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| 1 | Differing profiles of people diagnosed with acute and chronic hepatitis B virus infection in British Columbia,Canada显示文摘AIM To describe the characteristics of people diagnosed with acute and chronic hepatitis B virus(HBV) infection in British Columbia(BC).METHODS We used data from the BC Hepatitis Testers Cohort(BCHTC),which includes all individuals tested for hepatitis C virus(HCV) or human immunodeficiency virus(HIV) or those diagnosed with HBV or active tuberculosis in BC since 1990.These data were integrated with prescription drug,medical visit,hospitalization and mortality data.HBV cases were classified as acute or chronic according to provincial guidelines.We compared characteristics of individuals by HBV infection group(acute,chronic and negative).Factors associated with acute or chronic HBV infection were assessed with multinomial logistic regression models in comparison to the HBV negative group.RESULTS46498 of the 1058056 eligible BC-HTC participants were diagnosed with HBV infection.4.3% of HBV positive individuals were diagnosed with acute HBV infections while 95.7% had chronic infections.Problematic alcohol use,injection drug use,and HIV or HCV co-infection were more common among individuals diagnosed with acute HBV compared to those with chronic infections and HBV negative individuals.In multivariable multinomial logistic regression models,we observed significant associations between acute or chronic HBV diagnosis and being male,age at HBV diagnosis or birth cohort,South and East Asian ethnicity,HCV or HIV infection,and injection drug use.The odds of acute HBV decreased with increasing age among people who inject drugs,while the opposite was true for chronic HBV.Persons with acute HBV were predominantly White(78%) while those with chronic HBV were mostly East Asian(60%).Relative to Whites,East Asians had 12 times greater odds of being diagnosed with chronic HBV infection.These odds increased with increasing socioeconomic deprivation.CONCLUSION Differences in the profiles of people diagnosed with acute and chronic HBV infection necessitate differentiated screening,prevention,care and treatment programs. | Mawuena Binka Zahid A Butt Stanley Wong Mei Chong Jane A Buxton Nuria Chapinal Amanda Yu Maria Alvarez Maryam Darvishian Jason Wong Gina McGowan Mikhail Torban Mark Gilbert Mark Tyndall Mel Krajden Naveed Z Janjua | 2018 | World Journal of Gastroenterology2018，24，11： | 3 |
| 2 | Effect of phtosterols and phtostanols on the solubilization of cholesterol by dietary mixed micelles: An in vitro study显示文摘 | Mel'nikov S M Seiien Ten Hoorn J W M Eijkelenboom A P A M | 2004 | Chemistry and Physics of Lipids2004，127，： | 1 |
| 3 | Investigation of the Mg-Zn-Y system 显示文摘 | Padezhnova E M Mel'nik E V Miliyevskiy R A | 1982 | Russ Metall1982，，4： | 1 |
| 4 | Stochastic Analysis and the Pricing of Derivative Securities显示文摘 | Mel'nikov A V | 1999 | American Mathematical Society1999，，1： | 1 |
| 5 | Semi-transparent chitosan-TiO2 nanotubes composite film forfood package applications显示文摘 | Díaz-Visurraga J Meléndrez M F García A | 2010 | ournal of Applied Poly-mer Science2010，116，6： | 1 |
| 6 | Cervicalcytology of atypical squamous cells cannot exclude high-gradesquamous exclude high-grade squamous intraepithelial lesion(ASC-H) : histological results and recurrence after a Loopelectrosurgical excision procedure 显示文摘 | Norgara P R B Manfroni L A R Consolaro MEL | 2011 | Arch Gynecol Obstet2011，284，4： | 1 |
| 7 | Porous hydroxyapatite for artifical bone applications显示文摘 | Sopyan I Mel M Ramesh S Khalid K A | 2007 | Science and Technology of Advanced Materials2007，8，1： | 1 |
| 8 | Involvement of primary mesenchymal precursors and hematopoietic bone marrow cells from chronic myeloid leukemia patients by BCR‐ABL1 fusion gene显示文摘 | Mauricio Chandia José-María Sayagués María-Laura Gutiérrez María-Carmen Chillón José-Alejandro Aristizábal Alejandro Corrales Marta Castellanos Alberto Melón María-Luz Sánchez Paloma Bárcena Sergio Matarraz María González‐González Susana Barrena Antonio L | 2014 | Hematol2014，，3： | 1 |
| 9 | Employability:a psycho-social construct,its dimensions,and applications显示文摘 | FUGATE MEL KINICKI A J ASHFORTH B E | 2004 | Journal of Vocational Behavior2004，，65： | 1 |
| 10 | Efficacy of lamivudine in patients with hepatits B virus precore mutant infection before and after liver transplantation显示文摘 | Ben Ari Z Ze mel R Kazetsker A | 1999 | Am J Gastroenterol1999，94，3： | 1 |
| 11 | Ex-traction of boron compounds from natural waste-water and in-dustrial effluents 显示文摘 | PILIPENKO A T GREBENYUK V D MEL NICK L-A | 1990 | Khimiyai Tekhnologuiya Vody1990，12，： | 1 |
| 12 | 显示文摘 | Chirkin A P Demyanets L N Doronin S N Genkina E A Ivanov-Shits A K Kondratyuk I P Maksimov B A Mel'Nikov O K Muradyan L N Simonov V I Timofeeva V A Superionic conductors Li3M2(PO4)3 (M=Fe Sc Cr): Synthesis structure and electrophysical properties | 1990 | Solid State Ionics1990，38，： | 1 |
| 13 | Hepatopulmanary syndrome: morbidity and survival after liver transplantation 显示文摘 | Deberaldini M Arcanjo A Mel E | 2008 | Transplant Proc2008，40，10： | 1 |
| 14 | Self-organization of sulfonated polystyrene ionomers in low-polarity solvents显示文摘 | LEBEDEV V T MEL' NIKOV A B VINOGRADOVA L V | 2010 | Polymer Science Series C2010，52，1： | 1 |
| 15 | Levels of Dependency in Linguistic Description:Concepts and Problems显示文摘 | Mel(c)uk I A | 2003 | Dependency and Valency2003，，1： | 1 |
| 16 | Some eounterexamples associated with the three color problem显示文摘 | Aksionov V A Mel'nikov L S | 1980 | J Combin Theory Serie B1980，28，1： | 1 |
| 17 | The technology and equipment for cast steel shot production显示文摘 | Volkov D A Mel'nikov A P Rassudov V L | 2002 | Litejnoe Proizvodstvo2002，，1： | 1 |
| 18 | Degenerate distribution semigroups and well-sosedness of the Cauchy problem显示文摘 | Mel'nikova I V Anufrieva V A Ushkov V Yu | 1998 | Integral Transform and Special Functions1998，6，： | 1 |
| 19 | Selenium (Se) in foods in northern Mexico,their contribution to the daily Se intake and the relationship of Se plasma levels and glutathione peroxidase activity显示文摘 | Wyatt C J Juana María Meléndez J M Acuna N | 1996 | Nutr Res1996，16，6： | 1 |
| 20 | The influence of ionic liquid's nature on free radical polymerization of vinyl monomers and ionic conductivity of the obtained polymeric materials显示文摘 | Vygodskill Y S Mel'nik O A Lozinskaya E I | 2007 | Polym Adv Technol2007，18，1： | 1 |
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