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| 1 | China Patient-centered Evaluative Assessment of Cardiac Events Prospective Study of Acute Myocardial Infarction: Study Design显示文摘 | Rachel P Dreyer Xi Li Xue Du Nicholas S Downing Li Li Hai-Bo Zhang Fang Feng Wen-Chi Guan Xiao Xu Shu-Xia Li Zhen-Qiu Lin Frederick A Masoudi John A Spertus Harlan M Krumholz Li-Xin Jiang | 2016 | Chinese Medical Journal2016，，1： | 13 |
| 2 | 中国H3亚型流感病毒生态学与分子进化的研究显示文摘病毒生态学与分子进化是一门新兴的学科 ,研究病毒在各种环境中的关系 ,可以为今后病毒的研究与防治奠定基础。本研究首次详细对我国 14株鸭、鸡等禽流感和马、猪等动物的流感病毒的生态学与分子进化进行了分析研究 ,初步摸清了这些病毒在我国的流行与进化情况 ,为今后流感病毒疫苗的应用奠定了理论基础 。 | 崔尚金 李建伟 金红 李海燕 唐秀英 于康震 王秀荣 刘尚高 Y Guan K F Shortridge M Deries | 2002 | 中国预防兽医学报2002，24，2： | 5 |
| 3 | 心脏病及非心脏病患者降低舒张压的效果:收缩压干预试验结果分析显示文摘收缩压和舒张压低于何种阈值时心血管事件增多仍然不明确。应用收缩压干预试验(systolic blood pressure intervention trial,SPRINT)的数据,研究者评估了1519例心血管病患者和7574位非心血管病者的收缩压和舒张压与心血管事件之间的关系。 | 刘青 叶鹏 Khan NA Rabkin SW Zhao Y McAlister FA Park JE Guan M Chan S Humphries KH | 2018 | 中华高血压杂志2018，26，6： | 3 |
| 4 | Embryonic stem cell-derived chondrogenic differentiation in vitro: activation by BMP-2 and BMP-4显示文摘 | Jan Kramer Claudia Hegert Kaomei Guan Anna M Wobus Peter K Müller Jürgen Rohwedel | 2000 | Mechanisms of Development2000，，2： | 2 |
| 5 | Early diagnosis and therapeutic strategies for hepatocellular carcinoma:From bench to bedside显示文摘Hepatocellular carcinoma(HCC)is the fourth leading cause of cancer-related deaths worldwide.The prognosis of patients with HCC remains poor largely due to the late diagnosis and lack of effective treatments.Despite being widely used,alpha-fetoprotein serology and ultrasonography have limited diagnostic performance for early-stage HCC.The emergence of omics strategies has contributed to significant advances in the development of non-invasive biomarkers for the early diagnosis of HCC including proteins,metabolites,circulating tumor deoxyribonucleic acid,and circulating non-coding ribonucleic acid.Early diagnosis is beneficial to patients as it increases the proportion who can be treated with curative treatment,thus prolonging survival outcomes.Currently,multiple clinical trials involving locoregional,systemic therapies,and combinations of these modalities are changing therapeutic strategies for different stage HCC.Success in several preclinical trials that involve immunotherapeutic innovations has created the potential to complement and enforce other treatment strategies in the future.This review summarizes the most recent advances in noninvasive early molecular detection,current therapy strategies,and potential immunotherapeutic innovations of HCC. | Ming-Cheng Guan Ming-Da Wang Si-Yu Liu Wei Ouyang Lei Liang Timothy M Pawlik Qiu-Ran Xu Dong-Sheng Huang Feng Shen Hong Zhu Tian Yang | 2021 | World Journal of Gastrointestinal Oncology2021，13，4： | 2 |
| 6 | H5N1 influenza viruses isolated from geese in Southeastern China: evidence for genetic reassortment and interspecies transmission to duck 显示文摘 | Guan Y Peiris M Kong K F | 2002 | Virol2002，292，： | 1 |
| 7 | Clinical application of retrograde cerebral perfusion for brain protection during surgery of ascending aortic aneurysm--a report of 50 cases显示文摘 | Dong P Guan Y He M | 2002 | J Extra Corpor Technol2002，34，2： | 1 |
| 8 | PPAR gamma regulates adipoeyte cholesterol metabolism via oxidized LDL receptor 1显示文摘 | Chui P C Guan H P Lehrke M | 2005 | Clin Invest2005，115，8： | 1 |
| 9 | Expression of HIF-lalpha and VEGF in colorectal cancer: association with clinical outcomes and prognostic implieations显示文摘 | Cao D Hou M Guan YS | 2009 | BMC Cancer2009，9，： | 1 |
| 10 | Enhanced expression of cyclooxygenase - 2 in high grade human transitional cell bladder car- cinomas显示文摘 | Komhoff M Guan Y Shappell HW | 2000 | Am J Pathol2000，157，： | 1 |
| 11 | Tench farming in Chi- na: present status and future prospects 显示文摘 | Wang J X Min W Q E Guan M | 2006 | Aquaculture2006，，2006： | 1 |
| 12 | Cloning and expression of two carbonyl reductase-like 20 beta-hydroxysteroid dehydrogenase cDNAs in ovarian follicles of rainbow trout (Oncorhynchus mykiss) 显示文摘 | Guan G Tanaka M Todo T | 1999 | Biochem Biophys Res Commun1999，255，： | 1 |
| 13 | PTGF-beta,a type beta transforming growth factor(TGF-beta) superfamily member,is a p53 target gene that inhibits tumor cell growth via TGF-beta signaling pathway显示文摘 | Tan M Wang Y Guan K | 2000 | Proc Natl Acad Sci USA2000，97，1： | 1 |
| 14 | Long-range Ca2+ signaling from growth cone to soma mediates reversal of neuronal migration induced by slit-2显示文摘 | Guan CB Xu HT Jin M | 2007 | Cell2007，129，2： | 1 |
| 15 | Selected functionalproperties of extruded starch acetate and natural fibers foams显示文摘 | Guan J Fang Q Hanna M A | 2004 | Cereal Chem2004，81，： | 1 |
| 16 | A recently identified ovineBabesiain China:Serology and sero-epidemiology显示文摘 | GUAN G MA M LIU A | 2012 | Parasi-tol Int2012，61，4： | 1 |
| 17 | Blockade of hyaluronan inhibits IL-2-induced vascular leak syndrome and maintains effectiveness of IL-2 treatment for metastatic melanomaa 显示文摘 | Guan H Nagarkatti PS Nagarkatti M | 2007 | ] Lmmunol2007，179，6： | 1 |
| 18 | Mitoehondrial ferritin in neuro- degenerative diseases显示文摘 | Yang H Yang M Guan H | 2013 | Neurosci Res2013，77，12： | 1 |
| 19 | Characterization of a novel, water-soluble hydrogen sulfide - releasing molecule (GYY4137):unew insights into the biology of hydrogen sulfide显示文摘 | Li L Whiteman M Guan YY | 2008 | Circulation2008，117，18： | 1 |
| 20 | Focal adhesion kinase:A prominent determinant in breast cancer initiation,progression and metastasis显示文摘 | LUO M GUAN JL | | 0，，02： | 1 |
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