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| 1 | NG2 Cell Response in the CNP-EGFP Mouse After Contusive Spinal Cord Injury显示文摘成年动物中枢神经系统中的NG2细胞具有异质性。脊髓损伤(SCI)后,具有少突胶质前体细胞(OPCs)功能的NG2细胞亚型如何产生反应性变化及对其正常的发育过程有何影响目前还不清楚。本文采用少突胶质细胞系细胞表达EGFP的CNP-EGFP小鼠,研究正常和SCI后的NG2细胞的特征。在正常小鼠的白质中,对EGFP+NG2+双极细胞和EGFPnegNG2+多极细胞进行鉴别。SCI后,白质损伤边缘区中的EGFP+NG2+细胞3 d增殖达高峰,损伤中心区的EGFPnegNG2+细胞增殖在损伤后7 d达高峰。损伤后EGFP+NG2+细胞的Olig2、Sox10、Sox17等转录因子、基本的膜电生理参数以及钾电流表型均与发育过程增殖的OPCs一致。EGFPnegNG2+细胞不表达少突胶质发生中的转录因子。EGFP+CC1+少突胶质细胞6周时包含在EGFP+NG2+细胞增殖峰时表达BrdU的细胞。EGFPnegCC1+少突胶质细胞未被观察到。神经胶质生长因子2和成纤维细胞生长因子2处理促进少突胶质发生,提高EGFPnegNG2+细胞数量。因此,通过EGFP和转录因子表达,时空增殖类型及对生长因子的反应,两种类型的NG2+细胞对SCI刺激发生反应。SCI后EGFP+NG2+细胞经受细胞和生理变化特征,与在早期出生后的少突胶质发生过程中NG2+细胞中的变化类似。 | JUDITH M LYTLE RAMESH CHITTAJALLU JEAN R WRATHALL VITTORIO GALLO | 2009 | 神经损伤与功能重建2009，4，1： | 7 |
| 2 | Optimized Formulation of Magnetic Chitosan Microspheres Containing the Anticancer Agent显示文摘 | Hassan F F Parish R C Gallo J M | 1992 | Oxantrazole Pharm Res1992，9，3： | 2 |
| 3 | Chemotherapy-induced neutropenia: a useful predictor of treatment efficacy显示文摘 | Di Maio M Gridelli C Gallo C | 2006 | Nat Clin Pract Oncol2006，3，3： | 1 |
| 4 | An input-output clustering approach to the synthesis of ANFIS networks显示文摘 | PANELLA M GALLO A S | 2005 | IEEE Transactions on Fuzzy Systems2005，13，1： | 1 |
| 5 | Stress field translation in the healthy human temporomandibular joint 显示文摘 | Gallo L M Nickel J C Iwasaki L R | 2000 | J Dent Res2000，79，10： | 1 |
| 6 | 3D reconstruction of small sized objects from a sequence of multi-focused images显示文摘 | Gallo A Muzzupappa M Bruno F | 2014 | Journal of Cultural Heritage2014，15，2： | 1 |
| 7 | The family business and its social re- sponsibilities显示文摘 | GALLO M A | 2004 | Family Business Review2004，，6： | 1 |
| 8 | Identification of critical residues of the MyD88 death domain involved in the recruitment of downstream kinases 显示文摘 | Loiarro M Gallo G Desantis R | 2009 | J Biol Chem2009，284，28： | 1 |
| 9 | Intestinal mi- crobiota and its flinctions 显示文摘 | Montaho M OnofrioF D Gallo A | 2009 | Digestive and Live Dis- ease Supplements2009，3，2： | 1 |
| 10 | Ultrasono- graphic bone characteristics during normal pregnancy: longitudinal and cross-sectional evaluation显示文摘 | Gamhacciani M Spinetti A Gallo R | 1995 | Am J Obstet Gynecol1995，173，31： | 1 |
| 11 | Identif- ying Influential Spreaders in Complex Networks 显示文摘 | Kitsak M Gallos L K Havlin S | 2010 | Na- ture Physics2010，6，11： | 1 |
| 12 | Chemotherapy-induced neutropenia and treatment efficacy in advanced non-small-cell lung cancer:a pooled analysis of three randomized trials显示文摘 | Di Maio M Gridelli C Gallo C | 2005 | Lancet Oncol2005，6，9： | 1 |
| 13 | Analysis of albumin microsphere preparation显示文摘 | Gallo J M Hung C T Perrier D G | 1984 | Int J Pharm1984，22，： | 1 |
| 14 | Targeting anticancer drugs to the brain: physiological pharmacokinetic model of oxantrazole following intraarterial administration to rat glioma-2(RG-2) bearing rats显示文摘 | Gallo J M Varkonyi P Hassan E E | 1993 | J Pharmacokinet Biopharm1993，21，： | 1 |
| 15 | Continuing follow-up of malignant hypertension 显示文摘 | SCARPELLI P T GALLO M DE CESARIS F | 2002 | J Nephrol2002，15，4： | 1 |
| 16 | Thyroid safety in patients treated with liraglu- tide显示文摘 | Gallo M | 2013 | J Endocrinol Invest2013，36，2： | 1 |
| 17 | Receptor-mediator magnetic carriers:basis for tar-geting显示文摘 | HASSAN E E | 1988 | Pharm Res1988，5，： | 1 |
| 18 | Media optimization for maximum biomass production in cell cultures of pacific yew显示文摘 | Ketchum R E B Gibson D M Gallo L G | 1995 | Plant Cell Tissue and Organ Culture1995，42，2： | 1 |
| 19 | Pressurized liquid extraction for the determination of polyphenols in apple显示文摘 | ALONSO-SALCES R M KORTA E BARRANCO A BERRUETA L A GALLO B VICENTE F | 2001 | Journal of Chromatography A2001，933，1： | 1 |
| 20 | A recombinant single-chain immunotoxin com- posed of anti-Tac variable regions and a truncated diphtheria toxin 显示文摘 | CHAUDHARY V K GALLO M G FITZGERALD D J | 1990 | Proc Natl Acad Sci ( USA )1990，87，23： | 1 |
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