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| 1 | 血浆游离DNA水平增高可作为预测重型颅脑损伤患者死亡率的独立指标(英文)显示文摘Trauma is the leading cause of death under 45 years worldwide and up to 50% of trauma fatalities are due to brain injury.Prediction of outcome is one of the major problems associated with severe TBI and research efforts have focused on the investigation of biomarkers with prognostic value following TBI. Therefore,our aim was to investigate whether cell-free DNA concentrations correlated to short-term primary outcome( survivor or death) and GCS scores following severe TBI. A total of 188 victims of severe TBI were enrolled in this prospective study,outcome variables comprised: survival and neurological assessment using the GCS at ICU discharge. Control blood samples were obtained from 25 healthy volunteers. Peripheral venous blood was collected at admission in the ICU. Plasma DNA was measured using a real-time quantitative PCR assay for the β-globin gene. There was correlation between higher DNA levels and both fatal outcome and lower hospital admission GCS scores. Plasma DNA concentrations at the chosen cut- off point( ≥171,381 kilogenomesequivalents /L) predicted mortality with a specificity of 90% and a sensitivity of 43%. Logistic regression analysis showed that elevated plasma DNA levels were independently associated with death( P < 0. 001). In conclusion,high cell-free DNA concentration was a predictor of short-term mortality following severe TBI. | Rodrigues Filho EM1 Simon D Ikuta N Klovan C Dannebrock F de Oliveira CO Regner A | 2014 | 中华神经外科疾病研究杂志2014，13，3： | 6 |
| 2 | Posterior partially edentulous jaws, planning a rehabilitation with dental implants显示文摘AIM: To discuss important characteristics of the useof dental implants in posterior quadrants and the rehabilitation planning. METHODS: An electronic search of English articles was conducted on MEDLINE(PubM ed) from 1990 up to the period of March 2014. The key terms were dental implants and posterior jaws, dental implants/treatment planning and posterior maxilla, and dental implants/treatment planning and posterior mandible. No exclusion criteria were used for the initial search. Clinical trials, randomized and non randomized studies, classical and comparative studies, multicenter studies, in vitro and in vivo studies, case reports, longitudinal studies and reviews of the literature were included in this review. RESULTS: One hundred and fifty-two articles met the inclusion criteria of treatment planning of dental implants in posterior jaw and were read in their entirety. The selected articles were categorized with respect to their context on space for restoration, anatomic considerations(bone quantity and density), radiographic techniques, implant selection(number, position, diameter and surface), tilted and pterygoid implants, short implants, occlusal considerations, and success rates of implants placed in the posterior region. The results derived from the review process were described under several different topic headings to give readers a clear overview of the literature. In general, it was observed that the use of dental implants in posterior region requires a careful treatment plan. It is important that the practitioner has knowledge about the theme to evaluate the treatment parameters. CONCLUSION: The use of implants to restore the posterior arch presents many challenges and requires a detailed treatment planning. | Douglas R Monteiro Emily V F Silva Eduardo P Pellizzer Osvaldo Magro Filho Marcelo C Goiato | 2015 | World Journal of Clinical Cases2015，3，1： | 6 |
| 3 | An automated system for liquid - liquid extraction based on a new micro - batch extraction chamber with on - line detection Preconcentration and determination of copper ( Ⅱ ) 显示文摘 | DINIZ M C T FILHO O F ROHWEDDER J J R | 2004 | Anal Chim Acta2004，525，2： | 1 |
| 4 | Comparison of three single-phase PLL algorithms for UPS applications显示文摘 | Santos Filho R M Seixas P F Cortizo P C | 2008 | IEEE Transactions on Industrial Electronics2008，55，8： | 1 |
| 5 | Posttransplant Diabetes Mellitus: Incidence and Risk Factors 显示文摘 | Mazali F C Lalli C A Filho G A | 2008 | Transplant Proc2008，40，4： | 1 |
| 6 | Re-Os and Sm-Nd isotope and trace element constraints on the origin of the chromite deposit of the Ipueira-Medrado Sill, Bahia, Brazil 显示文摘 | Marques J C Ferreira Filho C F Carlson R W | 2003 | Journal of Petrology2003，44，4： | 1 |
| 7 | Targeting key alteration minerals in epithermal deposits in Patagonia,Argentina,using ASTER imagery and principal component analysis显示文摘 | Crosta A P Souza Filho C R Azevedo F Brodie C | | 0，，21： | 1 |
| 8 | Immobilization of ethylene sulfide in aminated cellulose for removal of the divalent cations显示文摘 | Silva Filho E C Lima L C B Silva F C | 2013 | Carbohydrate polymers2013，92，2： | 1 |
| 9 | Cyclooxygenase- 2 and epidermal growth factor receptor expressions in different histological subtypes of cervical carcinomas显示文摘 | Baltazar F Filho AL Pinheiro C | 2007 | Int I Gynecol Pathol2007，26，3： | 1 |
| 10 | Thermophysical properties of biodiesel and related systems: (liquid+liquid) equilibrium data for soybean biodiesel 显示文摘 | MAZUTT! M A VOLL F A P FILHO L C | 2013 | The Journal of Chemical Thermodynamics2013，58，： | 1 |
| 11 | Tissue engineering a complete vaginal replacement from a small biopsy of autologous tissue显示文摘 | DE FILIPPO R E BISHOP C E FILHO L F | 2008 | Transplantation2008，86，2： | 1 |
| 12 | Electrophysiological effects of guanosine and MK-801 in a quinolinic acid-induced seizure model 显示文摘 | Torres F V Da Silva Filho M Antunes C | 2010 | Exp Neurol2010，221，2： | 1 |
| 13 | Experimental evaluation of fuzzy controllers for the temperature control of the secondary refrigerant in a liquid chiller显示文摘 | Silva F V Filho L C N Silveira V | 2006 | Journal of Food Engineering2006，75，3： | 1 |
| 14 | Lower uterine segment thickness measure-ment in pregnant women with previous Cesarean sec-tion:reliability analysis using two and three-dimen-sional transabdominal and transvaginal ultrasound显示文摘 | Martins W P Barra D A Gallarreta F M'Nastri C 0 Filho F M | 2009 | Ultrasound Obstet Gynecol2009，33，： | 1 |
| 15 | Sorafenib in combination with capecitabine: an oral regimen for patients with HER2-negative locally advanced or metastatic breast cancer 显示文摘 | Baselga J Segalla JG Roch6 H Del Giglio A Pinczowski H Ciruelos EM Filho SC G6mez P Van Eyll B Bermejo B Llombart A Garicochea B Durdn Md Hoff PM Espi6 M de Moraes AA Ribeiro RA Mathias C Gil Gil M Ojeda B Morales J Kwon Ro S Li S Costa F | 2012 | J Clin Oncol2012，30，13： | 1 |
| 16 | Immunohistochemical expression and distribution of VEGFR-3 in malignant mesothelioma 显示文摘 | Filho AL Bahazar F Bedrossian C | 2007 | Diagn Cytopathol2007，35，： | 1 |
| 17 | Numerical model of electromagnetic stirring for continuous casting billets 显示文摘 | Trindade L B Vilela A C F Filho A F F | 2002 | IEEE Transactions on Magnetics2002，38，6： | 1 |
| 18 | Modeling of a bipedal locomotor using coupled nonlinear oscillators of van der Pol显示文摘 | Durra M S de Filho P A C Romano V F | 2003 | Biol Cybern2003，88，4： | 1 |
| 19 | A systematic approach for structuring exception handling in robust component-based software 显示文摘 | FILHO F C GUERRA P A PAGANO V A | 2005 | Joumal of the Brazilian Computer Society2005，3，10： | 1 |
| 20 | Fuzzy uncertainty modeling applied to AP1000 nuclear power plant LOCA显示文摘 | Guimaraes A C F Lapa C M F Filho F F L S | 2011 | Annals of Nuclear Energy2011，38，8： | 1 |
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