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| 1 | Operative complications and economic outcomes of cholecystectomy for acute cholecystitis显示文摘BACKGROUND Recent management of acute cholecystitis favors same admission(SA)or emergent cholecystectomy based on overall shorter hospital stay and therefore cost savings.We adopted the practice of SA cholecystectomy for the treatment of acute cholecystitis at our tertiary care center and wanted to evaluate the economic benefit of this practice.We hypothesized that the existence of complications,particularly among patients with a higher degree of disease severity,during SA cholecystectomy could negate the cost savings.AIM To compare complication rates and hospital costs between SA vs delayed cholecystectomy among patients admitted emergently for acute cholecystitis.METHODS Under an IRB-approved protocol,complications and charges for were obtained for SA,later after conservative management(Delayed),or elective cholecystectomies over an 8.5-year period.Patients were identified using the acute care surgery registry and billing database.Data was retrieved via EMR,operative logs,and Revenue Cycle Operations.The severity of acute cholecystitis was graded according to the Tokyo Guidelines.TG18 categorizes acute cholecystitis by Grades 1,2,and 3 representing mild,moderate,and severe,respectively.Comparisons were analyzed withχ2,Fisher’s exact test,ANOVA,ttests,and logistic regression;significance was set at P<0.05.RESULTS Four hundred eighty-six(87.7%)underwent a SA while 68 patients(12.3%)received Delayed cholecystectomy.Complication rates were increased after SA compared to Delayed cholecystectomy(18.5%vs 4.4%,P=0.004).The complication rates of patients undergoing delayed cholecystectomy was similar to the rate for elective cholecystectomy(7.4%,P=0.35).Mortality rates were 0.6%vs 0%for SA vs Delayed.Patients with moderate disease(Tokyo 2)suffered more complications among SA while none who were delayed experienced a complication(16.1%vs 0.0%,P<0.001).Total hospital charges for SA cholecystectomy were increased compared to a Delayed approach($44500±$59000 vs$35300±$16700,P=0.019).The relative risk of developing a complication was 4.2x[95%confidence interval(CI):1.4-12.9]in the SA vs Delayed groups.Among eight patients(95%CI:5.0-12.3)with acute cholecystitis undergoing SA cholecystectomy,one patient will suffer a complication.CONCLUSION Patients with Tokyo Grade 2 acute cholecystitis had more complications and increased hospital charges when undergoing SA cholecystectomy.This data supports a selective approach to SA cholecystectomy for acute cholecystitis. | Christopher P Rice Krishnamurthy B Vaishnavi Celia Chao Daniel Jupiter August B Schaeffer Whitney R Jenson Lance W Griffin William J Mileski | 2019 | World Journal of Gastroenterology2019,25,48: | 8 |
| 2 | Non-chondritic distribution of the highly siderophile elements in mantle sulfides显示文摘 | Alard O Griffin W L Lorand J P | 2000 | Nature2000,,407: | 1 |
| 3 | Widespread Archean basement beneath the Yangtze eraton 显示文摘 | ZHENG J P GRIFFIN W L O' REILLY S Y | 2006 | Geology2006,7,: | 1 |
| 4 | Comparative Life- cycleAir Emissions of Coal,Domestic Natural Gas,LNG,and SNG forElectricity Generation 显示文摘 | Jaramillo P Griffin W M Matthews H S | 2007 | Environmental Science & Technology2007,41,17: | 1 |
| 5 | Human nutrition, the gut microbiome and the immune system显示文摘 | KAU A L AHEM P P GRIFFIN N W | 2011 | Nature2011,474,7351: | 1 |
| 6 | Implications of near-term coal power plant retirement for SO2 and NO: and life cycle GHG emissions显示文摘 | Venkatesh A Jaramillo P Griffin W M | 2012 | Environ Sci Techn2012,46,18: | 1 |
| 7 | Trace elements in sulfide inclusions from Yakutian diamonds显示文摘 | Bulanova G P Griffin W L Ryan C G | 1996 | Contributions to Mineralogy and Petrology1996,124,2: | 1 |
| 8 | Decoupling of U- Pb and Lu- Hf isotopes and trace elements in zircon from the UHP North Qaidam orogen, NE Tibet (China): Tracing the deep subduction of continental blocks显示文摘 | Xiong Q Zheng J P Griffin W L | 2012 | Lithos2012,155,: | 1 |
| 9 | Non-chondritie distribution of the highly siderophile elements in mantle sulphides显示文摘 | Alard O Griffin W L Lorand J P | 2000 | Nature2000,407,: | 1 |
| 10 | Pressure and Temperature Effects in Bituminous Coal Pyrolysis:Experimental Observations and a Transient lumped-parameter Model显示文摘 | Griffin T P Howard J B Peters W A | 1994 | Fuel1994,73,4: | 1 |
| 11 | Epidermal nerve fiber density: normative reference range and diagnostic efficiency 显示文摘 | McArthur J C Stocks E A Hauer P Comb- lath D R Griffin J W | 1998 | Arch Neurol1998,55,: | 1 |
| 12 | Non-chondritic distribution of the highly siderophile elements in mantle sulphides显示文摘 | Alard O Griffin W L Lorand J P | 2000 | Nature2000,407,6806: | 1 |
| 13 | Epidermal innerva- tion: changes with aging, topographic location, and in sensory neuropathy显示文摘 | Lauria G Holland N Hauer P Comblath D R Griffin J W McArthur J C | 1999 | J Neurol Sci1999,164,: | 1 |
| 14 | Non-chondritic distribution of the highly siderophile elements in mantle sulphides显示文摘 | ALARD O GRIFFIN W L LORAND J P | 2000 | Nature2000,407,: | 1 |
| 15 | Vibrio infections on the Gulf Coast : results of first year of regional surveillance显示文摘 | Levine W C Griffin P M the Gulf Coast Vibrio Working Group | 1993 | J Infect Dis1993,167,: | 1 |
| 16 | An experimental and modeling study of heating rate and particle size effects in bituminous coal pyrolysis显示文摘 | Griffin T P Howard J B Peters W A | 1993 | Energy & fu- els1993,7,2: | 1 |
| 17 | Geochemistry and geochronology of Carboniferous volcanic rocks in the eastern Junggar terrane,NW Chinz Implication for a tectonic transition显示文摘 | Su Y P Zheng J P Griffin W L | 2012 | Gondwana Research2012,22,: | 1 |
| 18 | Mineral chemistry and zircon geochronology of xenocrysts and altered mantle and crustal xenoliths from the Aries micaceous kimberlite:constraints on the composition and age of the central Kimberley Craton,Western Australia显示文摘 | DOWNES P J GRIFFIN B J GRIFFIN W L | 2007 | Lithos2007,93,12: | 1 |
| 19 | Widespread Archeanbasement beneath the Yangtze craton显示文摘 | Zheng J P Griffin W L O′Reilly S Y | 2006 | Geology2006,34,6: | 1 |
| 20 | Granulite xenoliths and their zircons, Tuoynn, NW China: Insights into southwestern Tianshan lower crust显示文摘 | Zheng J P Griffin W L O'Reilly S Y | | Precambrian Research0,145,34: | 1 |