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| 1 | Migration-associated secretion of melanoma inhibitory activity at the cell rear is supported by KCa3.1 potassium channels显示文摘恶意的黑瘤,由侵略本地生长和转移的早形成描绘了,是皮癌症的最好攻击的类型。黑瘤禁止的活动(MIA ) ,由恶意的黑瘤房间藏匿了,与房间粘附受体, integrins 伪 4 尾 1 和伪 5 尾 1,便于的房间分开和转移的支持的形成交往。在现在的学习,我们证明那 MIA 分泌物被限制到移植房间的后面的目的,当在非移居的房间 MIA 在肌动朊外皮积累时。MIA 蛋白质包括上衣蛋白质建筑群拿一条常规能分泌的小径我(COPI )- 并且上衣蛋白质建筑群 II (COPII ) 依赖者蛋白质运输到房间圆周,在它的最后的版本取决于细胞内部的 Ca2+ 离子的地方。有趣地,激活 Ca2+ 的 K+ 隧道,亚科 N,成员 4 (KCa3.1 ) ,知道在移植房间的后面的结束活跃,被发现支持 MIA 分泌物。分泌物被特定的 KCa3.1 隧道禁止者 TRAM-34 并且由隧道的主导否定的异种的表示减少。在摘要,我们阐明了到房间尾部并且也的 MIA 蛋白质的联系迁居的运输揭示了 KCa3.1 钾隧道由支持房间移植的新机制。 | Jennifer Schmidt Kristin Friebel Roland Schoenherr Marc G Coppolino Anja-Katrin Bosserhoff | 2010 | Cell Research2010，20，11： | 3 |
| 2 | Determination of optical properties of human blood in the spectral range 250 to 1100 nm using Monte Carlo simulations with hematocrit-dependent ef- fective scattering phase functions显示文摘 | Friebel M Roggan A Muller G | 2006 | J Biomed Opt2006，11，34： | 1 |
| 3 | Career Concerns in Teams 显示文摘 | Auriol E Friebel G Pechlivanos L | 2002 | Journal of Labor Economics2002，，20： | 1 |
| 4 | Fiber grating sensors 显示文摘 | A D Kersey M A Davis H J Patrick M LeBlanc K P Koo C G Askins M A Putnam E J Friebele | 1997 | Lightwave Technology1997，15，8： | 1 |
| 5 | Fabrication of Tapered Strain Gradient Chirped Fiber BraggGratings 显示文摘 | Williams G M Friebele E J | 1995 | ElectronLett1995，31，4： | 1 |
| 6 | Fiber grating sensors显示文摘 | KERSEY A D DAVIS M A PATRICK H J LeBLANC M KOO K P ASKINS C G PUTNAM M A FRIEBELE E J | 1997 | Journal Lightwave Technology1997，15，8： | 1 |
| 7 | Space irradiation effects on erbium-doped fiber devices: sources, amplifiers, and passive measurements 显示文摘 | Williams G M Friebele E J | 1998 | IEEE Transactions on Nuclear Science1998，45，3： | 1 |
| 8 | Home Range and Habitat Use of Feral Hogs in Congaree National Park, South Carolina 显示文摘 | Friebel B A Jodice P G R | 2009 | Human Wildlife Conflicts2009，3，： | 1 |
| 9 | Structural basis for the reversible activation of a Rho protein by the bacterial toxin SopE 显示文摘 | Buchwald G Friebel A Galan JE | 2002 | EMBO J2002，21，13： | 1 |
| 10 | Defect centers in a germanium doped silica core optical fiber显示文摘 | FRIEBELE E J GRISCOM D L SIGEL G H | 1974 | Journal of Applied Physics1974，45，8： | 1 |
| 11 | Fiber Grating Sensors显示文摘 | Kersey A D Davis M A Patrick H J LeBlanc M Koo K P Askins C G Putnam M A and Friebele E J | 1997 | J of Lightwave Technology1997，15，8： | 1 |
| 12 | An analysis of photobleaching tech- niques for the radiation hardening of fiber optic da'ta links显示文摘 | SIGEL G H Jr FRIEBELE E J MARRONE M J | 1981 | IEEE Transactions on Nuclear Science1981，28，6： | 1 |
| 13 | Overview of radiationeffects in fiber optics 显示文摘 | FRIEBELE E J LONG K J ASKINS C G | 1985 | SPIE1985，541，： | 1 |
| 14 | Optical fiber waveguides in radiation environments显示文摘 | FRIEBELE E J ASKINS C G GINGERICH M E | 1984 | Nuclear Instruments and Methods in Physics Research1984，1，： | 1 |
| 15 | Optical Fiber Sensors for Spacecraft Applications显示文摘 | Friebele E J Askins C G Kersey A B | 2000 | Smart Materials and Structures2000，，4： | 1 |
| 16 | Space radiation effects on erbium-doped fibers显示文摘 | WILLIAMS G M PUTNAM M A FRIEBELE E J | 1996 | SPIE1996，2811，： | 1 |
| 17 | Correlation of sin-gle-mode fiber radiation response and fabrication parameters显示文摘 | Friebele E J Askins C G Shaw C M | 1991 | Applied Optics1991，30，15： | 1 |
| 18 | Fiber grating sensors显示文摘 | Kersey A D Davis M A Patrick H J LeBlanc M Koo K P Askins C G Putnam M A Friebele E J | | 0，，08： | 1 |
| 19 | Determination of optical properties of human blood in the spectral range 250 to 1100 nm using Monte Carlo simulations with hematocrit-dependent'effective scattering phase functions 显示文摘 | Friebel M Roggan A MUller G | 2006 | J Biomed Opt2006，11，3： | 1 |
| 20 | Distributed strain sensing with fiber Bragg grating array embedded in CRTM composites显示文摘 | Atkins C G Putnam M A | 1994 | Electron Lett1994，30，21： | 1 |
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