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| 1 | 3D bioactive composite scaffolds for bone tissue engineering显示文摘Bone is the second most commonly transplanted tissue worldwide,with over four million operations using bone grafts or bone substitute materials annually to treat bone defects.However,significant limitations affect current treatment options and clinical demand for bone grafts continues to rise due to conditions such as trauma,cancer,infection and arthritis.Developing bioactive three-dimensional(3D)scaffolds to support bone regeneration has therefore become a key area of focus within bone tissue engineering(BTE).A variety of materials and manufacturing methods including 3D printing have been used to create novel alternatives to traditional bone grafts.However,individual groups of materials including polymers,ceramics and hydrogels have been unable to fully replicate the properties of bone when used alone.Favourable material properties can be combined and bioactivity improved when groups of materials are used together in composite 3D scaffolds.This review will therefore consider the ideal properties of bioactive composite 3D scaffolds and examine recent use of polymers,hydrogels,metals,ceramics and bio-glasses in BTE.Scaffold fabrication methodology,mechanical performance,biocompatibility,bioactivity,and potential clinical translations will be discussed. | Gareth Turnbull Jon Clarke Frederic Picard Philip Riches Luanluan Jia Fengxuan Han Bin Li Wenmiao Shu | 2018 | Bioactive Materials2018，3，3： | 40 |
| 2 | CA19-9 antigen levels can distinguish between benign and malignant pancreaticobiliary disease显示文摘BACKGROUND:CA19-9 is a carbohydrate tumor-associated antigen which is frequently upregulated in pancreatobiliary neoplasia.However,it may also be elevated in patients with jaundice in the absence of a tumor due to biliary obstruction,and in other non-hepato-pancreatico-biliary conditions.This study aimed to evaluate whether CA19-9 levels could accurately differentiate between benign and malignant pancreatobiliary disease.METHODS:All patients referred to a single surgeon for investigation of pancreaticobiliary disease in 2003 in whom a firm diagnosis had been established were included.For malignant disease,a histological diagnosis was required but for benign disease a firm radiological diagnosis was deemed adequate.The patients were divided into 4 categories:pancreatic adenocarcinoma(PCa);cholangiocarcinoma(CCa);chronic pancreatitis(CP)and biliary calculous disease(Calc).Bilirubin and alkaline phosphatase levels corresponding to the point of assessment of CA19-9 were also noted.RESULTS:Final diagnoses were made of pancreatic adenocarcinoma(PCa,n=73),cholangiocarcinoma(CCa,n=19),ampullary carcinoma(Amp,n=7),neuroendocrine carcinoma(Neu,n=4),duodenal carcinoma(Duo,n=3),chronic pancreatitis(CP,n=115),and biliary calculous disease(Calc,n=27).Median CA19-9 levels(U/ml)were:PCa,653;CCa,408;Duo,403;Calc,27;CP,19;Neu,10.5;Amp,8(reference range:0-37).The CA19-9 levels were significantly greater for malignant than for benign disease,could differentiate PCa from CCa/Duo,and were significantly higher in unresectable than in resectable PCa.The sensitivity,specificity,positive predictive value(PPV)and negative predictive value(NPV)for CA19-9 were 84.9%,69.7%,67.7%and 86.1%,respectively.A ROC analysis provided an area under the curve for CA19-9 of 0.871(0.820-0.922),giving an optimal CA19-9 of 70.5 U/ml for differentiating benign from malignant pathology.Using this cut-off,the sensitivity was 82.1%,while specificity,PPV and NPV improved to 85.9%,81.3%and 86.5%,respectively.When standard radiology was included(US/ CT/MRCP)in the decision process,the results improved to 97.2%,88.7%,86.6%,and 97.7%.For benign disease,the CA19-9 correlated directly with the serum bilirubin,but for malignant disease,CA19-9 levels were elevated independent of the bilirubin level.CONCLUSIONS:CA19-9 is useful in the differentiation of pancreatobiliary disease and when using an optimized cut-off and combining with routine radiology,the diagnostic yield is improved significantly,thus stressing the importance of a multi-disciplinary approach to pancreatobiliary disease. | Gareth Morris-Stiff Mary Teli Nicky Jardine Malcolm CA Puntis | 2009 | Hepatobiliary & Pancreatic Diseases International2009，8，6： | 33 |
| 3 | 考虑负荷控制的配电网故障恢复显示文摘用户参与市场程度的逐步提高为配电网的调度运行提供了更多、更灵活的手段。文中将负荷控制引入到配电网故障恢复问题中,建立了考虑可中断负荷参与的配电网故障恢复优化模型。可中断负荷的引入不仅有利于在系统供电容量不足时最大限度地保证重要负荷供电,而且有利于在配电网仍存在大量手动开关的现状下,降低开关操作时间,以保证重要负荷供电的快速恢复。针对该多目标多约束的优化问题,应用改进的非支配排序遗传算法Ⅱ(NSGA-Ⅱ)进行求解。与传统的遗传算法相比,NSGA-Ⅱ无须通过权重系数将多目标转换为单目标,因此所得到的最优解集更能够反映优化问题的本质。算例计算结果验证了所提出的模型和算法的正确性和有效性。 | 黄弦超 张粒子 Gareth TAYLOR | 2010 | 电力系统自动化2010，34，17： | 24 |
| 4 | 基于节点深度编码技术的配电网故障恢复显示文摘应用智能优化算法求解配电网故障恢复问题时,不仅需要在网络结构发生改变时频繁进行网络拓扑分析,而且往往需要在寻优过程中增加辐射校验环节以保证不违背配电网辐射运行约束,导致消耗了大量时间,降低了算法的寻优性能。将节点深度编码(NDE)技术引入多目标优化算法——改进的非支配遗传算法(NSGA-Ⅱ)中,采用NDE技术中的保留初始节点(PAO)和改变初始节点(CAO)操作取代传统算法中的交叉和变异操作,并针对配电网故障恢复问题的特点,提炼了PAO和CAO操作中的选点规则,保证了算法在寻优过程中始终满足配电网辐射运行约束;同时,通过应用NDE技术,可快速得到新的网络拓扑结构,无需重复进行网络拓扑分析,大大减少了算法的寻优时间。算例计算结果表明,基于NDE技术的NSGA-Ⅱ比普通NSGA-Ⅱ具有更好的收敛性、分布性,以及更快的计算速度。 | 黄弦超 Gareth TAYLOR | 2011 | 电力系统自动化2011，35，6： | 22 |
| 5 | 面向同步相量轨迹簇规则的电力系统暂态稳定实时评估显示文摘设计同步相量测量条件下,面向发电机节点电压同步相量复平面轨迹规则的暂稳实时评估算法。利用K均值和模糊C均值组合算法在线识别扰动后若干周波内轨迹簇同调与聚类偏移特征,采用分类与回归树抽取所定义特征量规则,以实时轨迹簇的相对位置组合特征值规则而非轨迹状态(如幅值大小)本身来评估未来暂稳状态。实践表明,算法能在8~20周波内不依赖模型地高精度预估未来4 s系统是否稳定及临界机、受扰程度等重要信息,且不依赖于既定扰动模式,侧重于系统对大扰动的泛化响应模式挖掘,回避了主导失稳模式判别,且避免了针对不同故障的多套规则存储。新英格兰10机39节点系统算例验证了方法的有效性。 | 刘友波 刘俊勇 Gareth Taylor 刘利民 李俊 | 2011 | 中国电机工程学报2011，31，16： | 17 |
| 6 | Role of live microbial feed supplements with reference to anaerobic fungi in ruminant productivity: A review显示文摘To keep the concept of a safe food supply to the consumers, animal feed industries world over are showing an increasing interest in the direct-fed microbials(DFM) for improved animal performance in terms of growth or productivity. This becomes all the more essential in a situation, where a number of the residues of antibiotics and/or other growth stimulants reach in milk and meat with a number of associated potential risks for the consumers. Hence, in the absence of growth stimulants, a positive manipulation of the rumen microbial ecosystem to enhance the feedstuff utilization for improved production efficiency by ruminants has become of much interest to the researchers and entrepreneurs. A few genera of live microbes(i.e., bacteria, fungi and yeasts in different types of formulations from paste to powder) are infrequently used as DFM for the domestic ruminants. These DFM products are live microbial feed supplements containing naturally occurring microbes in the rumen. Among different DFM possibilities, anaerobic rumen fungi(ARF) based additives have been found to improve ruminant productivity consistently during feeding trials. Administration of ARF during the few trials conducted, led to the increased weight gain, milk production, and total tract digestibility of feed components in ruminants. Anaerobic fungi in the rumen display very strong cell-wall degrading cellulolytic and xylanolytic activities through rhizoid development, resulting in the physical disruption of feed structure paving the way for bacterial action. Significant improvements in the fiber digestibility were found to coincide with increases in ARF in the rumen indicating their role. Most of the researches based on DFM have indicated a positive response in nutrient digestion and methane reducing potential during in vivo and/or in vitro supplementation of ARF as DFM. Therefore, DFM especially ARF will gain popularity but it is necessary that all the strains are thoroughly studied for their beneficial properties to have a confirmed ‘generally regarded as safe' status for ruminants. | Anil K Puniya Abdelfattah Z M Salem Sanjay Kumar Sumit S Dagar Gareth W Griffith Monica Puniya Sreenivas R Ravella Nikhil Kumar Tejpal Dhewa Ravinder Kumar | 2015 | Journal of Integrative Agriculture2015，14，3： | 17 |
| 7 | 基于发电机对暂态势能集的电力系统暂态稳定快速评估显示文摘基于传统暂态能量函数方法,以简单3机3节点系统推导出一种基于发电机对暂态势能的系统暂态势能函数表达式。该暂态势能计算函数不需要全系统的网络拓扑参数或故障位置信息,仅需实时采集系统中少量的发电机机端电气状态量,计算方法简单有效。基于该发电机对暂态势能定义了受扰严重机组判别指标集,利用该指标的聚集特性在故障清除后极短时间内辨识系统的主导失稳模式,根据临界机组分群结果采用EEAC法快速计算当前故障模式下的系统暂态稳定裕度。IEEE 3机9节点、新英格兰10机39节点系统、某省级实际电网算例结果验证了该方法的正确性和有效性。 | 苟竞 刘俊勇 Gareth Taylor Christopher Saunders 刘友波 刘洋 | 2015 | 电网技术2015，39，2： | 16 |
| 8 | 汉语听觉词汇加工中声调信息对语义激活的制约作用(英文)显示文摘进行了三个跨通道启动词汇判断实验 ,探讨汉语听觉词汇加工中声调信息对语义激活的制约作用。实验一和二使用具有相同音段信息、但不同声调信息的双音节合成词 (如“条约”和“跳跃”)作为听觉启动词 ,与其中一个词有语义关系的双字词作为视觉探测词。语义启动词与其配对的声调不匹配词在第一音节的声调、第二音节的声调、或两个声调上有所不同。实验三改变语义启动词的第一或第二音节的声调 ,以产生声调不匹配的假词启动项 ;实验三还同时变化了原来的声调与产生的声调之间的相似性。实验结果表明 ,声调不匹配的启动项目是否产生显著的启动效应取决于词汇竞争的环境、声调输入与深层声调表征之间匹配的程度 ,以及不匹配的声调所在的位置。文章从语音输入中的声调信息如何激活词汇表征、声调信息如何存储在心理词典中。 | 周晓林 曲延轩 舒华 Gareth Gaskell William Marslen-Wilson | 2004 | 心理学报2004，36，4： | 13 |
| 9 | 基于多尺度熵的电力能量流复杂性分析显示文摘电力能量流复杂性主要体现于其动态行为的实时性、非线性及不确定性等,网络动力学行为分析是关键.本文在电力系统动力学平衡方程基础上,构建了系统势能与支路势能函数模型;通过提取扰动(或故障)后系统的能量信息,利用多尺度熵对扰动(或故障)后系统能量流演化过程进行了研究.结果表明:1)稳定运行状态下系统复杂度较低,且随着故障持续时间的增加,系统故障后呈现出更高的复杂度;2)不稳定运行状态下,系统在小尺度时间上表现出更强的不确定性,而在大尺度时间上表现出相对更明显的规则性;3)临界稳定运行状态与临界不稳定运行状态下,故障后的系统复杂度在不同时间尺度上呈现出较明显的差异,这对动态过程中临界点的识别有着积极的参考价值.本文研究揭示了电力能量流在物理动态过程中的演化机制,为电力系统动力学行为分析提供了新思路与新方法. | 苟竞 刘俊勇 魏震波 Gareth Taylor 刘友波 | 2014 | 物理学报2014，63，20： | 12 |
| 10 | 食鱼蝙蝠——大足鼠耳蝠初报显示文摘大足鼠耳蝠属蝙蝠科 ,为中国特有种类。食性分析和野外观察证实大足鼠耳蝠为食鱼蝙蝠。室内放养条件下发现大足鼠耳蝠一次进食能连续消耗 5 0~ 1 0 0g麦穗鱼。本研究首次报道北京房山亦有大足鼠耳蝠分布 ,并介绍了其地理分布和保护现状。 | 马杰 JONES Gareth 梁冰 沈钧贤 张树义 | 2003 | 动物学杂志2003，38，3： | 12 |
| 11 | 一种基于发电机对相对能量的电力系统临界机群快速辨识方法显示文摘准确辨识临界失稳机组是暂态稳定分析的关键。该文在推导基于发电机机组对的相对暂态动、势能函数基础上,根据机组对在故障切除时刻和故障切除后两个时步内的相对能量聚集特性,采用两阶段聚类分群算法,对故障切除后极短时间内系统的临界机群进行了辨识。由于相对能量函数的计算不依赖于全系统的网络拓扑参数或故障位置信息,仅需实时采集系统中少量的发电机机端电气状态量,减小了因候选集合漏选重要机组带来的辨识误差,且计算相对简单,缩短了辨识时间。新英格兰10机39节点系统、IEEE 145节点系统算例结果验证了该方法的正确性和有效性。 | 苟竞 刘俊勇 魏震波 Christopher Saunders Gareth Taylor 刘友波 | 2015 | 中国电机工程学报2015，35，24： | 11 |
| 12 | 中国邻近边缘海碳通量研究现状与展望显示文摘集成分析了南海、东黄渤海等中国邻近边缘海(简称中国边缘海)海-气界面CO_2通量及其所表征的CO_2源汇格局,简析海-气CO_2通量的主要控制因素;总结了河-海界面、边缘海与大洋的交换界面及输出真光层的碳通量,进而初步构架了简化的中国边缘海碳收支;并与世界其他陆架边缘海碳的源汇格局和通量作了比对,最后对边缘海碳循环研究进行了展望.从周年尺度上看,中国边缘海是大气CO_2的源,全年向大气的释放量为(9.5±53)Tg C;河流经过河口输送至中国边缘海的总碳量为(59.6±6.4)Tg Ca^(-1);中国境内河口释放CO_2的总量为(0.74±0.02)Tg Ca^(-1);西太平洋每年输入中国边缘海的总碳量为2.5Pg Ca^(-1),可见,西北太平洋输入中国边缘海的碳通量巨大.中国边缘海上层海洋颗粒有机碳输出通量为(240±80)Tg Ca^(-1). | 刘茜 郭香会 尹志强 周宽波 Elliott Gareth ROBERTS 戴民汉 | 2018 | 中国科学:地球科学2018，48，11： | 11 |
| 13 | Why interleukin-10 supplementation does not work in Crohn's disease patients显示文摘Inflammatory bowel diseases (IBD) such as Crohn's disease (CD) or ulcerative colitis are chronic intestina disorders, which are on the increase in 'Westernised' countries. IBD can be caused by both genetic and environmental factors. Interleukin-10 (IL-10) is an immunoregulatory cytokine that has been identified as being involved in several diseases including IBD. Studies have shown that polymorphisms in the promoter region reduce serum levels of IL-10 and this reduction has been associated with some forms of IBD. Mouse models have shown promising results with IL-10 supplementation, as such IL-10 supplementation has been touted as being a possible alternative treatment for CD in humans. Clinical trials have shown that recombinant human IL-10 is safe and well tolerated up to a dose o 8 μg/kg. However, to date, the results of the clinica trials have been disappointing. Although CD activity was reduced as measured by the CD activity index IL-10 supplementation did not result in significantly reduced remission rates or clinical improvements when compared to placebo. This review discusses why IL-10supplementation is not effective in CD patients currently and what can be addressed to potentially make IL-10 supplementation a more viable treatment option in the future. Based on the current research we conclude that IL-10 supplementation is not a one size fits all treatment and if the correct population of patients is chosen then IL-10 supplementation could be of benefit. | Gareth J Marlow Dominique van Gent Lynnette R Ferguson | 2013 | World Journal of Gastroenterology2013，19，25： | 9 |
| 14 | 电力系统连锁故障的多层时序运行演化模型与应用显示文摘为研究电网大停电事故的宏观安全特征,并揭示连锁故障过程中呈现的微观脆弱环节,提出多层时序运行演化模型对连锁故障进行模拟。该模型由运行内层、时序中层及演化外层构成,较传统仿真模型在负荷时序规则、故障传播方式及电网建设等方面均具有更加合理的设置,能够较为真实地反映电网运行、发展与连锁故障的关系。采用IEEE 300节点系统和某省级实际电网作为连锁故障仿真算例,结合电网自组织临界性与负荷损失时序特性,说明所建模型揭示更加了符合实际的连锁故障宏观安全特征;同时,针对仿真结果所揭示的脆弱线路、重要无功支撑节点及故障线路同步性等电网脆弱环节,与已有方法和指标进行对比,验证了所建模型亦可用于揭示电网微观脆弱环节辨识。 | 刁塑 刘友波 刘俊勇 许立雄 Gareth Taylor Maozhen Li | 2015 | 中国电机工程学报2015，35，S1： | 9 |
| 15 | Numerical modelling of riverbed grain size stratigraphic evolution显示文摘For several decades,quantification of riverbed grain size stratigraphic evolution has been based upon the active layer formulation(ALF),which unfortunately involves considerable uncertainty.While it is the sediment exchange across the bed surface that directly affects the riverbed stratigraphy,it has been assumed in the ALF that the sediment fraction at the lower interface of the active layer is a linear function of the sediment fraction in the flow.Here it is proposed that the sediment fraction of the sediment exchange flux is used directly in estimating the sediment fraction at the lower surface of the active layer.Together with the size-specific mass conservation for riverbed sediment,the modified approach is referred to as the surface-based formulation(SBF).When incorporated into a coupled non-capacity modelling framework for fluvial processes,the SBF leads to results that agree as well or better than those using ALF with laboratory and field observations.This is illustrated for typical cases featuring bed aggradation and degradation due to graded bed-load sediment transport.Systematic experiments on graded sediment transport by unsteady flows are warranted for further testing the modified formulation. | Peng HU Zhi-xian CAO Gareth PENDER Huai-han LIU | 2014 | International Journal of Sediment Research2014，29，3： | 9 |
| 16 | Interaction of the Arabidopsis UV-B-Specific Signaling Component UVR8 with Chromatin显示文摘Arabidopsis 紫外抵抗 LOCUS8 (UVR8 ) 是表明调整担心紫外保护的基因的一个范围的表示的部件的 UV-B-specific。这里,我们与染色质调查 UVR8 的相互作用。用对在染色质 immunoprecipitation (薄片) 的 UVR8 特定的抗体有野类型的植物的试金,我们证明本国的 UVR8 在 vivo 绑在染色质。用有表示 GFPUVR8 熔化的植物的 anti-GFP 抗体的类似的实验证明 UVR8 与包含 HY5 基因的染色质的一个相对小的区域联系。UVR8 与包含另外的基因的倡导者区域的染色质交往,然而并非与所有基因,它调整。因为有几基因 loci 的协会当 UV-B 不在时被观察, UV-B 没为和染色质的 UVR8 的相互作用被要求。下拉试金证明有在 vivo 和比赛实验的 histones 的 UVR8 伙伴显示相互作用是优先地与 histone H2B。用认出特定的 histone 修正的抗体的薄片实验显示一些基因的 UV-B-stimulated 抄写可以与 histone 修正被相关。特别地, ELIP1 倡导者显示出跟随 UV-B 暴露的 diacetyl histone H3 (K9/K14 ) 的重要丰富。有染色质的关键 UV-B-specific 管理者 UVR8 的相互作用的这些调查结果增加理解。 | Catherine Cloix Gareth I. Jenkins | 2008 | Molecular Plant2008，1，1： | 9 |
| 17 | 分享教师的科研经验 提高大学生的创新能力-以高压静电纺丝技术为例说明科研反哺教学途径显示文摘分享教师的科研经验,能够有效地实施科研反哺教学、促进大学生自我教育、主动学习、并提高他们的创新能力。以高压静电纺丝技术为例阐述如何通过科研有效地进行反哺教学,提出了五条增强科研反哺教学的途径:课程上多开设探索性实验课,给学生提供更多的分享老师科研经验的机会;多位老师协同教学完成一门课的教学,让学生分享更多老师的科研经验;鼓励学生走进教授团队研究室,感受科研气氛与创新环境;发现学生兴趣,进行因材施教,分享给学生最需要,最能激发灵感的经验;老师应该热爱科研,与时俱进,掌握最先进的科技,积累更多更好的科研经验。 | 余灯广 潘登 王霞 罗傢蛴 Gareth R Williams | 2016 | 上海理工大学学报(社会科学版)2016，38，2： | 8 |
| 18 | 北京房山大足鼠耳蝠食鱼性及回声定位信号显示文摘大足鼠耳蝠 (Myotisricketti)具有食鱼蝙蝠的形态特征 ,但食鱼习性待考。以北京房山种群为对象 ,夜间在洞口悬挂雾网 ,捕获取食返洞大足鼠耳蝠共 18只 ,胃检发现 7例全为鱼类 (宽鳍 ,鲫鱼和洛氏 ) ,10例以鱼类为主 ,仅 1例全为昆虫。室内实验观察到捕鱼行为 2 5 6次 ,成功率 12 5 %。如此 ,该种具食鱼习性的猜测得到证实。回声定位信号属调频型 ,扫频范围从 6 7 4 0kHz到 2 3 6 3kHz ,主频 (38 2 1± 1 18)kHz ,声信号时程 (2 5 8± 0 34)ms。 | 马杰 张礼标 梁冰 沈钧贤 张树义 JONES Gareth | 2003 | Zoological Research2003，24，4： | 8 |
| 19 | Non-capacity transport of non-uniform bed load sediment in alluvial rivers显示文摘Rivers often witness non-uniform bed load sedim ent transport. For a long tim e, non-uniform bed load transport has been assum ed to be at capacity regime determined exclusively by local flow. Yet whether the capacity assumption for non-uniform bed load transport is justified remains poorly understood. Here, the relative time scale of non-uniform bed load transport is evaluated and non-capacity and capacity models are compared for both aggradation and degradation cases with observed data. As characterized by its relative time scale, the adaptation of non-uniform bed load to capacity regime should be fulfilled quickly. However, changes in the flow and sedim ent inputs from upstream or tributaries hinder the adaptation. Also, the adaptation to capacity regime is size dependent, the finer the sediment size the slower the adaptation is, and vice versa. It is shown that the capacity model may entail considerable errors compared to the non-capacity model. For modelling of non-uniform bed load, non-capacity modelling is recommended, in which the temporal and spatial scales required for adaptation are explicitly appreciated. | CAO Zhi-xian HU Peng PENDER Gareth LIU Huai-han | 2016 | Journal of Mountain Science2016，13，3： | 7 |
| 20 | Inflammatory response related scoring systems in assessing the prognosis of patients with pancreatic ductal adenocarcinoma:a systematic review显示文摘BACKGROUND: Various scoring systems based on assessment of the systemic inflammatory response help assessing the prognosis of patients with pancreatic ductal adenocarcinoma.In the present systematic review we evaluated the validity of four pre-intervention scoring systems: Glasgow prognostic score(GPS) and its modified version(mGPS), platelet lymphocyte ratio(PLR), neutrophil lymphocyte ratio(NLR), and prognostic nutrition index(PNI).DATA SOURCES: MOOSE guidelines were followed and EMBASE and MEDLINE databases were searched for all published studies until September 2013 using comprehensive text word and MeSH terms. All identified studies were analyzed, and relevant studies were included in the systematic review.RESULTS: Six studies were identified for GPS/mGPS with3 reporting statistical significance for GPS/mGPS on both univariate analysis(UVA) and multivariate analysis(MVA).Two studies suggested prognostic significance on UVA but not MVA, and in the final study UVA failed to show significance.Eleven studies evaluated the prognostic value of NLR. Six of them reported prognostic significance for NLR on UVA that persisted at MVA in 4 studies, and in the remaining 2 studies NLR was the only significant factor on UVA. In the remaining5 studies, all in patients undergoing resection, there was no significance on UVA. Seven studies evaluated PLR, with only one study demonstrated its prognostic significance on both UVAand MVA, the rest did not show the significance on UVA. Of the two studies identified for PNI, one demonstrated a statistically significant difference in survival on both UVA and MVA, and the other reported no significance for PNI on UVA.CONCLUSIONS: Both GPS/mGPS and NLR may be useful but further better-designed studies are required to confirm their value. PLR might be little useful, and there are at present inadequate data to assess the prognostic value of PNI. At present, no scoring system is reliable enough to be accepted into routine use for the prognosis of patients with pancreatic ductal adenocarcinoma. | Jawad Ahmad Nathan Grimes Shahid Farid Gareth Morris-Stiff | 2014 | Hepatobiliary & Pancreatic Diseases International2014，13，5： | 7 |
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