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254篇 您的检索式:作者名="Gregorio D D"
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1Portopulmonary hypertension and serum endothelin levels in hospitalized patients with cirrhosis显示文摘BACKGROUND:Cirrhosis is associated with several extrahepatic manifestations including portopulmonary hypertension (PPHT).Recent data suggest that endothelins (ETs) are related to the pathophysiology of PPHT.The study aimed to measure serum ET levels in hospitalized cirrhotic patients and to determine their association with PPHT and patient outcome.METHODS:Fifty-seven cirrhotic patients [43 males;median age 58 (28-87) years] underwent Doppler echocardiography.Patients with systolic pulmonary arterial pressure ≥40 mmHg and pulmonary acceleration time <100 ms were deemed to have PPHT.ET-1,2,and 3 serum levels were measured with an ELISA assay.All-cause mortality was recorded over a median period of 24 months.RESULTS:Nine out of 57 patients (15.8%) had PPHT.Among various clinical variables,only autoimmune hepatitis was associated with PPHT (OR=11.5;95% CI,1.58-83.4;P=0.01).ET-1 levels [9.1 (1.6-20.7) vs 2.5 (1.4-9.2) pg/mL,P=0.02] and the ET-1/ET-3 ratio [4.73 (0.9-22.4) vs 1.6 (0.3-10.7),P=0.02] were significantly higher in patients with PPHT than in those without.ET-2 and ET-3 levels did not differ between the two groups.There was no difference in survival between the two groups,although ET-1 levels were associated with an adverse outcome in Cox regression analysis (HR=1.11;95% CI,1.02-1.22;P=0.02 per unit increase in ET-1).CONCLUSION:Our data suggest that ET-1 and the ET-1/ET-3 ratio are elevated in patients with PPHT and that ET-1 is associated with a poor outcome irrespective of PPHT.Aristotelis Tsiakalos Gregorios Hatzis Ioannis Moyssakis Aggelos Karatzaferis Panayiotis D Ziakas George E Tzelepis 2011Hepatobiliary & Pancreatic Diseases International2011,10,4:7
2Effective bowel cleansing before colonoscopy: a randomized study of split-dosage versus non-split dosage regimens of high-volume versus low-volume polyethylene glycol solutions显示文摘Riccardo Marmo Gianluca Rotondano Giovanni Riccio Armando Marone Maria Antonia Bianco Italo Stroppa Anna Caruso Nicola Pandolfo Stefano Sansone Elena Gregorio Giuseppe D’Alvano Nicoletta Procaccio Pina Capo Clelia Marmo Livio Cipolletta 2010Gastrointestinal Endoscopy2010,,2:2
3Progress in breeding for salinity tolerance and associated abiotie stress in rice 显示文摘Gregorio G B Senadhira D Mendoza R D Manigbas R D Roxas N L Guerta C Q 2002Field Crops Research2002,76,2:1
4Mobility analysis of the 3-UPU parallel mechanism assembled for a pure translational motion显示文摘Gregorio R D Vincenzo P C 2002Translations of the ASM E Journal of Mechanical Design2002,124,6:1
5Characterization of Well Faceted Palladium Nano- particles Supported on Alumina by Transmission E- lectron Microscopy and FT-IR Spectroscopy of CO Adsorption显示文摘D GREGORIO F BISSON L ARMAROLI T 2009Appl Catal A: General2009,352,12:1
6How does for- eign direct investment affect economic growth 显示文摘Borensztein E Gregorio J D Lee J W 1998Jour- nal of International Economics1998,45,:1
7International new ventures:the cross-border nexus of individuals and opportunities显示文摘Gregorio D D Musteen M Thomas D E 0,,02:1
8A cel ular automata model for soil erosion by water显示文摘Ambrosio D Gregorio S D Gabriele S 0,,:1
9Characterizing the Saltol quantitative trait locus for salinity tolerance in rice 显示文摘Thomson M J Ocampo M Egdane J Rahman M A Sajise A G Adorada D L Tumimbang-Raiz E Blumwald E Seraj Z I Singh R K Gregorio G B Ismail A M 2010Rice2010,3,2:1
10Desenvolvimento Das Gonadas de Dermatobia hominis(Diptera:Cuterebridae)显示文摘LELLO E D GREGORIO E A TOLEDO L A 1985Mem Inst Oswaldo Cruz1985,80,2:1
11How does Foreign Direct Investment Affect Economic Growth? 显示文摘Borensztein E Gregorio J D Lee J - W 1998Journal of International Economics1998,45,:1
12MF59 adjuvant:the best insurance against influenza strain diversity显示文摘O'HAGAN D T RAPPUOLI R DE GREGORIO E 2011Expert Rev Vaccines2011,10,4:1
13Why do some universities generate more start-ups than others?显示文摘Di Gregorio D Shane S 2003Research Policy2003,,32:1
14Why do some universities generate more start-ups than others 显示文摘GREGORIO D D SHANE S 2003Research Policy2003,32,:1
15Progress in breeding for salinity tolerance and associated abiotic stresses in rice 显示文摘Gregorio G B Senadhira D Mendoza R D 2002Field Crops Research2002,76,:1
16Characterisation ofuranium(VI)sorption by two environmental fungal species using gammaspectrometry显示文摘GARGARELLO R CAVALITTO S GREGORIO D D 2008Environmental Technology2008,29,12:1
17Effect of crystallization rate on the formation of the polymorphs of solution cast poly (vinylidene fluoride) 显示文摘Gregorio R Borges D S 2008Polymer2008,49,:1
18Lipid emulsion is superior to vasopressin in a rodent model of resuscitation from toxininduced cardiac arrest显示文摘Di Gregorio G Schwartz D Ripper R et aL 2009Crit Care Med2009,37,3:1
19Breeding for trace mineral density in rice显示文摘Gregorio GB Senadhira D Htut T Graham R D 2000Food Nutr Bull2000,21,3:1
20How does foreign direct investment affect economic growth? 显示文摘Borenztein E Gregorio D Lee J 1998Journal of International Economics1998,45,1:1
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