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| 1 | Age distribution,polyps and rectal cancer in the Egyptian population-based cancer registry显示文摘AIM:To describe the clinical and epidemiologic profiles of the disease and to compare the findings with those generated from the previous hospital-based studies.METHODS:The Gharbiah cancer registry is the only population-based cancer registry in Egypt since 1998.We analyzed the data of all colorectal cancer patients included in the registry for the period of 1999-2007.All medical records of the 1364 patients diagnosed in Gharbiah during the study period were retrieved and the following information abstracted:age,residence,diagnosis date,grade,stage,topology,clinical characteristics,and histology variables.Egyptian census data for 1996 and 2006 were used to provide the general population's statistics on age,sex,residence and other related demographic factors.In addition to age-and sex-specific incidence rate analyses,we analyze the data to explore the incidence distribution by rural-urban differences among the 8 districts of the province.We also compared the incidence rates of Gharbiah to the rates of the Surveillance Epidemiology and End Results(SEER) data of the United States.RESULTS:Over the 9 year-period,1364 colorectal cancer cases were included.The disease incidence under age 40 years was relatively high(1.3/10 5) while the incidence in the age groups 40 and over was very low(12.0/10 5,19.4/10 5 and 21.2/10 5 in the age groups 40-59 years,60-69 years and > 70 years,respectively).The vast majority of tumors(97.2%) had no polyps and 37.2% of the patients presented with primary lesions in the rectum.Colorectal cancer was more common in patients from urban(55%) than rural(45%) areas.Regional differences in colon and rectal cancer incidence in the 8 districts of the study province may reflect different etiologic patterns in this population.The registry data of Egypt shows a slightly higher incidence of colorectal cancer than the United States in subjects under age 40 years.The results also shows significantly lower incidence of colorectal cancer in subjects over age 40 years compared to the same age group in the United States SEER.CONCLUSION:Low rate of polyps,low incidence in older subjects,and high rate of rectal cancer in Egypt.Future studies should explore clinical and molecular disease patterns. | Darlene Veruttipong Amr S Soliman Samuel F Gilbert Taylor S Blachley Ahmed Hablas Mohamed Ramadan Laura S Rozek Ibrahim A Seifeldin | 2012 | World Journal of Gastroenterology2012，18，30： | 12 |
| 2 | 根治性手术与短程放疗后行经肛门内镜显微手术(TEM)保留器官治疗早期直肠癌(TREC):一项随机、开放标签的可行性研究显示文摘背景:基于全直肠系膜切除(total mesorectal excision,TME)的根治性手术可能不是早期直肠癌的最佳一线治疗。选择性TME保留器官的策略可以减少治疗的不良反应,又不会显著影响肿瘤结果。该临床随机研究通过与TME比较,探讨器官保留策略的可行性。方法:TREC是一项在英国21个三级转诊中心进行的随机、开放标签的可行性研究。符合条件的受试者年龄≥18岁,分期为T2期或更早,最大直径不超过30 mm;排除淋巴结受累或转移的患者。患者按计算机随机分配(1:1)接受短程放疗保留器官,8~10周后行经肛门内镜显微手术(transanal endo⁃scopic microsurgery,TEM)或TME术。当TEM标本组织病理学特征提示局部复发风险增加时,患者被考虑计划早期转为TME。一项非随机前瞻性登记收集了认为不适合随机化的患者,因为每例患者都是按临床指征治疗的。主要终点为12、18和24个月的累积随机分组。次要结局为应用欧洲癌症研究与治疗组织(EORTC)QLQ C30和CR29量表对意向治疗人群的安全性、有效性和健康相关生活质量进行了评价。该研究已在ISRCTN注册中心注册,ISRCTN14422743。 | 佟伟华 BACH S P GILBERT A BROCK K | 2021 | 结直肠肛门外科2021，27，3： | 9 |
| 3 | Physico - chemical treatment echniques for wastewater laden with heavy metals 显示文摘 | Kumiawan T A Gilbert Y S Wai H L | 2006 | Chemical Engineering Journal2006，118，12： | 1 |
| 4 | Trickle irrigation water quality and preventive maintenance显示文摘 | Bucks D A Nakayama F S Gilbert R G | 1979 | Agricultural Water Management1979，，2： | 1 |
| 5 | Performance of full cells containing carbonate-based Li FSI electrolytes and silicon-graphite negative electrodes显示文摘 | TRASK S E PUPEK K Z GILBERT J A | 2016 | Journal of the Electrochemical Society2016，163，3： | 1 |
| 6 | A column approximate minimum degree ordering algorithm显示文摘 | Davis T A Gilbert J R Larimore S | 2004 | ACM Transactions on Mathematical Software2004，30，3： | 1 |
| 7 | The degrada- tion of arginine by Clostridium perfringens (BP6K) 显示文摘 | GILBERT C S MILAN A L ALFRED A T | 1952 | Journal of Biological Chemisty1952，198，2： | 1 |
| 8 | Are tropical fungalendophytes hyperdiverse显示文摘 | Arnold A E Maynard Z Gilbert G S | 2000 | Ecological Letters2000，3，4： | 1 |
| 9 | Better understanding of plant and pilot plant operations using on-line mass spectrometry 显示文摘 | DESJARDIN M A DOHERTY S J GILBERT J R | 1995 | Process Control Qual1995，6，： | 1 |
| 10 | Multiple types of skeletal muscle atrophy involve a common program of changes in gene ex- pression显示文摘 | Lecker S H Jagoe R T Gilbert A | 2004 | Faseb J2004，18，1： | 1 |
| 11 | New managerial challenges from supply chain opportunities显示文摘 | Ballou R H Gilbert S M Mukherjee A | 2000 | Industrial Marketing Management2000，29，： | 1 |
| 12 | A constructed microbial consortium for biodegradation of the organophosphorus insecticide parathion显示文摘 | Gilbert E S Walker A W Keasling J D | | 0，，01： | 1 |
| 13 | Photo-initiated polymerization ofacrylarnide in water显示文摘 | Seabrook S A Gilbert R G | 2007 | Polymer2007，48，： | 1 |
| 14 | Near-optimal sparseFourier representations via sampling 显示文摘 | Gilbert A C Guha S Indyk P | 2002 | Proceedingsof the Annual ACM Symposium on Theory of Compu-ting Association for Computing Machinery2002，2，： | 1 |
| 15 | Removal of nonbiodegradable compounds from stabilized leachate using VSEPROmembrane filtration 显示文摘 | Gilbert Y S C Chang Jie Tonni A K | 2007 | Desalination2007，202，13： | 1 |
| 16 | Biodiversitycan support a greener revolution in Africa 显示文摘 | Snapp S S Blackie M J Gilbert R A | 2010 | Proceed- ings of the National Academy of Sciences2010，107，20： | 1 |
| 17 | Repurposing CRISPR as an RNA-guided platform for seguence- specific control of gene expression显示文摘 | Qi L S Larson M H Gilbert L A | 2013 | Cell2013，152，5： | 1 |
| 18 | Compressed Sensing Embedded in an Operational Wireless Sensor Network to Achieve Energy Efficiency in Long-term Monitoring Applications显示文摘 | O’Connor S M Lynch J P Gilbert A C | 2014 | Smart Materials and Structures2014，23，8： | 1 |
| 19 | Photo-initiated polymerization of aerylamide in water显示文摘 | Seabrook S A Gilbert R G | 2007 | Polymer2007，48，： | 1 |
| 20 | Syn- thesis of cholesterol modified cationic lipids for liposo real drug delivery of antisense oligonucleotides显示文摘 | Zimmer A Atmaca-Abdel A S Gilbert M | 1999 | Eur J Pharm Biopharm1999，47，2： | 1 |
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