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| 1 | Primary hepatic carcinoid:A case report and literature review显示文摘Carcinoids are tumors derived from neuroendocrine cells and often produce functional peptide hormones.Approximately 54.5% arise in the gastrointestinal tract and frequently metastasize to the liver.Primary hepatic carcinoid tumors(PHCT) are extremely rare;only 95 cases have been reported.A 65-year-old man came to our attention due to occasional ultrasound findings in absence of clinical manifestations.His previous medical history,since 2003,included an echotomography of the dishomogeneous parenchymal area but no focal lesions.A computed tomography scan performed in 2005 showed an enhanced pseudonodular-like lesion of about 2 cm.Cholangio-magnetic resonance imaging identified the lesion as a possible cholangiocarcinoma.No positive findings were obtained with positron emission tomography.Histology suggested a secondary localization in the liver caused by a low-grade malignant neuroendocrine tumor.Immunohistochemistry was positive for anti chromogranin antibodies,Ki67 antibodies and synaptophysin.Octreoscan scintigraphy indicated intense activity in the lesion.Endoscopic investigations were performed to exclude the presence of extrahepatic neoplasms.Diagnosis of PHCT was established.The patient underwent left hepatectomy,followed by hormone therapy with sandostatine LAR.Two months after surgery he had a lymph nodal relapse along the celiac trunk and caudate lobe,which was histologically confirmed.The postoperative clinical course was uneventful,with a negative follow-up for hematochemical,clinical and radiological investigations at 18 mo post-surgery.Diagnosis of PHCT is based principally on the histopathological confi rmation of a carcinoid tumor and the exclusion of a non-hepatic primary tumor.Surgical resection is the recommended primary treatment for PHCT.Recurrence rate and survival rate in patients treated with resection were 18% and 74%,respectively. | Luigi Maria Fenoglio Sara Severini Domenico Ferrigno Giovanni Gollè Cristina Serraino Christian Bracco Elisabetta Castagna Chiara Brignone Fulvio Pomero Elena Migliore Ezio David Mauro Salizzoni | 2009 | World Journal of Gastroenterology2009，15，19： | 14 |
| 2 | 挑战四维空间显示文摘拓扑学是十九世纪形成的一门属于几何学范畴的数学分支,它和以往人们所研究的几何有所不同。通常的平面几何或立体几何研究的对象是点、线、面之间的位置关系以及它们的度量性质,如角度、长度、面积、体积等。而拓扑学研究的是经过一系列扭曲、拉伸、压缩等操作仍然不变的性质。在拓扑学中有一些极具特色的描述性模型,如Mobius(莫比鸟斯)带,Kleins(克莱因)瓶等,它们都是拓扑学的典型研究对象。 | 李淼 John Gollings | 2008 | 建筑知识2008，，2： | 3 |
| 3 | Eukaryotic cytosine methyltransferases显示文摘 | Goll MG Bestor TH | 2005 | Annu Rev Biochem2005，74，： | 1 |
| 4 | Reduced expression of microenviron- mental Thl cytokines accompanies adenmnas-carcinomas sequence of colorectum 显示文摘 | Cui G Goll R Olsen T | 2007 | Cancer lmmunol lmmunother2007，56，7： | 1 |
| 5 | Immunogenicity of two accelerated hepatitis B vaccination protocols in liver transplant candidates显示文摘 | Engler SH Sauer PW Golling M | 2001 | Eur J Gastroenterol Hepatol2001，13，4： | 1 |
| 6 | Optimal portfolios for logarithmic utility显示文摘 | Thomas Goll Jan Kallsen | 2000 | Stochastic Processes and Their Applications2000，89，： | 1 |
| 7 | The Calpain System显示文摘 | Goll DE Thompson VF Li H | 2003 | Physiol Rev2003，83，3： | 1 |
| 8 | Magnetic and microstructural properties of nanocrystalline exchang coupled PrFeB permanent magnets显示文摘 | Goll D Seeger M Kronmuller H | 1998 | J Magn Mater1998，18，： | 1 |
| 9 | The calpain system显示文摘 | Goll DE Thompson VF Li HQ | 2003 | Physiological Reviews2003，83，3： | 1 |
| 10 | Dynamic changes of interleukin-8 networkalong the colorectal adenoma-carcinoma sequence 显示文摘 | Cui G Yuan A Goll R | 2009 | CancerImmunol Immunother2009，58，11： | 1 |
| 11 | Design study of a miniaturized displacement transducer (MDT) for an active middle ear implant system 显示文摘 | Kaltenbacher D Schachtele J Goll E | 2014 | Biomed Microdevices2014，16，6： | 1 |
| 12 | Tissue levels of tumor necrosis factor-alpha correlates with grade of inflammation in untreated ulcerative colitis显示文摘 | Trine Olsen Rasmus Goll Cui Guang-lin | 2007 | Scandinavian Journal of Gastroenterology2007，42，11： | 1 |
| 13 | Mucosal cytokine gene expression profiles as biomarkers of response to infliximab in ulcerative colitis显示文摘 | Renathe Rismo Trine Olsen Guanglin Cui Ingrid Christiansen Jon Florholmen Rasmus Goll | 2012 | Scandinavian Journal of Gastroenterology2012，，5： | 1 |
| 14 | Top Management Team Composition Corporate Ideology and Firm Performance显示文摘 | | 2001 | Management International Review2001，41，2： | 1 |
| 15 | Is calpain activity regulated by membranes and autolysis or by calcium and calpastatin显示文摘 | Goll D E | 1992 | Bioessays1992，14，： | 1 |
| 16 | The relationship between top management demographic characteristics, rational decision making, environmental munificence, and firm performance 显示文摘 | GOLL I RASHEED A A | 2005 | Organizational Studies2005，，26： | 1 |
| 17 | Magnetic and microstructural properties of nanocrystalline exchange coupled PrFeB permanent magnets显示文摘 | Goll D Seeger M Kronmuller H | 1998 | J Magn Magn Mater1998，185，： | 1 |
| 18 | The calpain system 显示文摘 | Goll DE Thompson VF Li H | 2003 | Physiol Rev2003，83，3： | 1 |
| 19 | The calpain system显示文摘 | Goll D E Thompson VF Li H | 2003 | Physiol Rev2003，83，3： | 1 |
| 20 | Meta- bolic reconstruction for metagenomic data and its ap- plication to the human microbiome 显示文摘 | ABUBUCKER S SEGATA N GOLL J | 2012 | PLoS Compu- tational Biology2012，8，10： | 1 |
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