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| 1 | Texture analysis on parametric maps derived from dynamic contrast-enhanced magnetic resonance imaging in head and neck cancer显示文摘AIM: To investigate the merits of texture analysis on parametric maps derived from pharmacokinetic modeling with dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI) as imaging biomarkers for the prediction of treatment response in patients with head and neck squamous cell carcinoma(HNSCC). METHODS: In this retrospective study,19 HNSCC patients underwent pre- and intra-treatment DCEMRI scans at a 1.5T MRI scanner. All patients had chemo-radiation treatment. Pharmacokinetic modeling was performed on the acquired DCE-MRI images,generating maps of volume transfer rate(Ktrans) and volume fraction of the extravascular extracellular space(ve). Image texture analysis was then employed on maps of Ktrans and ve,generating two texture measures: Energy(E) and homogeneity.RESULTS: No significant changes were found for the mean and standard deviation for Ktrans and ve between pre- and intra-treatment(P > 0.09). Texture analysis revealed that the imaging biomarker E of ve was significantly higher in intra-treatment scans,relative to pretreatment scans(P < 0.04). CONCLUSION: Chemo-radiation treatment in HNSCC significantly reduces the heterogeneity of tumors. | Jacobus FA Jansen Yonggang Lu Gaorav Gupta Nancy Y Lee Hilda E Stambuk Yousef Mazaheri Joseph O Deasy Amita Shukla-Dave | 2016 | World Journal of Radiology2016，8，1： | 5 |
| 2 | Significant small-bowel lesions detected by alternative diagnostic modalities after negative capsule endoscopy显示文摘 | Aymer Postgate Edward Despott David Burling Arun Gupta Robin Phillips James O’Beirne David Patch Chris Fraser | 2008 | Gastrointestinal Endoscopy2008，，6： | 3 |
| 3 | Axial strain enhances osteotomy repair with a concomitant increase in connexin43 expression显示文摘The mechanical environment is known to influence fracture healing. We speculated that connexin43(Cx43) gap junctions, which impact skeletal homeostasis, fracture healing and the osteogenic response to mechanical load,may play a role in mediating the response of the healing bone to mechanical strain. Here, we used an established rat fracture model, which uses a 2 mm osteotomy gap stabilized by an external fixator, to examine the impact of various cyclical axial loading protocols(2%, 10%, and 30% strain) on osteotomy healing. We examined the presence of Cx43 in the osteotomy-healing environment and assessed how mechanical strain modulates Cx43 expression patterns in the callus. We demonstrated that increased cyclical axial strain results in increased radiographic and histologic bone formation. In addition, we show by immunohistochemistry that Cx43 is abundantly expressed in the healing callus, with the expression most robust in samples exposed to increased cyclical axial strain. These data are consistent with the concept that an increase in Cx43 expression by mechanical load may be part of the mechanisms by which mechanical forces enhances fracture healing. | Rishi R Gupta Hyunchul Kim Yu-Kwan Chan Carla Hebert Leah Gitajn David J Yoo Robert V O’Toole Adam H Hsieh Joseph P Stains | 2015 | Bone Research2015，3，2： | 2 |
| 4 | Comparative cardiopulmonary effects of xylazine and detomidine in goats显示文摘 | Dilipkumar D Sharma A K Gupta O P | 1998 | Indian Veterinary Journal1998，75，10： | 1 |
| 5 | Dynamic re- sponse oI an unbalanced rotor supported on ball bear- ings显示文摘 | TIWARI M GUPTA K PRAKASH O | 2000 | Journal of Sound and Vibration2000，238，5： | 1 |
| 6 | Effect of radial internal clearance of a ball bearing on the dynamics of a balanced hori-zontal rotor显示文摘 | Tiwari M Gupta K Prakash O | 2000 | Journal of Sound and Vibration2000，238，5： | 1 |
| 7 | Selective local anesthet- ic placement using ultrasound guidance and neurostimulation for in- fraclavicular brachial plexus block 显示文摘 | Bowens C Jr Gupta RK O' byrne WT | 2010 | Anesth Analg2010，110，5： | 1 |
| 8 | Synthesis and hydrogenation behaviour of graphitic nanofibres显示文摘 | Gupta B K Srivastava O N | 2000 | Int J Hydrogen Energy2000，25，： | 1 |
| 9 | Chronic nerve compression induces concurrent apoptosis and pro-liferation of Schwann cells 显示文摘 | Gupta R Steward O | 2003 | J Comp Neurol2003，461，2： | 1 |
| 10 | Effect of radial internal clearance of a ball bearing on the dynamics of a balanced horizontal rotor显示文摘 | Tiwari M Gupta K Prakash O | 2000 | Journal of Sound and Vibration2000，238，： | 1 |
| 11 | Superior outcomes in children compared with adults after microsurgical resection of brain arteriovenous malformations显示文摘 | Sanchez-Mejia Rene O Chennupati Sravana K Gupta | 2006 | Journal of Neurosurgery2006，105，2： | 1 |
| 12 | Dynamic response of an unbalanced rotor supported on bail bearings显示文摘 | Tiwari M Gupta K Prakash O | 2000 | Journal of Sound and Vibration2000，238，5： | 1 |
| 13 | Design of a Haptic Arm Exoskeleton for Training and Rehabilitation显示文摘 | A Gupta M K O'Malley | 2006 | IEEE/ASME Transactions on Mechatronics2006，11，3： | 1 |
| 14 | Effective treatment of rat adjuvant-induced arthritis by celastrol显示文摘 | R. Casc?o B. Vidal H. Raquel A. Neves-Costa N. Figueiredo V. Gupta J.E. Fonseca L.F. Moita | 2012 | Autoimmunity Reviews2012，，12： | 1 |
| 15 | Silk-on-silk layer-by-layer microcapsules 显示文摘 | SHCHEPELINA O DRACHUK I GUPTA M K | 2011 | Advanced Ma- terials2011，23，40： | 1 |
| 16 | Electrolytic plasma technology: Science and engineering-An overview 显示文摘 | Gupta P Tenhundfeld G Daiglf E O | 2007 | Surface and Coatings Technology2007，201，21： | 1 |
| 17 | Congenital fibrosarcoma of the chest wall: report of a cass显示文摘 | Gupta SS Singh O Sharma SS | 2010 | J Cutan Aesthet Surg2010，3，3： | 1 |
| 18 | Effect of radial internal clearance of a ball,bearing on the dynamica of a balanced horizontal rotor显示文摘 | TIWARI M GUPTA K PRAKASH O | 2000 | Journal of Sound and Vibration2000，238，5： | 1 |
| 19 | Follicular variant of papillary thyroid cancer: encapsulated, nonencapsulated, and diffuse: dis- tinct biologic and clinical entities 显示文摘 | Gupta S Ajise O Duhz L | 2012 | Arch Otolaryngol Head Neck Surg2012，138，3： | 1 |
| 20 | Association of biomarkers of inflammation and oxidative stress with the risk of chronic kidney disease in type 2 diabetes mellitus in North Indian population 显示文摘 | Gupta S Gambhir JK Kalra O | 2013 | J Diabetes Complications2013，27，6： | 1 |
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