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60篇 您的检索式:作者名="Foresta E"
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1迟发性性腺功能减退症与骨化二醇的关系显示文摘男性迟发性性腺功能减退症是指具有血清睾酮(T)水平降低和典型临床症状的综合征。而血清睾酮浓度是否总能真实反应Leydig细胞的功能目前仍不确定。轻度睾丸改变只有通过检测额外的生化标记物如黄体生成素(LH)和25.羟维生素D才能确诊。这些标记物可以帮助诊断称之为“亚临床”型的性腺功能减退(血清睾酮正常,LH升高)。性腺功能减退患者通常由于睾丸中CYP2Rt羟化酶受损而具有较低水平的25.羟维生素D。然而,目前仍无证据阐释维生素D3亦或骨化二醇是治疗此类病人的最佳选择。因此我们分析了26位具有典型性腺功能减退患者(总T[TT]〈12nmol 1^-1,LH≥8IU 1^-1)及46位亚临床型性腺功能减退患者(TT≥12nmol 1^-1,LH≥8IU 1^-1)以及低25-羟维生素D患者(〈50nmol 1^-1)。其中20名患者接受每周5000IU的维生素D3治疗,46名患者接受每周4000IU的骨化二醇治疗。治疗3个月后,患者25-羟维生素D及甲状旁腺激素升高。在两组患者中(原发型16人,亚临床型30人)补充骨化二醇可以显著提高25-羟维生素D水平并显著降低甲状旁腺激素水平,而补充维生素D3的患者,其25-羟维生素D和甲状旁腺激素水平并无明显变化。本研究首次阐述服用骨化二醇而非维生素D3,可以提高男性迟发性性腺功能减退患者25-羟维生素D水平。Carlo Foresta Aldo E Calogero Francesco Lombardo Andrea Lenzi Alberto Ferlin 2015Asian Journal of Andrology2015,17,2:2
2Prognostic Value of Y deletion analysis The role of current methods显示文摘Foresta C Moro E Ferlin A 2001Hum Reprod2001,16,8:1
3Y chromosome microdeletions and alterations of spermatogenesis显示文摘Foresta C Moro E Ferlin A 2001Endocr Rev2001,22,2:1
4Microdeletion of chromosome Y in male infertility:role of the DAZ gene显示文摘Foresta C Ferlin A Moro E 2001Ann Ital Med Int2001,16,2:1
5Deletion and expression analysis of AZFa genes on the humanY chromosome revealed amajor role for DBY inmale infertility 显示文摘Foresta C Ferlin A Moro E 2000Hum Mol Genet2000,9,8:1
6Y chromosome microdeletions and alterations of spermatogenesis 显示文摘Foresta C Moro E Ferlin A 2001Endocr Rev2001,22,2:1
7Y chromosome microdeletions in cryptorchidism and idiopathic infertility 显示文摘Foresta C Moro E Garolla A 1999J Clin Endocrinol Metab1999,84,:1
8Y chromosome microdeletions and alterations of spermatogenesis显示文摘Foresta C Moro E Ferlin A 2001Endocr Rev2001,22,2:1
9Y chromosome microdeletions and alterations of spermatogenesis显示文摘Foresta C Moro E Ferlin A 2001Endocrinol Rev2001,22,2:1
10Sertoli cell function in infertile patients with and without microdeletions of the azoospermia factors on the Y chromosome long arm 显示文摘Foresta C Bettella A Moro E 2001Clin Endocrinol Metab2001,86,6:1
11Y chromosome microdeletions and alterations of spermatogenesis 显示文摘FORESTA C MORO E FERLIN A 2001Endocrine Reviews2001,22,2:1
12Deletion and expression analysis of AZFa genes on the humanY chromosome revealed a major role for DBY in male infertility显示文摘Foresta C Ferlin A Moro E 2000Hum Mol Genet2000,9,8:1
13Prognostic value of Y deletion analysis-The role of current methods 显示文摘Foresta C Moro E Ferlin A 2001Hum Report2001,16,8:1
14Y chromosome microdeletions and alteration of spermatogenesis显示文摘Foresta C Moro E Ferlin A 2001Endor rev2001,22,2:1
15Role of the AZFa candidate genes in male infertility显示文摘Foresta C Moro E Rossi A 2000J Endocrinol Invest2000,23,10:1
16Role of the AZFa candidate genes in male infertility 显示文摘Foresta C Moro E Rossi A 2000J Endocrinol Invest2000,23,10:1
17Deletion and expressiom analysis of AZFa genes on the human Y chromosome revealed a major role for DBY in male infertility显示文摘Foresta C Ferlin A Moro E 2000Hum Mol Genet2000,9,8:1
18Y chromosome microdeletions in cryptorchidism and idiopathic infertility 显示文摘Foresta C Moro E Garolla A 1999J Clin Endocrinol Metab1999,84,:1
19Microdeletions of the Y chromosome in cryptorchidism and in idiopathic male inferyility 显示文摘Foresta C Ferlin A Moro E 1999Ann Ital Med Int1999,14,3:1
20Prognostic value of Y deletion analysis -The role of current methods 显示文摘Foresta C Moro E Ferlin A 2001Hum Reprod2001,16,8:1
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