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118篇 您的检索式:作者名="GRIFFIN P W"
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1Operative complications and economic outcomes of cholecystectomy for acute cholecystitis显示文摘BACKGROUND Recent management of acute cholecystitis favors same admission(SA)or emergent cholecystectomy based on overall shorter hospital stay and therefore cost savings.We adopted the practice of SA cholecystectomy for the treatment of acute cholecystitis at our tertiary care center and wanted to evaluate the economic benefit of this practice.We hypothesized that the existence of complications,particularly among patients with a higher degree of disease severity,during SA cholecystectomy could negate the cost savings.AIM To compare complication rates and hospital costs between SA vs delayed cholecystectomy among patients admitted emergently for acute cholecystitis.METHODS Under an IRB-approved protocol,complications and charges for were obtained for SA,later after conservative management(Delayed),or elective cholecystectomies over an 8.5-year period.Patients were identified using the acute care surgery registry and billing database.Data was retrieved via EMR,operative logs,and Revenue Cycle Operations.The severity of acute cholecystitis was graded according to the Tokyo Guidelines.TG18 categorizes acute cholecystitis by Grades 1,2,and 3 representing mild,moderate,and severe,respectively.Comparisons were analyzed withχ2,Fisher’s exact test,ANOVA,ttests,and logistic regression;significance was set at P<0.05.RESULTS Four hundred eighty-six(87.7%)underwent a SA while 68 patients(12.3%)received Delayed cholecystectomy.Complication rates were increased after SA compared to Delayed cholecystectomy(18.5%vs 4.4%,P=0.004).The complication rates of patients undergoing delayed cholecystectomy was similar to the rate for elective cholecystectomy(7.4%,P=0.35).Mortality rates were 0.6%vs 0%for SA vs Delayed.Patients with moderate disease(Tokyo 2)suffered more complications among SA while none who were delayed experienced a complication(16.1%vs 0.0%,P<0.001).Total hospital charges for SA cholecystectomy were increased compared to a Delayed approach($44500±$59000 vs$35300±$16700,P=0.019).The relative risk of developing a complication was 4.2x[95%confidence interval(CI):1.4-12.9]in the SA vs Delayed groups.Among eight patients(95%CI:5.0-12.3)with acute cholecystitis undergoing SA cholecystectomy,one patient will suffer a complication.CONCLUSION Patients with Tokyo Grade 2 acute cholecystitis had more complications and increased hospital charges when undergoing SA cholecystectomy.This data supports a selective approach to SA cholecystectomy for acute cholecystitis.Christopher P Rice Krishnamurthy B Vaishnavi Celia Chao Daniel Jupiter August B Schaeffer Whitney R Jenson Lance W Griffin William J Mileski 2019World Journal of Gastroenterology2019,25,48:8
2Non-chondritic distribution of the highly siderophile elements in mantle sulfides显示文摘Alard O Griffin W L Lorand J P 2000Nature2000,,407:1
3Widespread Archean basement beneath the Yangtze eraton 显示文摘ZHENG J P GRIFFIN W L O' REILLY S Y 2006Geology2006,7,:1
4Comparative Life- cycleAir Emissions of Coal,Domestic Natural Gas,LNG,and SNG forElectricity Generation 显示文摘Jaramillo P Griffin W M Matthews H S 2007Environmental Science & Technology2007,41,17:1
5Human nutrition, the gut microbiome and the immune system显示文摘KAU A L AHEM P P GRIFFIN N W 2011Nature2011,474,7351:1
6Implications of near-term coal power plant retirement for SO2 and NO: and life cycle GHG emissions显示文摘Venkatesh A Jaramillo P Griffin W M 2012Environ Sci Techn2012,46,18:1
7Trace elements in sulfide inclusions from Yakutian diamonds显示文摘Bulanova G P Griffin W L Ryan C G 1996Contributions to Mineralogy and Petrology1996,124,2:1
8Decoupling of U- Pb and Lu- Hf isotopes and trace elements in zircon from the UHP North Qaidam orogen, NE Tibet (China): Tracing the deep subduction of continental blocks显示文摘Xiong Q Zheng J P Griffin W L 2012Lithos2012,155,:1
9Non-chondritie distribution of the highly siderophile elements in mantle sulphides显示文摘Alard O Griffin W L Lorand J P 2000Nature2000,407,:1
10Pressure and Temperature Effects in Bituminous Coal Pyrolysis:Experimental Observations and a Transient lumped-parameter Model显示文摘Griffin T P Howard J B Peters W A 1994Fuel1994,73,4:1
11Epidermal nerve fiber density: normative reference range and diagnostic efficiency 显示文摘McArthur J C Stocks E A Hauer P Comb- lath D R Griffin J W 1998Arch Neurol1998,55,:1
12Non-chondritic distribution of the highly siderophile elements in mantle sulphides显示文摘Alard O Griffin W L Lorand J P 2000Nature2000,407,6806:1
13Epidermal innerva- tion: changes with aging, topographic location, and in sensory neuropathy显示文摘Lauria G Holland N Hauer P Comblath D R Griffin J W McArthur J C 1999J Neurol Sci1999,164,:1
14Non-chondritic distribution of the highly siderophile elements in mantle sulphides显示文摘ALARD O GRIFFIN W L LORAND J P 2000Nature2000,407,:1
15Vibrio infections on the Gulf Coast : results of first year of regional surveillance显示文摘Levine W C Griffin P M the Gulf Coast Vibrio Working Group 1993J Infect Dis1993,167,:1
16An experimental and modeling study of heating rate and particle size effects in bituminous coal pyrolysis显示文摘Griffin T P Howard J B Peters W A 1993Energy & fu- els1993,7,2:1
17Geochemistry and geochronology of Carboniferous volcanic rocks in the eastern Junggar terrane,NW Chinz Implication for a tectonic transition显示文摘Su Y P Zheng J P Griffin W L 2012Gondwana Research2012,22,:1
18Mineral chemistry and zircon geochronology of xenocrysts and altered mantle and crustal xenoliths from the Aries micaceous kimberlite:constraints on the composition and age of the central Kimberley Craton,Western Australia显示文摘DOWNES P J GRIFFIN B J GRIFFIN W L 2007Lithos2007,93,12:1
19Widespread Archeanbasement beneath the Yangtze craton显示文摘Zheng J P Griffin W L O′Reilly S Y 2006Geology2006,34,6:1
20Granulite xenoliths and their zircons, Tuoynn, NW China: Insights into southwestern Tianshan lower crust显示文摘Zheng J P Griffin W L O'Reilly S Y Precambrian Research0,145,34:1
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