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| 1 | Stem cell application for osteoarthritis in the knee joint: A minireview显示文摘Knee osteoarthritis is a chronic, indolent disease that will affect an ever increasing number of patients, especially the elderly and the obese. It is characterized by degeneration of the cartilage substance inside the knee which leads to pain, stiffness and tenderness. By some estimations in 2030, only in the United States, this medical condition will burden 67 million people. While conventional treatments like physiotherapy or drugs offer temporary relief of clinical symptoms, restoration of normal cartilage function has been difficult to achieve. Moreover, in severe cases of knee osteoarthritis total knee replacement may be required. Total knee replacements come together with high effort and costs and are not always successful. The aim of this review is to outline the latest advances in stem cell therapy for knee osteoarthritis as well as highlight some of the advantages of stem cell therapy over traditional approaches aimed at restoration of cartilage function in the knee. In addition to the latest advances in the field, challenges associated with stem cell therapy regarding knee cartilage regeneration and chondrogenesis in vitro and in vivo are also outlined and analyzed. Furthermore, based on their critical assessment of the present academic literature the authors of this review share their vision about the future of stem cell applications in the treatment of knee osteoarthritis. | Kristin Uth Dimitar Trifonov | 2014 | World Journal of Stem Cells2014，6，5： | 6 |
| 2 | Dose dependent induction of transforming growth factor beta (TGF-beta) in the lung tissue of fibrosis-prong mice after thoracic irradiation显示文摘 | Rube CE Uthe D Schmid KW | 1999 | Int J Radiol1999，21，9： | 2 |
| 3 | 草原生态系统生态补偿机制研究:中德案例研究比较(英文)显示文摘目前,草地生态系统退化成为全球关注的问题。生态补偿机制(PES)是为了草地生态系统的恢复/保护,采取补贴或支付费用的方式,改变使用者资源利用方式的制度安排。科学、合理的生态补偿制度需要全面地考虑可能出现的风险和挑战:如环境效益的滞后性,不可预见的监督、管理成本和社会经济目标(足额补偿标准、公平)的实现。本文的目标是通过中德两国生态补偿措施的对比(选取中国内蒙古锡林郭勒盟,德国勃兰登堡州为案例区域进行研究),为今后中德两国的生态补偿理论和实践提供依据。研究着重以下四个方面进行分析:中德两国生态补偿的实施框架,目标人群,实施效果评估等。研究结果表明,由于缺乏有效的激励机制,农户作为最基层的执行单位和实施者,其参与的主动性不够,中德两国生态补偿措施实施的成效有待提高。基于研究结果,提出了今后生态补偿项目设计中,中国应侧重于项目实施的监控和管理制度;而德国应在空间目标规划和具体管理措施和方式等方面进行完善。 | Sandra UTHES 李芬 甄霖 曹晓昌 | 2010 | Journal of Resources and Ecology2010，1，4： | 2 |
| 4 | Dose-dependent induction of transforming growth factor beta (TGF-beta) in the lung tissue of fibrosis-prone mice after thoracic irradiation显示文摘 | Rübe CE Uthe D Schmid KW | 2000 | Int J Radiat Oncol Biol Phys2000，47，4： | 1 |
| 5 | Reactivity of various mediator and laccase with kraft pulp and lignin model compound显示文摘 | BOURBONNAISER PAICEMG FREIERM UTH B et ai | 1997 | Appl Environ Microbio1997，63，12： | 1 |
| 6 | Dose dependent induction of transforming growth factor beta(TGF-bera) in the lung tissue of fibrosisprone mice after thoracic irradiation显示文摘 | Rube C E Uthe D Schmid K W | 2000 | Int J Radiat Oncol Biol Phys2000，47，4： | 1 |
| 7 | Induction of apoptosis by chemotherapeutic drugs without generation of reactive oxygen species显示文摘 | Senturker S T-schirret-G uth R Morrow J | 2002 | Arch Biochem Biophys2002，397，2： | 1 |
| 8 | The bronehiolar epithelium as a prominent source of pro-inflammatory eytoklnes after lung irradiation 显示文摘 | Rube C E Uthe D Wilfert F | 2005 | Int J Radiat Oncol 8iol Phys2005，61，5： | 1 |
| 9 | Analysis of porcine differential gene expression following challenge with Salmonella enterica serovar Choleraesuis using suppression subtractive hybridization显示文摘 | Jolita J Uthe T Thomas J | 2006 | Veterinary Microbiology2006，114，12： | 1 |
| 10 | Total intravenous anaesthesia with propofol and remifentanil in paediatric patients:a comparison with a desflurane - nitrous oxide inhalation anaesthesia显示文摘 | Grundmann U Uth M Eichner A | 1998 | Acta Anaesthesiol Scand1998，42，7： | 1 |
| 11 | Trends in majoi industrial accidents in Germany 显示文摘 | UTH H J | 1999 | Journal of Loss Prevention in the Process Industries1999，12，1： | 1 |
| 12 | Does vitamin-D intake during resistance training improve the skeletal muscle hypertrophic and strength response in young and elderly men?-a randomized controlled trial显示文摘 | Agergaard J Trostrup J Uth J | 2015 | Nutr Metab(lond)2015，12，： | 1 |
| 13 | The bronchiolar epitheli- um as a prominent source of pro-inflammatory cytokines after lung irradiation显示文摘 | Rube CE Uthe D Wilfert F | 2005 | Int J Radiat Oncol Biol Phys2005，61，5： | 1 |
| 14 | Dose dependent induction of transforming growth factor beta(TGF-beta)in the lung tissue of fibrosis-prone mice after thoracic irradiation显示文摘 | Rube C E Uthe D Sehmid K W | 2000 | Int J Radiat Oncol Biol Phys2000，47，4： | 1 |
| 15 | Dose-dependent induction of transforming growth factor beta(TGF-beta) in the lung tissue of fibrosisprone mice after thoracic irradiation显示文摘 | Rube CE Uthe D Schmid KW | 2000 | Int J Radiat Oncol Biol Phys2000，47，2： | 1 |
| 16 | Variables Affecting Weld Quality in Ultrasonic Aluminum Wire Bonding显示文摘 | UTHE P M | 1969 | Solid State Tech1969，8，8： | 1 |
| 17 | The bronchiolar epithelium as a prominent source of pro-inflammatory eytokines after lung irradiation Int显示文摘 | Rube CE Uthe D Wilfert F | 2005 | J Radiation Oneology Biol Phys2005，61，： | 1 |
| 18 | Targeting translation initiation bypasses signaling crosstalk mechanisms that maintain high MYC levels in colorectal cancer显示文摘 | Wiegering A Uthe FW Jamieson T | 2015 | Cancer Discov2015，5，7： | 1 |
| 19 | Dose dependent induction of transforming growth factor beta (TGF-beta) in the lung tissue of fibrosis-prone mice after thoracic irradiation显示文摘 | Rube CE Uthe D Schrnid KW | 2000 | Int J Radiat Oncol Biol Phys2000，47，7： | 1 |
| 20 | The bronchiolar epithelium as a promintent source of pro-inflammatory cytokines after lung irradia-tion显示文摘 | Rube CE Uthe D Wilfe F | 2005 | Int J Radiata Oncol Biolphys2005，61，5： | 1 |
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