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1529篇 您的检索式:作者名="GILS J"
    题名 作者 年代 出处 被引量
1Schistosoma mansoni proteins attenuate gastrointestinal motility disturbances during experimental colitis in mice显示文摘AIM:To investigate the therapeutic effect of Schistosoma mansoni(S.mansoni) soluble worm proteins on gastrointestinal motility disturbances during experimental colitis in mice. METHODS:Colitis was induced by intrarectal injection of trinitrobenzene sulphate(TNBS) and 6 h later,mice were treated ip with S.mansoni proteins.Experiments were performed 5 d after TNBS injection.Inflammationwas quantified using validated inflammation parameters. Gastric emptying and geometric center were measured to assess in vivo gastrointestinal motility.Peristaltic activity of distal colonic segments was studied in vitro using a modified Trendelenburg set-up.Cytokine profiles of T-lymphocytes isolated from the colon were determined by real time reverse transcriptase-polymerase chain reaction. RESULTS:Intracolonic injection of TNBS caused severe colitis.Treatment with S.mansoni proteins significantly ameliorated colonic inflammation after 5 d.TNBS did not affect gastric emptying but significantly decreased the geometric center and impaired colonic peristaltic activity 5 d after the induction of colitis.Treatment with S.mansoni proteins ameliorated these in vivo and in vitro motility disturbances.In addition,TNBS injection caused a downregulation of effector T cell cytokines after 5 d,whereas a S.mansoni protein effect was no longer observed at this time point. CONCLUSION:Treatment with S.mansoni proteins attenuated intestinal inflammation and ameliorated motility disturbances during murine experimental colitis.Nathalie E Ruyssers Benedicte Y De Winter Joris G De Man Natacha D Ruyssers Ann J Van Gils Alex Loukas Mark S Pearson Joel V Weinstock Paul A Pelckmans Tom G Moreels 2010World Journal of Gastroenterology2010,16,6:11
2AMP-activated kinase in human spermatozoa: identification, intracellular localization, and key function in the reRulation of sperm motility显示文摘Violeta Calle-Guisado Ana Hurtado de Llera David Martin-Hidalgo Jose Mijares Maria C Gil Ignacio S Alvarez Maria J Bragado Luis J Garcia-Marin 2017Asian Journal of Andrology2017,19,6:5
3Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis显示文摘Rayner Katey J Sheedy Frederick J Esau Christine C Hussain Farah N Temel Ryan E Parathath Saj van Gils Janine M Rayner Alistair J Chang Aaron N Suarez Yajaira Fernandez-Hernando Carlos Fisher Edward A Moore Kathryn J 2011Journal of Clinical Investigation2011,,7:2
4Fluorescence studies of poly(p-phenyleneethynylene)s: The effect of antheancene substitution显示文摘Swager T M Gil C J Wrighton M S 1995J Phys Chem 991995,,:2
5Assessment of metal contamination in donana national park (spain) using crayfish (proeamburus elarkia) 显示文摘Sanchez Lopez F J Gil Garcia M D Martinez Vidal J 2004Environmental Monitoring and Assessment2004,,93:1
6Resistance to Corrosion of galvanized steel covered with an epoxy-poly-amideprimer coating 显示文摘Gonzalez S Gil M A Hernandez J O 2001ProgressinOrganicCoatings2001,41,:1
7Formation of α-Widmanst(a)tten structure:effects of grain size and cooling rate on the Widmanst(a)tten morphologies and on the mechanical properties in Ti6Al4V alloy显示文摘GIL F J GINEBRA M P 2001Journal of Alloys and Compounds2001,329,:1
8Effect of the addition of palladium on grain growth kinetics of pure titanium显示文摘Gil F J Picas J A Manero J M 1997J Alloys Compd1997,260,:1
9(1995) Linear time Euclidean distance transform algorithms 显示文摘Breu H Gil J Kirkpatrick D 1995IEEE Transactions on Pattern Analysis and Machine Intelli- gence1995,17,5:1
10Twent - four hour esophageal pH monitoring in gastroesophgeal reflux显示文摘Boix - Ochoa J Lafuente JM Gil - Vernet JM 1980J Pediatr Surg1980,15,:1
11Introducing of apoptosis by the dsRNA dependent protein kinase (PKR): mechanism of action 显示文摘Gil J Esteban M 2000Apoptosis2000,5,2:1
12Linear unequal error protection codes from shorter codes显示文摘Wil J Gils V 1984IEEE Transactions on Information Theory1984,30,3:1
13A study of the abrasive resistance of metal alloys with applications in dental prosthetic fixators显示文摘GIL F J FERNNDEZ E MANNERO J M 1995Biomedical Materials Engineering1995,5,3:1
14Isolation and characterization of abscisic acid-deficient Arabidopsis mutants at two new loci显示文摘Leon-Kloosterziel K M Gil M A Ruijs G J 1996Plant J1996,10,:1
15Effects of flavonoids on naja and human recombinant synovial phospholipases A2 and inflammatory responses in mice 显示文摘Gil B Sanz M J Terencio M C 1994Life Sci1994,54,:1
16Outcome of treatment of Epstein-Barr virus-related post-transplant lymphoproliferative disorder in hematopoietic stem cell recipients: a comprehensive review of reported cases显示文摘Styczynski J Einsele H Gil L 2009Transpl Infect Dis2009,11,5:1
17Response of human corneal fibroblasts on silk film surface patterns显示文摘Gil ES Park SH Marchant J 2010Macromolecular Bioscience2010,10,:1
18Functional as-sessment of perforin C2 domain mutations illustrates the critical role for calcium-dependent lipid binding in perforin cytotoxic func- tion显示文摘Urrea Moreno R Gil J Rodriguez-Sainz C 2009Blood2009,113,2:1
19The dual PI3K/ mTOR inhibitor PI-103 promotes immunosuppression, in vivo tumor growth and increases survival of so rafenib- treated melanoma cells 显示文摘Lopez-Fauqued M Gil R Grueso J 2010Int J Cancer2010,126,7:1
20Nonoperative treatment of Achil es tendon rupture:196 consecutive patients with a 7% re-rupture rate显示文摘Ingvar J T?gil M Eneroth M 0,,04:1
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