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| 1 | Bone mineral density in cone beam computed tomography:Only a few shades of gray显示文摘Cone beam computed tomography(CBCT) has often been used to determine the quality of craniofacial bone structures through the determination of mineral density, which is based on gray scales of the images obtained. However, there is no consensus regarding the accuracy of the determination of the gray scales in these exams. This study aims to provide a literature review concerning the reliability of CBCT to determine bone mineral density. The gray values obtained with CBCT show a linear relationship with the attenuation coefficients of the materials, Hounsfield Units values obtained with medical computed tomography, and density values from dual energy X-ray absorciometry. However, errors are expected when CBCT images are used to define the quality of the scanned structures be-cause these images show inconsistencies and arbitrari-ness in the gray values, particularly when related to abrupt change in the density of the object, X-ray beam hardening effect, scattered radiation, projection data discontinuity-related effect, differences between CBCTdevices, changes in the volume of the field of view(FOV), and changes in the relationships of size and position between the FOV and the object evaluated. A few methods of mathematical correction of the gray scales in CBCT have been proposed; however, they do not generate consistent values that are independent of the devices and their configurations or of the scanned objects. Thus, CBCT should not be considered the ex-amination of choice for the determination of bone and soft tissue mineral density at the current stage, par-ticularly when values obtained are to be compared to predetermined standard values. Comparisons between symmetrically positioned structures inside the FOV and in relation to the exomass of the object, as it occurs with the right and left sides of the skull, seem to be viable because the effects on the gray scale in the re-gions of interest are the same. | Marcio José da Silva Campos Thainara Salgueiro de Souza Sergio Luiz Mota Júnior Marcelo Reis Fraga Robert Willer Farinazzo Vitral | 2014 | World Journal of Radiology2014，6，8： | 3 |
| 2 | Adverse hepatic reactions associated with calcium carbimide and disulfiram therapy: Is there still a role for these drugs?显示文摘四乙秋兰姆化二硫和钙 carbimide 是二白酒威慑然而,广泛地在那里在酒精中毒治疗使用的狂言存在对他们的安全的大担心。hepatotoxicity 上的报告主要与四乙秋兰姆化二硫治疗有关,被出版了。钙 carbimide 的肝毒素的潜力是很好描绘的更少。这里,我们描述与被提交到 hepatotoxicity 的一张注册表并且当规定这些混合物时,指出我们面对的限制的这个治疗学的组有关的肝损坏的四个案例。对在白酒依赖的管理的这些混合物的角色的重估清楚地被需要。 | Carmen Verge M Isabel Lucena Enrique López-Torres M José Puche-García Enrique Fraga Manuel Romero-Gomez Raúl J Andrade | 2006 | World Journal of Gastroenterology2006，12，31： | 2 |
| 3 | A human ESC model for MLL-AF4 leukemic fusion gene reveals an impaired early hematopoietic-endothelial specification显示文摘MLL-AF4 熔化基因是在在婴儿的高风险的尖锐成淋巴细胞的白血病的一个特点 genomic 错误。尽管 MLL-AF4 在人的开发期间出生前地产生,这很好被建立,它在在 utero 的造血的开发的效果仍然保持未经勘探。我们创造了一个人特定的细胞的系统在 MLL-AF4-expressing 人的胚胎的干细胞(hESCs ) 学习早 hemato-endothelial 开发。介绍的功能的研究,同种细胞的分析和基因表示表明在 hESCs 的 MLL-AF4 的那表情有 phenotypic,功能并且基因表示影响。MLL-AF4 在 hESCs 充当全球 transcriptional 使活跃之物和 homeobox 基因表示的一个积极管理者。机能上地, MLL-AF4 从 hESCs 提高 hemogenic 先锋的说明,但是强烈损害进一步造血的承诺赞成 endothelial 房间命运。MLL-AF4 hESCs transcriptionally 被告知向对 endothelial 成熟敏感的 hemogenic 先锋区分,由联系到 vascular-endothelial 功能和早造血作用的主人基因的显著 upregulation 思考了。而且,我们报导那 MLL-AF4 表情不是足够的转变导出 hESC 的造血的房间。这个工作说明 hESCs 怎么可以提供唯一的卓见进人的开发并且推进我们理解白血病的熔化基因,知道出生前地产生,调整人的胚胎的造血的说明。 | Clara Bueno Rosa Montes Gustavo J Melen Verdnica Ramos-Mejia Pedro J Real Ver6nica Ayllo'n Laura Sanchez Gertmdis Ligero Inmaculada Gutierrez-Aranda Agustin F Femfindez Mario F Fraga Inmaculada Moreno-Gimeno Deborah Btlrks Maria del Carmen Plaza-Calonge Juan C Rodriguez-Manzaneque Pablo Menendez | 2012 | Cell Research2012，22，6： | 2 |
| 4 | Comparison of sexualand drug use behaviors between female sex workers in Tijuanaand Ciudad Juarez, Mexico显示文摘 | Patterson T 1 Semple S J Fraga M | 2006 | Substance Use & Misuse y2006，41，1012： | 1 |
| 5 | Empirical studies of the spreading of oil spills显示文摘 | Lehr W J Cekirge H M Fraga J | 1984 | Oil and Petrochemical Pollution1984，2，： | 1 |
| 6 | Empirical Studies of the Spreading of Oil Spills显示文摘 | LEHR W J CEKIRGE H M FRAGA R J | 1984 | Oil and PetrochemicalPollution1984，2，1： | 1 |
| 7 | Primary extramedullary myeloid tumor of the breast:a case report and review of the literature显示文摘 | Quintas Cardama A Fraga M A ntunez J | 2003 | Ann Hemato l2003，82，7： | 1 |
| 8 | Ultrastructural evidence of increased tolerance of hibernating myocardium to cardioplegic ischemia-reperfusion injury显示文摘 | Milei J Fraga CG Grana DR | 2004 | J Am Coll Cardiol2004，43，12： | 1 |
| 9 | Pathological role of interleukin 17 in mice subjected to repeated BCG vaccination after infection with Mycobacterium tuberculosis显示文摘 | CRUZ A FRAGA A G FOUNTAIN J J | | 0，，8： | 1 |
| 10 | A New Technique to estimate initial spill size using a modified Fay-Type spreading formula显示文摘 | Lehr W J Fraga R J Belen M S | 1984 | Marine Pollution Bulletin1984，15，9： | 1 |
| 11 | The ADAMTS12 metal- loprotease gene is epigenetically silenced in tumor cells and transcrip- tionally activated in the stroma during progression of colon cancer 显示文摘 | Moneada-Pazos A Obaya A J Fraga ME | 2009 | J Cell Sei2009，122，16： | 1 |
| 12 | Ecofriendly fast sythesis of hydrophilie poly(ehhyleneglyeol)-ionic liquid matrices for liquid-phase organic synthesis 显示文摘 | FRAGA D J FAMELART M BAZUREAU J P | 2002 | Org Process Res Dev2002，6，4： | 1 |
| 13 | Smoking and low antioxidant levels increase oxidative damage to sperm DNA 显示文摘 | Fraga CG Motchnik PA Wyrobek A J | 1996 | Mutat Res1996，351，2： | 1 |
| 14 | Humics as an electron donor for anaerobic respiration显示文摘 | Lovley D R Fraga J L Coates J D | 1999 | Environ Microbiol1999，1，1： | 1 |
| 15 | Antibacterial Effects of Endodontic Irrigants on Black-pigmented Gram-negative Anaerobes and Facultative Bacteria显示文摘 | Siqueira J F Batista M Fraga R | 1998 | Journal of Endodontics1998，24，6： | 1 |
| 16 | Acute generalized exanthematous pustulosis in patients receiving high -dose chemotherapy显示文摘 | Fraga J Munoz E | 1999 | Arch Dermatol1999，135，11： | 1 |
| 17 | Empirical studies of the spreading of oil spills显示文摘 | Lehr W J Cekirge H M Fraga R J | 1984 | Oil and Petro Chemical Pollution1984，2，： | 1 |
| 18 | Detection of Toxoplasma gondii in eerebrnspinal fluid from AIDS patients by nested PCR and rapid identification of type I allele at B1 gene by RFLP analysis显示文摘 | Alfi)nso Y Fraga J Jimb:nez N et cd | 2009 | Exp Parasitol2009，122，3： | 1 |
| 19 | Why don't all heavy snorers have obstructive sleep apnea显示文摘 | Polo O J Taftl M Fraga J | 1991 | Am Rev Respir Dis1991，143，6： | 1 |
| 20 | Bronchoscope and tracheotomy removal of bronchial foreign body显示文摘 | Fraga J C Neto A M Seitz E | 2002 | J Pediatr Surg2002，37，8： | 1 |
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