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| 1 | Serial imaging of human embryonic stem-cell engraftment and teratoma formation in live mouse models显示文摘表示为基于 radiopharmaceutical 的成像为生物体之发光成像或 HSV1 thymidine kinase (HSV1-TK ) 编码任何一个萤火虫酶(fLuc ) 的记者 transgene 的 lentiviral 向量的二种新类型被构造监视人的胚胎的干细胞(hESC ) 在在移植以后的活老鼠的嫁接和增长。任何一个 transgene 的组成的表示没在文化改变 hESCs 的性质。我们下次在 SCID 鼠标监视了 teratomas 的形成到测试(1 ) 是否修改基因的 hESCs 维持他们的发展 pluripotency,并且(2 ) 是否支撑了记者基因表示,允许 noninvasive,在一个活鼠标模型的 hESC 衍生物的整个身体的成像。我们在接种以后从修改基因的房间以及野类型的 hESCs 2-4 月的两种类型观察了 teratoma 形成。用一个光成像系统,从 fLuc-transduced hESCs 的生物体之发光容易在在摸得出的肿瘤能被检测以前,长忍受 teratomas 的老鼠被检测。开发一个 noninvasive 成像方法对诊所更容易地可译,我们也利用了 HSV1-TK 和它的特定的底层, 1-(2 鈥 ? deoxy-2 鈥 ?fluoro- 尾 - D-arabinofuranosyl )-5-[125I]iodouracil ([125I ] FIAU ) ,记者 / 探查对。在全身的管理以后,[125I ] FIAU 是仅仅由编码 transgene 的 HSV1-TK 酶的 phosphorylated 并且在 transduced 以内保留(并且移植) 房间,由单个光子的排放允许敏感、量的成像计算了断层摄影术。象这些那样的 Noninvasive 成像方法可以使我们能在实时接受者以内重复地监视移植人的干细胞的存在和分发在上一通过记者基因的表达式长期。 | Martin G Pomper Holly Hammond Xiaobing Yu Zhaohui Ye Catherine A Foss Doris D Lin James J Fox Linzhao Cheng | 2009 | Cell Research2009，19，3： | 9 |
| 2 | Optimising islet engraftment is critical for successful clinical islet transplantation显示文摘 | O Korsgren T Lundgren M Felldin A Foss B Isaksson J Permert N H Persson E Rafael M Rydén K Salmela A Tibell G Tufveson B Nilsson | 2008 | Diabetologia2008，，2： | 2 |
| 3 | Tem- plate-synthesized nanoscopic gold particles: optical spectra and the effects of particle size and shape显示文摘 | Foss Jr C A Hornyak G L Stockert J A | 1994 | J Phys Chem1994，98，： | 1 |
| 4 | Eval- uation and development of a novel binocular treatment (I-BiT) system using video clips and interactive games to improve vision in children with amblyopia: study protocol for a randomised controlled trial显示文摘 | Foss A J Gregson R M MacKeith D | 2013 | Trials2013，14，1： | 1 |
| 5 | Ellipsometric study of the influence of chemical etching on thin porous sili- con structures显示文摘 | Selj J ThqSgersen A Foss S E | 2011 | Thin Solid Films2011，519，9： | 1 |
| 6 | Perspec- tive absorbing the concept of absorptive capacity: How to realize its potential in the organization field显示文摘 | Volberda H W Foss N J Lyles M A | 2010 | Organization Science2010，21，4： | 1 |
| 7 | Sleep, learning, and dreams: off-line memory reprocessing显示文摘 | STICKGOLD R HOBSON J A FOSSE R | 2001 | Science2001，294，： | 1 |
| 8 | Stiffness prediction of the double lap shear joint, part2: finite element modeling显示文摘 | Xiao X Foss P H Schroeder J A | 2004 | International Journal of Adhesion & Adhesives2004，24，3： | 1 |
| 9 | Absorbing the Concept of Absorptive Capacity:How to Realize Its Potential in the Organization field显示文摘 | Volberda H W Foss N J Lyles M A | 2010 | Organization Science2010，，4： | 1 |
| 10 | Multiple Model Approaches to Modeling andControl显示文摘 | T A J~ B A Foss | 1999 | International Journal of Control1999，72，78： | 1 |
| 11 | The MILS architecture for high-assurance embedded systems显示文摘 | FOSS J A HARRISON W S OMAN P | | 0，，03： | 1 |
| 12 | Template synthesis of infrared-transparent metalmicrocylinders:Comparison of optical properties with the prediction of effective mediumtheory显示文摘 | FOSS C A Jr TIERNEY M J MARTIN C R | 1992 | J Phys Chem1992，96，22： | 1 |
| 13 | Template-synthesized nanoscopic goldparticle:optical spectra and the effects of particle显示文摘 | FOSS C A Jr HORNYAK G L STOCKERT J A MARTIN C R | 1994 | J Phys Chem1994，98，11： | 1 |
| 14 | Sleep,learning,and dreams:off-line memory reprocessing显示文摘 | STICKGOLD R HOBSON J A FOSSE R | 2001 | Science2001，294，： | 1 |
| 15 | The role of external knowledge sources and organizational design in the process of opportunity exploitation 显示文摘 | Foss N J Lyngsie J Zahra S A | 2013 | Strategic Management Journal2013，34，12： | 1 |
| 16 | Radiolabeled anti-claudin 4 and anti-prostate stem cell antigen: initial imaging in experimental models of pancreatic cancer 显示文摘 | Foss C A Fox J J Feldmann G | 2007 | Molecular Imaging2007，6，2： | 1 |
| 17 | An open-label pilot study of apremilast for the treatment of moderate to severe lichen planus: a case series 显示文摘 | Paul J Foss C E Hirano S A | 2013 | J Am Acad Dermatol2013，68，2： | 1 |
| 18 | Template - Synthesized Nanoseopie Gold Particles: Optical Spectra and the Effects of Particle Size and Shape显示文摘 | C A Foss G L Hornyak J A Stockert | 1994 | J Phys Chem1994，98，： | 1 |
| 19 | Optical properties of composite membranes containing arrays of nanoscopic gold cylinders显示文摘 | Foss C A Hornyak GL Jr Stockert J A | 1992 | Phys Chem1992，96，： | 1 |
| 20 | Phase I study of the pharmacokinetics of a radioimmunoconjugate,90 Y - T101 , in patients with CD5 - expressing leukemia and lymphoma 显示文摘 | FOSS F M RAUBITSCHECK A MULSHINE J L | 1998 | Clin Cancer Res1998，4，11： | 1 |
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