and spontaneous bacterial peritonitis in children with chronic liver disease and ascites 显示文摘 | Preto-Zamperlini M Farhat SC Perandi MB | 2014 | J Pediatr Gastroenterol Nutr2014，58，1： | 1 |
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