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11篇 您的检索式:作者名="Gróf"
    题名 作者 年代 出处 被引量
1über Approximation durch Polynome mit Belegungsfunktion显示文摘J. Gróf 1980Acta Mathematica Academiae Scientiarum Hungaricae (-)1980,,1:1
2FASCIN and alpha-actinin can regulate the conformation of actin filaments显示文摘Türmer K Orbán J Gróf P 2015Biochim Biophys Acta2015,1850,9:1
3PhaseⅡstudy of trastuzumab and cisplatin as first-line therapy in patients with HER2-positive advanced gastric or gastroesophageal junction cancer显示文摘Grávalos C Gómez-Martín C Rivera F 2011Clin Transl Oncol2011,13,3:1
4Inverse identification of temperature-dependent thermal conductivity via genetic algorithm with cost function-based rearrangement of genes显示文摘Balázs Czél Gyula Gróf 20122012 (15-16)2012,,15:1
5PhaseⅡstudy of trastuzumab and cisplatin as first-line therapy in patients with HER2-positive advanced gastric or gastroesophageal junction cancer显示文摘Grávalos C Gómez-Martín C Rivera F 2011Clin Transl Oncol2011,13,3:1
6Trypsinogen Stabilization by Mutation Arg117→His: A Unifying Pathomechanism for Hereditary Pancreatitis?显示文摘Miklós Sahin-Tóth László Gráf Miklós Tóth 1999Biochemical and Biophysical Research Communications1999,,2:1
7Characterization of aminoglycoside-modifying enzymes in enterobacteriaceae clinical strains and characterization of the plasmids implicated in their diffusion显示文摘Miró E Grünbaum F Gómez L 2013Microb Drug Resist2013,19,:1
8Expression of rat chymotrypsinogen in yeast: a study on the structural and functional significance of the chymotrypsinogen propeptide显示文摘István Venekei László Gráf William J. Rutter 1996FEBS Letters1996,,2:1
9Mutations in WNT1 cause different forms of bone fragility显示文摘Keupp K Beleggia F Kayserili H Barnes AM Steiner M Semler O Fischer B Yigit G Janda CY Becker J Breer S Altunoglu U Grünhagen J Krawitz P Hecht J Schinke T Makareeva E Lausch E Cankaya T Caparrós-Martín JA Lapunzina P Temtamy S Aglan M Zabel B Eysel P Koe 0,,:1
10Restoration of Motor Function through Delayed Intraspinal Delivery of Human IL-10-Encoding Nucleoside-Modified mRNA after Spinal Cord Injury显示文摘Efficient in vivo delivery of anti-inflammatory proteins to modulate the microenvironment of an injured spinal cord and promote neuroprotection and functional recovery is a great challenge.Nucleoside-modified messenger RNA(mRNA)has become a promising new modality that can be utilized for the safe and efficient delivery of therapeutic proteins.Here,we used lipid nanoparticle(LNP)-encapsulated human interleukin-10(hIL-10)-encoding nucleoside-modified mRNA to induce neuroprotection and functional recovery following rat spinal cord contusion injury.Intralesional administration of hIL-10 mRNA-LNP to rats led to a remarkable reduction of the microglia/macrophage reaction in the injured spinal segment and induced significant functional recovery compared to controls.Furthermore,hIL-10 mRNA treatment induced increased expression in tissue inhibitor of matrix metalloproteinase 1 and ciliary neurotrophic factor levels in the affected spinal segment indicating a time-delayed secondary effect of IL-105 d after injection.Our results suggest that treatment with nucleoside-modified mRNAs encoding neuroprotective factors is an effective strategy for spinal cord injury repair.LászlóGál Tamás Bellák Annamária Marton Zoltán Fekécs Drew Weissman Dénes Török Rachana Biju Csaba Vizler Rebeka Kristóf Mitchell B.Beattie Paulo J.C.Lin Norbert Pardi Antal Nógrádi Krisztián Pajer 2023Research2023,,4:0
11Input database related uncertainty of Biome-BGCMuSo agroenvironmental model outputs显示文摘Gridded model assessments require at least one climatic and one soil database for carrying out the simulations.There are several parallel soil and climate database development projects that provide sufficient,albeit considerably different,observation based input data for crop model based impact studies.The input database related uncertainty of the Biome-BGCMuSo agro-environmental model outputs was investigated using three and four different gridded climatic and soil databases,respectively covering an area of nearly 100.000 km2 with 1104 grid cells.Spatial,temporal,climate and soil database selection related variances were calculated and compared for four model outputs obtained from 30-year-long simulations.The choice of the input database introduced model output variability that was comparable to the variability the year-to-year change of the weather or the spatial heterogeneity of the soil causes.Input database selection could be a decisive factor in carbon sequestration related studies as the soil carbon stock change estimates may either suggest that the simulated ecosystem is a carbon sink or to the contrary a carbon source on the long run.Careful evaluation of the input database quality seems to be an inevitable and highly relevant step towards more realistic plant production and carbon balance simulations.Nándor Fodor LászlóPásztor Brigitta Szabó Annamária Laborczi Klára Pokovai Dóra Hidy Roland Hollós Erzsébet Kristóf Anna Kis Laura Dobor AnikóKern Thomas Grünwald Zoltán Barcza 2021International Journal of Digital Earth2021,14,11:0
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