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| 1 | Lymphomatous involvement of gastrointestinal tract: Evaluation by positron emission tomography with ^(18)F-fluorodeoxyglucose显示文摘AIM: To demonstrate the 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET) findings in patients with non-Hodgkin's lymphoma (NHL) involving the gastrointestinal (GI) tract and the clinical utility of modality despite of the known normal uptake of FDG in the GI tract.METHODS: Thirty-three patients with biopsy-proven gastrointestinal NHL who had undergone FDG-PET scan were included. All the patients were injected with 10-15 mCi FDG and scanned approximately 60 min later with a CTI/Siemens HR (+) PET scanner. PET scans were reviewed and the maximum standard uptake value (SUVmax) of the lesions was measured before and after the treatment,if data were available and compared with histologic diagnoses.RESULTS: Twenty-five patients had a high-grade lymphoma and eight had a low-grade lymphoma. The stomach was the most common site of the involvement (20 patients). In high-grade lymphoma, PET showed focal nodular or diffuse hypermetabolic activity. The average SUVmax±SD was 11.58±5.83. After the therapy,the patients whose biopsies showed no evidence of lymphoma had a lower uptake without focal lesions.The SUVmax±SD decreased from 11.58±5.83 to 2.21±0.78. In patients whose post-treatment biopsies showed lymphoma, the SUVmax±SD was 9.42±6.27. Low-grade follicular lymphomas of the colon and stomach showed diffuse hypermetabolic activity in the bowel wall (SUVmax 8.2 and 10.3, respectively). The SUVmax was 2.02-3.8 (mean 3.02) in the stomach lesions of patients with MALT lymphoma.CONCLUSION: 18F-FDG PET contributes to the diagnosis of high-grade gastrointestinal non-Hodgkin's lymphoma,even when there is the normal background FDG activity. Furthermore, the SUV plays a role in evaluating treatment response. Low-grade NHL demonstrates FDG uptake but at a lesser intensity than seen in high-grade NHL. | Sith Phongkitkarun Vithya Varavithya Toshiki Kazama Silvana C Faria Martha V Mar Donald A Podoloff Homer A Macapinlac | 2005 | World Journal of Gastroenterology2005，11，46： | 6 |
| 2 | Interleukin-6-174G/C polymorphism is associated with a decreased risk of type 2 diabetes in patients with chronic hepatitis C virus显示文摘BACKGROUND Chronic hepatitis C(CHC)is associated with type 2 diabetes mellitus.Although the pathogenesis remains to be elucidated,a growing evidence has suggested a role of pro-inflammatory immune response.Increased serum concentrations of Interleukin 6(IL-6)have been associated with insulin resistance,type 2 diabetes mellitus as well as advanced forms of liver disease in chronic hepatitis C infection.AIM To investigate the frequency of IL-6-174G/C(rs1800795)single nucleotide polymorphism(SNP)in CHC patients and in healthy subjects of the same ethnicity.Associations between type 2 diabetes mellitus(dependent variable)and demographic,clinical,nutritional,virological and,IL-6 genotyping data were also investigated in CHC patients.METHODS Two hundred and forty-five patients with CHC and 179 healthy control subjects(blood donors)were prospectively included.Type 2 diabetes mellitus was diagnosed according to the criteria of the American Diabetes Association.Clinical,biochemical,histological and radiological methods were used for the diagnosis of the liver disease.IL-6 polymorphism was evaluated by Taqman SNP genotyping assay.The data were analysed by logistic regression models.RESULTS Type 2 diabetes mellitus,blood hypertension and liver cirrhosis were observed in 20.8%(51/245),40.0%(98/245)and 38.4%(94/245)of the patients,respectively.The frequency of the studied IL-6 SNP did not differ between the CHC patients and controls(P=0.81)and all alleles were in Hardy-Weinberg equilibrium(P=0.38).In the multivariate analysis,type 2 diabetes mellitus was inversely associated with GC and CC genotypes of IL-6-174(OR=0.42;95%CI=0.22-0.78;P=0.006)and positively associated with blood hypertension(OR=5.56;95%CI=2.79-11.09;P<0.001).CONCLUSION This study was the first to show that GC and CC genotypes of IL-6-174 SNP are associated with a decreased risk of type 2 diabetes mellitus in patients chronically infected with hepatitis C virus.The identification of potential inflammatory mediators involved in the crosstalk between hepatitis C virus and the axis pancreas-liver remains important issues that deserve further investigations. | Cliviany Borges da Silva Diego Alves Vieira Luisa Freitas de Melo Anna Luiza Soares Chagas Adriana Dias Gomes César Lúcio Lopes de Faria Jr Rosangela Teixeira Dulciene Maria de Magalh?es Queiroz Gifone Aguiar Rocha Maria Marta Sarquis Soares Juliana Maria Trindade Bezerra Luciana Diniz Silva | 2020 | World Journal of Hepatology2020，12，4： | 2 |
| 3 | Procyanidins as antioxidants and tumor cell growth modulators 显示文摘 | Faria A Calhau C de Freitas V | 2006 | J Agric Food Chem2006，54，6： | 1 |
| 4 | Adsorp tion of anionic and Cationic dyes on activated carbons with different surface chemistries显示文摘 | Faria P C C (O)rafo J J M PereiraM F R | 2004 | Water Res2004，38，： | 1 |
| 5 | Computational analysis of coned-face spiral groove gas seals using the finite element method显示文摘 | Marco T C Faria | 2005 | Revue Europeenne des Elements2005，14，23： | 1 |
| 6 | Mercury contamination in farmed fish setup on former garimpo mining areas in the Northern Mato Grosso State, Amazonian region, Brazil显示文摘 | Farias R A Hacon S Campos R C | 2005 | Science of the Total Environment2005，348，13： | 1 |
| 7 | Apoptosis induced by prolonged exposure to odorants in cultured ceils from rat olfactory epithelium 显示文摘 | Brauchi S Cea C Farias JG | 2006 | Brain Res2006，1103，1： | 1 |
| 8 | Brainstem compression syndrome caused by vertebrobasilar dolichoectasia : microvascular repositioning technique 显示文摘 | Pereira-Filho A Faria M Bleil C | 2008 | Arq Neuropsiquiatr2008，66，2： | 1 |
| 9 | Plasma metalloproteinase activity is enhanced in the euglobulin fraction of breast and lung cancer patients显示文摘 | Farias E Ranuncolo S Cresta C | 2000 | Int J Cancer2000，89，4： | 1 |
| 10 | 查看详情显示文摘 | Faria A L M ac Leod T C O | | 0，，： | 1 |
| 11 | Modulation techniques to eliminate leakage currents in transformerless three-phase photovoltaic systems显示文摘 | Cavalcanti M C de Oliveira K C de Farias A M | 2010 | IEEE Transactions on Industrial Electronics2010，57，4： | 1 |
| 12 | CT evaluation of the response of gastrointestinal stromal tumors after imatinib mesylate treatment: a quantitative analysis correlated with FDG PET findings显示文摘 | Choi H Charnsangavej C de Castro Faria S | 2004 | Am J Roentgenol2004，183，6： | 1 |
| 13 | Macular alterations after small-incision cataract surgery显示文摘 | Lobo C L Faria P M Soares M A | 2004 | J Cataract Refract Surg2004，30，4： | 1 |
| 14 | Proteolytic effect of Oenococcus oeni on the nitrogenous macromolecular fraction of red wine显示文摘 | DE NARDA M C M FARIAS M E POLO M C | 1999 | FEMS Microbiol Lett1999，174，1： | 1 |
| 15 | 查看详情显示文摘 | Barros V P Faria A L M acLeod T C O | | 0，，： | 1 |
| 16 | Intrusion detection system for wireless sensor networks using danger theory immune-inspired techniques显示文摘 | Salmon H M de Farias C M Loureiro P | 2013 | International Journal of Wireless Information Networks2013，20，1： | 1 |
| 17 | Eliminating leakage currents in neutral point clamped inverters for photovoltaic systems显示文摘 | Cavalcanti M C Farias A M Oliveira K C | 2012 | IEEE Transactions on Industrial Electronics2012，59，1： | 1 |
| 18 | Synthesis and characterization of an VOPO4-polyaniline lamellar hybrid compound显示文摘 | FARIAS R FARIAS D AIROLDI C | 2003 | Solid State Sciences2003，5，4： | 1 |
| 19 | An efficient finite element procedure for analysis of high-speed spiral groove gas face seals 显示文摘 | Faria M T C | 2001 | ASME Journal of Tribology2001，123，1： | 1 |
| 20 | Assessment of 4- (5-)methylimidazole in soft drinks and dark beer显示文摘 | S C Cunha A I Barrado M A Faria et a/ | 2011 | Journal of Food Composition and Analysis2011，24，： | 1 |
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