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52篇 您的检索式：作者名="Grabowski S P"

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	题名	作者	年代	出处	被引量
1	化疗所致恶心呕吐对复发性卵巢癌患者预后的影响:纳入1213例患者数据的meta分析结果显示文摘背景与目的本研究旨在研究化疗所致恶心呕吐(chemotherapy-induced nausea and vomiting,CINV)对化疗药物剂量减少、中止以及患者生存获益的潜在影响。方法本研究基于德国东北妇科肿瘤学会(North-Eastern German Society of Gynecological Oncology,NOGGO)开展的3项Ⅱ/Ⅲ期临床试验中的1213例复发性卵巢癌患者的原始数据,进行了个体病例数据的meta分析。通过Logistic回归和Cox回归分析,对年龄、ECOG评分、化疗周期数、复发次数、并发症以及不同研究等因素进行校正后,评估相应的比值比和风险比(hazard ratio,HR)。结果大多数(58.1%)患者发生了恶心,且近三分之一(31.0%)的患者出现呕吐。CINV的发生与FIGO分期、分级、组织学以及复发次数无关;必须的化疗药物减量和中止化疗与恶心、呕吐的发生亦无相关性(P=0.88,P=0.39;P=0.25,P=0.54)。发生Ⅲ/Ⅳ级恶心呕吐患者的无进展生存期更短(P=0.02,Ⅲ/Ⅳ级恶心的HR=1.58,95%CI:1.14–2.20;P=0.02,Ⅲ/Ⅳ级呕吐的HR=1.67,95%CI:1.15–2.42)。发生Ⅲ/Ⅳ级恶心和呕吐的患者生存期较短(P <0.001,Ⅲ/Ⅳ级恶心的HR=2.35,95%CI:1.64–3.37;P <0.001,Ⅲ/Ⅳ级呕吐的HR=1.67,95%CI:1.15–2.42)。结论 CINV与复发性卵巢癌患者较差的预后显著相关,而与必须的化疗药物减量和中止无相关性。本研究强调CINV防治是早期最佳支持治疗的重要环节。	Hannah Woopen R Richter R Chekerov G Inci S Alavi J P Grabowski J Sehouli 尹如铁(译)	2022	癌症2022，41，6：	2
2	ExDression of nitric oxidesynthase isoforms in bone and bone cell cultures显示文摘	HELFRICH M H EVANS D E GRABOWSKI P S		0，，07：	1
3	The nature of hydrogen bonding involving the siloxane group显示文摘	Grabowsky S Beckmann J Luger P		0，，07：	1
4	Nitric oxide produc- tion in cells derived from the human joint 显示文摘	Grabowski P S Raiston S H Macpherson H	1996	Br J Rheumatol1996，35，：	1
5	Molecular cloning of interleukin-1 β from rainbow trout(Oncorhynchus mykiss) reveals no evidence of an ICE cut site显示文摘	Zou J Grabowski P S Cunningham C	1999	Cytokine1999，11，：	1
6	Properties of the C--H…H dihydrogen bond: An ab Initio and topological analysis显示文摘	Lipkowski P Grabowski S J Robinson T L	2004	J Phys Chem A2004，108，：	1
7	Nitric Oxide production in cells derived from the human joint显示文摘	GRABOWSKI P S MACPHERSON H RALSTON S H	1996	Br J Rheumatol1996，35，3：	1
8	显示文摘	GRABOWSKI N A HUGHES R P JAYNES B S	1986	Chem Commun1986，，：	1
9	Estimated enhance- ment of fish production resulting from restoring oyster reef habi- tat : quantitative valuation 显示文摘	Peterson C H Grabowski J H Powers S P	2003	Marine Ecology Progress2003，264，：	1
10	Stress-induced magnetic anisotropy in thick oriented NiZn-ferrite films on (100) MgO substrates 显示文摘	Dorsey P C Rappoli B J Grabowski K S	1997	J Appl Phys1997，81，10：	1
11	Rat retinal rigment epithelial cells express an inducible form of nitric oxide synthase and produce nitric oxide in response to inflammatory cytokines and activated T cells显示文摘	LIVERSIDGE J GRABOWSKI P RALSTON S	1994	Immunology1994，83，3：	1
12	Expression of nitric oxide synthase isoformas in bone and bone cell cultures 显示文摘	Helfrich M H Evans D E Grabowski P S etal	1997	Bone Miner Res1997，12，7：	1
13	Molecular cloning of interleukin I beta from rainbow trout Oncorhynchus mykiss reveals no evidence of an ice cut sit显示文摘	Zou J Grabowski P S Cunnigham C	1999	Cytokine1999，11，：	1
14	Estimated enhancement of fish production resulting from restoring oyster reef habitat: Quantitative valuation显示文摘	Peterson C H Grabowski J H Powers S P	2003	Marine Ecology Progress Series2003，264，：	1
15	Molecular cloning of interleukin-1 beta from rainbow trout(Oncorhynchus mykiss)reveals no evidence of an ICE cut site显示文摘	Zou J Grabowski P S Cunningham C	1999	Cytokine1999，11，：	1
16	Molecular cloning of interleukin 1β from rainbow trout Oncorhynchusmykiss reveals no evidence of an ICE cut site显示文摘	Zou J Grabowski P S Cunningham C	1999	Cytokine1999，11，：	1
17	Properties of the C--H…H dihydrogen bond: An ab initio and topological analysis 显示文摘	Lipkowski P Grabowski S J Robinson T L	2004	J Phys Chem A2004，108，10：	1
18	Properties of the C-H…H dihydrogen bond:an abinitio and topological analysis显示文摘	Lipkowski P Grabowski S J Robinson T L	2004	J Phys Chem A2004，108，10：	1
19	Properties of the C-H…H dihydrogen bond: An ab initio and topological analysis显示文摘	Lipkowski P Grabowski S J Robinson T L	2004	J Phys Chem A2004，108，10：	1
20	Effective asymmetric XML compression显示文摘	Skibinski P Grabowski S Swacha J	2008	Software Practice and Experience2008，38，10：	1

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