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| 1 | Six-minute walking test performance is associated with survival in cirrhotic patients显示文摘BACKGROUND Patients with cirrhosis are at risk of cirrhotic cardiomyopathy,with resulting cardiac dysfunction and exercise limitations.Six minute walking test(6MWT)assesses functional status and predicts morbidity and mortality in cardiopulmonary diseases.AIM To determine if it associates with mortality by analyzing 6MWT performance in patients with liver cirrhosis.METHODS A cohort of 106 cirrhotic patients was evaluated in the outpatient setting with echocardiogram and 6MWT and follow up for one year to document hepatic decompensation and mortality.The distance in meters was recorded at the end of 6 min(6MWD).RESULTS This cohort had a mean age of 51 years and 56%male;patients were staged as Child A in 21.7%,B 66%and C 12.3%.Walk distance inversely correlated with Child scores,and was significantly reduced as Child stages progresses.Patients who died(10.4%)showed shorter mean 6MWD(P=0.006).Low 6MWD was an independent predictor of mortality(P=0.01).CONCLUSION 6MWT is a noninvasive inexpensive test whose result is related to Child scores and mortality.It is useful to identify patients with liver cirrhosis at high risk of mortality for closer monitoring and potential early intervention. | Carolina Frade M G Pimentel Ana Cristina de Castro Amaral Adriano Miziara Gonzalez Michelle Lai Danielde Oliveira Mota Maria Lucia Gomes Ferraz Wilson Mathias Junior Mario Kondo | 2021 | World Journal of Hepatology2021，13，11： | 2 |
| 2 | La2Zr2O7 formed at ceramic electrode/YSZ contacts 显示文摘 | Labrincha J A Frade J R Marques F M B | 1993 | Journal of Materials Science1993，28，： | 1 |
| 3 | Induction of cell death by endogenous nerve growth factor through its p75 receptor显示文摘 | Frade J M Rodrigue Tebar A | 1996 | Nature1996，383，6596： | 1 |
| 4 | The antigenic structure of the HIV gp120 envelope glycoprotein显示文摘 | FRADE J M LLORENTE M MELLADO M | 1997 | Clin Invest1997，，100： | 1 |
| 5 | Nitric oxide in brain: diffusion, targets and concentration dynamics in hippocampal subregions显示文摘 | Ledo A Frade J Barbosa R M | 2004 | Mol Aspects Med2004，25，12： | 1 |
| 6 | Polarization of chemokine receptors to the leading edge during lymphocyte chemotaxis显示文摘 | Nieto M Frade JM Sancho D | 1997 | Exp Med1997，186，1： | 1 |
| 7 | Protonic conduction in La2Zr2O7-based pyrochlore materials显示文摘 | Labrincha J A Frade J R Marques F M B | | 0，，1： | 1 |
| 8 | Nitric oxide in brain:diffusion,targets and concentration dynamics in hippocampal subregions显示文摘 | LEDO A FRADE J BARBOSA R M | 2004 | Mol Aspects Med2004，25，12： | 1 |
| 9 | Nitric oxide in brain:diffusion, targets and concentration dynamics in hippocampal subregions 显示文摘 | Ledo A Frade J Barbosa R M | 2004 | Molecular Aspects of Medicine2004，25，12： | 1 |
| 10 | 5-Hydroxymethylfurfural (HMF) as a building blockplatform: biological properties, synthesis and syntheticapplications显示文摘 | Rosatella A A Simeonov S P Frade R F M | 2011 | Green Chemistry2011，13，4： | 1 |
| 11 | Photo therapy promotes Healing of chronicdiabetic legulcers that failed to re spond to Other therapies 显示文摘 | Minatel D G Frade M A Franca S C | 2009 | Lasers Surgery Med2009，41，6： | 1 |
| 12 | 5-Hydroxymethylfurfural(HMF)as a building block platform:Biological properties,synthesis and synthetic applications显示文摘 | Rosatella A A Simeonov S P Frade R F M | 2011 | Green Chemistry2011，13，4： | 1 |
| 13 | Signaling through the EBV/C3d receptor (CR2,CD21) in human B lymphocyte:activation of phosphatidylinositol 3-kinase via a CD19-independent path way显示文摘 | Bouillie S Barel M Frade R | 1999 | Immunol1999，162，1： | 1 |
| 14 | Gp140,the C3d receptor显示文摘 | Frade R Barel M Ehlin Henriksson B | 1985 | Proc Natl Acad Sci USA1985，82，14： | 1 |
| 15 | 显示文摘 | Mather G C Marques F M B Frade J R | 1999 | Journal of the European Ceramic Society1999，19，： | 1 |
| 16 | Polydispersity of Hyperbranched Polyesters Based on 2,2-Bis(hydroxymethyl) propanoic Acid:SEC/MALDI-TOF MS and 13C NMR/Kinetic-Recursive Probability Analysis显示文摘 | Chikh L Tessier M Frade A | | 0，，23： | 1 |
| 17 | La2Zr2O7 Formed at Ceramic Electrode-YSZ Contacts显示文摘 | Labrincha J A Frade J R Marques F M B | 1993 | Journal of Materials Science1993，28，： | 1 |
| 18 | A novel hypothesis for Alzheimer disease based on neuronal tetraploidy induced by p75 (NTR)显示文摘 | Frade J M Lopez-Sanchez N | | 0，，10： | 1 |
| 19 | Nuelear Translocation of the p75Neu- rotrophin rqeeeptor cytoplasmic domain in response to neurotrophin binding显示文摘 | Frade J M Cajal I | 2005 | The Journal of Neuroseienee2005，25，6： | 1 |
| 20 | Toxico- logical evaluation of magnetic ionic liquids in human cell lines显示文摘 | Frade R F M Simeonov S Rosatella A A | 2013 | Chemosphere2013，92，： | 1 |
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