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| 1 | Nonalcoholic fatty liver disease in patients with inflammatory bowel disease: Beyond the natural history显示文摘BACKGROUND Nonalcoholic fatty liver disease(NAFLD)is a frequently reported condition in patients with inflammatory bowel disease(IBD).Both intestinal inflammation and metabolic factors are believed to contribute to the pathogenesis of IBDassociated NAFLD.AIM To evaluate the prevalence of steatosis and liver fibrosis(LF)in a cohort of IBD patients and the identification of metabolic-and IBD-related risk factors for NAFLD and LF.METHODS IBD patients were consecutively enrolled from December 2016 to January 2018.Demographic,anthropometric and biochemical data were collected so as eating habits.Abdominal ultrasound and transient elastography were performed to evaluate the presence of NAFLD and LF respectively.RESULTS A total of 178 consecutive patients were enrolled and included in the analysis(95 Ulcerative colitis,83 Crohn’s disease).NAFLD was detected by imaging in 72(40.4%)patients.Comparison between patients with and without NAFLD showed no significant differences in terms of IBD severity,disease duration,location/extension,use of IBD-related medications(i.e.,steroids,anti-TNFs,and immunomodulators)and surgery.NAFLD was significantly associated with the presence of metabolic syndrome[MetS;odds ratio(OR):4.13,P=0.001]and obesity defined by body mass index(OR:9.21,P=0.0002).IBD patients with NAFLD showed higher caloric intake and lipid consumption than those without NAFLD,regardless disease activity.At the multivariate analysis,male sex,advanced age and high lipid consumption were independent risk factors for the development of NAFLD.An increased liver stiffness was detected in 21 patients(16%)and the presence of MetS was the only relevant factor associated to LF(OR:3.40,P=0.01).CONCLUSION In this study,we demonstrate that risk factors for NAFLD and LF in the IBD population do not differ from those in the general population. | Salvatore Magrì Danilo Paduano Fabio Chicco Arianna Cingolani Cristiana Farris Giovanna Delogu Francesca Tumbarello Mariantonia Lai Alessandro Melis Laura Casula Massimo C Fantini Paolo Usai | 2019 | World Journal of Gastroenterology2019，25，37： | 8 |
| 2 | Testing significance of incongruence显示文摘 | Farris JS M Kllersj AG Kluge and C Bult | 1995 | Cladistics1995，10，： | 1 |
| 3 | Acute toxicity of six freshwater mussel species (glochidia) to six chemicals: implications for Daphnids and Utterbackia imbeciUis as surrogates for protection of freshwater mussels (unionidae) 显示文摘 | Milam C D J L Farris F J Dwyer | 2005 | Arch Environ Contam Toxicol2005，48，2： | 1 |
| 4 | Granular carbon molecular sieves显示文摘 | Braymer T A Coe C G Farris T S | | 0，，： | 1 |
| 5 | Design and fabrication of two layer anti-reflection coatings for optical amplifiers显示文摘 | BUUS J KEARLEY M | 1990 | IEEE Electron LETT1990，26，19： | 1 |
| 6 | Knowledge management in research and development显示文摘 | Armbrecht Jr.F M Ross Chappelow C C Farris G F | | 0，，04： | 1 |
| 7 | Control of the complement system显示文摘 | Liszewski M K farries T C Lublin D M | 1996 | Adv Immunol1996，61，2： | 1 |
| 8 | Biomarker and bioaccumulation responses of Asian Clams exposed to aqueous Cadium 显示文摘 | BARFIELD M L FARRIS J L BLACK M C | 2001 | Journal of Toxicology and Environmental Health2001，63，7： | 1 |
| 9 | Cost impact of molecular testing for indeterminate thyroid nodule fine-needle aspiration biopsies 显示文摘 | Yip L Farris C Kabaker AS | 2012 | J Clin Endocrinol Metab2012，97，6： | 1 |
| 10 | Very Broad Reflection Bandwidth (44 nm) Chirped Fiber Gratings andNarrow Bandpass Filter Produced by the Use of an Amplitude Mask 显示文摘 | Sugden C T | 1994 | Electron Lett1994，30，11： | 1 |
| 11 | Impact on the clinical out- come of prostate cancer by the 2005 International Society of Urolog- ical Pathology modified Gleason grading system 显示文摘 | Dong F Wang C Farris AB | 2012 | Am J Surg Pathol2012，36，6： | 1 |
| 12 | The postero- lateral corner of the knee: Repair versus reconstruction显示文摘 | STANNARD J P BROWN S L FARRIS R C | 2005 | Am J Sports Med2005，33，6： | 1 |
| 13 | Preoperative stent place- ment decreases cost of ureteroscopy显示文摘 | Chu L Farris C A Corcoran A T | 2011 | Urology2011，7，8： | 1 |
| 14 | Work-family conflict and turnover intentions among scientists and engineers working in R&D显示文摘 | Post C Ditomaso N Farris G F Cordero R | 2009 | Journal of business psychology2009，24，1： | 1 |
| 15 | Impact on the clinical outcome of prostate cancer by the 2005 international society of urological pathology modified Gleason grading system显示文摘 | Dong F Wang C Farris AB | 2012 | Am J Surg Pathol2012，36，6： | 1 |
| 16 | Finite element analysis of the mechanics of blade/disk contacts显示文摘 | Gean M C Farris T N | 1907 | AIAA-2005-1907，2005，： | 1 |
| 17 | Biomarker and bioaccumulation responses of asian clams exposed to aqueous cadmium 显示文摘 | Barfield M L Farris J L Black M C | 2001 | Journal of Toxicology and Envi- ronmental Health2001，63，7： | 1 |
| 18 | TNT, a free program for phylogenetic analysis显示文摘 | Goloboff P A Farris J S Nixon K C | 2008 | Cladistics2008，24，5： | 1 |
| 19 | Work - family conflict and turnover intentions among scientists and engineers working in R&D 显示文摘 | Post C DiTomaso N Farris G F Cordero R | 2009 | Journal of Business Psychology2009，24，1： | 1 |
| 20 | An analytical management framework for new product development processes featuring uncertain iterations显示文摘 | Martínez León H C Farris J A Letens G | 2013 | Journal of Engineering and Technology Management2013，30，1： | 1 |
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