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| 1 | Differences in atheroma between Caucasian and Asian subjects with anterior stroke:A vessel wall MRI study显示文摘Background and purpose While extracranial carotid artery stenosis is more common among Caucasians and intracranial artery stenosis is more common among Asians,the differences in atherosclerotic plaque characteristics have not yet been extensively examined.We sought to investigate plaque location and characteristics within extracranial carotid and intracranial arteries in symptomatic Caucasians and Chinese using vessel wall MRI.Methods Subjects with recent anterior circulation ischaemic stroke were recruited and imaged at two sites in the USA and China using similar protocols.Both extracranial carotid and intracranial arteries were reviewed to determine plaque location and characteristics.Results The prevalence of extracranial carotid plaque in Caucasians and Chinese was 73.1%and 49.1%,respectively(p=0.055).Prevalence of intracranial plaque was 38.5%and 69.1%in Caucasians and Chinese,respectively(p=0.02).Furthermore,42% of Caucasians and 16%of Chinese had high-risk plaque(HRP)features(intraplaque haemorrhage,luminal surface disruption)in the extracranial carotid artery(p=0.03).The prevalence of HRP features in intracranial arteries was not significantly different between the two cohorts(4%vs 11%;p=0.42).Conclusions Differences in the location and characteristics of cerebrovascular atherosclerosis were identified by vessel wall MRI in US Caucasian and Chinese subjects with recent anterior circulation ischaemic stroke.Extracranial carotid plaques with HRP features were more common in Caucasians.Intracranial plaques were more common in Chinese subjects,but no significant difference between the two cohorts in intracranial HRP prevalence was found.Larger studies using vessel wall imaging to investigate racial differences in cerebrovascular disease may inform underlying mechanisms of HRP development and may ultimately help guide appropriate therapy. | Hiroko Watase Mi Shen Binbin Sui Peiyi Gao Dong Zhang Jie Sun Niranjan Balu Daniel S Hippe Gail P Jarvik Xihai Zhao Rui Li Shuo Chen Chun Yuan Thomas S Hatsukami | 2021 | Stroke & Vascular Neurology2021，6，1： | 4 |
| 2 | Development of an educational cartoon to prevent worm infections in Chinese schoolchildren显示文摘Background:With more than two billion people infected worldwide,soil-transmitted helminths(STH)are the most widespread infections.To date,STH control efforts rely predominantly on recurrent mass drug administration(MDA),which does not prevent reinfection.Additional public health measures including novel health educational tools are required for more sustained integrated control of STH.We describe the development of an educational cartoon video(The Magic Glasses)targeting STH infections in Chinese schoolchildren and its pilot testing in China.We applied an extensive community-based mixed methods approach involving input from the target group of 9–10 year old schoolchildren and key informants,such as teachers,doctors and parents,in order to identify potential STH infection risks in the study area and to formulate key messages for the cartoon.The development of the educational cartoon included three major steps:formative research,production,and pilot testing and revision.Results:We found that most adults and approximately 50%of the schoolchildren were aware of roundworm(Ascaris)infection,but knowledge of transmission,prevention and treatment of STH was poor.Observations in the study area showed that unhygienic food practices,such as eating raw and unwashed fruit or playing in vegetable gardens previously fertilised with human faeces,posed major STH infection risks.Conclusions:It was crucial to assess the intellectual,emotional,social and cultural background of the target population prior to video production in order to integrate the key messages of the cartoon into everyday situations.Overall,our strategy for the development of the cartoon and its incorporation into a health education package proved successful,and we provide a summary of recommendations for the development of future educational videos based on our experiences in China. | Franziska A Bieri Li-Ping Yuan Yue-Sheng Li Yong-Kang He Andrew Bedford Robert S Li Feng-Ying Guo Sheng-Ming Li Gail M Williams Donald P McManus Giovanna Raso Darren J Gray | 2013 | Infectious Diseases of Poverty2013，2，1： | 2 |
| 3 | Composition and quantities of dust produced by AGB-stars and returned to the interstellar medium 显示文摘 | Ferrarotti A S Gail H P | 2006 | Astronomy and Astrophysics2006，447，： | 1 |
| 4 | MBE springs blue-violet laser diodes显示文摘 | GAIL P | 2004 | Euro Ⅲ-Vs Review2004，17，2： | 1 |
| 5 | Autochthonous eukary- otic diversity in hydrothermal sediment and experimental microeol- onizers at the Mid-Atlantic Ridge 显示文摘 | Lopez-Gareia P Philippe H Gail F | 2003 | Proc Natl Acad Sci USA2003，100，2： | 1 |
| 6 | Particulate pollution capture by urban trees:effect of species and windspeed显示文摘 | K Paul Becett P H Freer-Smith Gail Taylor | | 0，，06： | 1 |
| 7 | Investigating the Effect of Carbon Shape on Virus Adsorption 显示文摘 | Traci P Gail M B Marit J | 2000 | Environ Sci Technol2000，34，13： | 1 |
| 8 | Increased risk of hepatocellular carcinoma in male hepatitis B surface antigen carriers with chronic hepatitis who have detectable urinary aflatoxin metabolite M1显示文摘 | Sun Z Lu P Gail MH | 1999 | Hepatology1999，30，2： | 1 |
| 9 | Particulate pollution capture by urban trees:effect of species and windspeed显示文摘 | K Paul Becett P H Freer-Smith Gail Taylor | 2000 | Global Change Biology2000，，6： | 1 |
| 10 | Increased risk of hepatocellular carcinoma in male hepatitis B surface antigen carriers with chronic hepatitis who have detectable urinary aflatoxin metabolite M1显示文摘 | Sun Z Lu P Gail MH | | 0，，： | 1 |
| 11 | Weighing the risks and benefits of tamoxifen treatment for preventing breast cancer显示文摘 | Gail M H Costantino J P Bryant J | 1999 | J Natl Cancer Inst1999，91，21： | 1 |
| 12 | Investigating the Effect of Carbon Shape on Vires Adsorption 显示文摘 | Traci P Gail M B Marit J | 2000 | Environ Sci Techno12000，34，13： | 1 |
| 13 | Sinus tympani : anatomic considerations, computed tomography, and a discussion of the retrofacial approach for removal of disease 显示文摘 | PICKETT B P GAIL W S LAMBERT P R | 1995 | Am J Otol1995，16，6： | 1 |
| 14 | Genomic pro?filing of myeloid sarcoma by array comparative ge?nomic hybridization显示文摘 | DEEB G BAER M R GAILE D P | 2005 | Genes Chromosomes Cancer2005，44，： | 1 |
| 15 | Purification and characterization of urease from Helicobacter pylori显示文摘 | Bruce E Dunn Gail P Campbell Guillermo I | 1990 | The Journal of Biological Chemistry1990，16，265： | 1 |
| 16 | Unsedated ultrathin EGD is well accepted when compared with conventional sedated EGD: a multicenter randomized trial显示文摘 | Ruel T Garcia John P Cello Mindie H Nguyen Stanley J Rogers Alex Rodas Huy N Trinh Neil H Stollman Gail Schlueck Kenneth R McQuaid | 2003 | Gastroenterology2003，，6： | 1 |
| 17 | Investigating the effect of carbon shape on virus adsorption显示文摘 | Traci P Gail M B Marit J | 2000 | Environ Sci Technol2000，34，13： | 1 |
| 18 | Increased risk of hepatocellular carcinoma in male hepatitis B surface antigen carriers with chronic hepatitis who have detectable urinary aflatoxin metabolite M1显示文摘 | Sun Z Lu P Gail MH | 1999 | Hepatology1999，30，2： | 1 |
| 19 | Increased risk of hepatocellularcarcinoma in male hepatitis B surface antigen carriers withchronic hepatitis who have detectable urinary aflatoxin me-tabolite M1显示文摘 | Sun Z Lu P Gail MH | 1999 | Hepatology1999，30，2： | 1 |
| 20 | Effect of high- versus low-dose angiotensin converting enzyme inhibition on cytokine levels in chronic heart failure显示文摘 | Lars Gullestad P?l Aukrust Thor Ueland Terje Espevik Gail Yee Randall Vagelos Stig S. Fr?land Michael Fowler | 1999 | Journal of the American College of Cardiology1999，，7： | 1 |
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