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| 1 | Concurrent removal of intravitreal lens fragments after phacoemulsification with pars plana vitrectomy prevents development of retinal detachment显示文摘AIM: To evaluate the outcomes of 'concurrent vitrectomy' to retrieve dislocated lens fragment during phacoemulsification.METHODS: In a retrospective, observational case series, data of patients who underwent 'concurrent' pars plana vitrectomy(PPV) for dislocated lens fragments between the period 2000 and 2008 were reviewed. Data collected included patient demographics, pre-operative visual acuity, intra-operative occurrence of retinal breaks, duration of follow up, post-operative intraocular pressure, final best-corrected visual acuity(BCVA),presence of cystoid macular edema(CME) and occurrence of rhegmatogenous retinal detachment(RRD).· RESULTS: A total of 58 eyes of 58 patients were included in the study. At 12 mo the mean postoperative BCVA was log MAR 0.17(20/30) with a range of log MAR0 to 0.69(20/20 to 20/100), with 96.6%(56/58) of patients showing post- operative improvement in visual acuity(P =0.005). None of the patients developed postoperative retinal detachment, endophthalmitis or non-resolving uveitis at 12 mo.CONCLUSION: Our study results suggest concurrent PPV for retained lens fragments after cataract surgery is beneficial and may decrease the risk of glaucoma and prevent development of RRD. | Kakarla V Chalam Ravi K Murthy Joshua C Priluck Vijay Khetpal Shailesh K Gupta | 2015 | International Journal of Ophthalmology(English edition)2015，8，1： | 4 |
| 2 | Cell-type specificity of β-actin expression and its clinicopathological correlation in gastric adenocarcinoma显示文摘AIM:To investigate cell type specific distribution ofβ-actin expression in gastric adenocarcinoma and its correlation with clinicopathological parameters.METHODS:β-actin is a housekeeping gene,frequently used as loading control,but,differentially expresses in cancer.In gastric cancer,an overall increased expression ofβ-actin has been reported using tissue disruptive techniques.At present,no histological data is available to indicate its cell type-specific expression and distribution pattern.In the present study,we analyzedβ-actin expression and distribution in paired normal and tumor tissue samples of gastric adenocarcinoma patients using immunohistochemistry(IHC),a tissue non-disruptive technique as well as tissue disruptive techniques like reverse transcriptase-polymerase chain reaction(RT-PCR)and western blotting.Correlation ofβ-actin level with clinicopathological parameters was done using univariate analysis.RESULTS:The results of this study showed significant overexpression,at both mRNA and protein level in tumor tissues as confirmed by RT-PCR(1.47±0.13 vs2.36±0.16;P<0.001)and western blotting(1.92±0.26 vs 2.88±0.32;P<0.01).IHC revealed thatβ-actin expression is majorly distributed between epithelial and inflammatory cells of the tissues.Inflammatory cells showed a significantly higher expression compared to epithelial cells in normal(2.46±0.13 vs 5.92±0.23,P<0.001),as well as,in tumor tissues(2.79±0.24 vs6.71±0.14,P<0.001).Further,comparison of immunostaining between normal and tumor tissues revealed that both epithelial and inflammatory cells overexpressβ-actin in tumor tissues,however,significant difference was observed only in inflammatory cells(5.92±0.23vs 6.71±0.14,P<0.01).Moreover,combined expression in epithelial and inflammatory cells also showed significant increase(4.19±0.15 vs 4.75±0.14,P<0.05)in tumor tissues.In addition,univariate analysis showed a positive correlation ofβ-actin level of inflammatory cells with tumor grade(P<0.05)while epithelial cells exhibited negative correlation(P>0.05).CONCLUSION:In gastric cancer,β-actin showed an overall higher expression predominantly contributed by inflammatory or tumor infiltrating immune cells of the tissue microenvironment and correlates with tumor grade. | Shafqat A Khan Monica Tyagi Ajit K Sharma Savio G Barreto Bhawna Sirohi Mukta Ramadwar Shailesh V Shrikhande Sanjay Gupta | 2014 | World Journal of Gastroenterology2014，20，34： | 2 |
| 3 | Wavelet -based characterization of design ground motions 显示文摘 | Mukherjee S Gupta V K | 2002 | Earthquake Engineering and Structural Dynamics2002，31，5： | 1 |
| 4 | Removal of lead and chromium from wastewater using bagasse fly ash: a sugar industry waste 显示文摘 | Gupta V K Ali Imran | 2004 | Journal of Colloid and Interface Science2004，271，2： | 1 |
| 5 | Influence of zinc on calcium magnesium, sodium, potassium and phosphorus nutrition of soybeam(Glyeine max) in sodie soils 显示文摘 | Gupta S P Gupta V K | 1984 | Indian Journal of Ecology1984，11，2： | 1 |
| 6 | Nutrition of maize as Influenced by zinc and nitrogen carriers 显示文摘 | Gupta V K and Patalia B S | 1995 | J Indian Soc Sci1995，41，1： | 1 |
| 7 | A contribution to the geology of Northeastern Kumaun, with special reference to the Hercynian gap in Tethys Himalaya显示文摘 | Valdiya K S Gupta V J | 1972 | Himalaya Geology1972，2，： | 1 |
| 8 | Knowledge flows and the structure of control within multinational corporations显示文摘 | Gupta A K Govindarajan V | 1991 | Academy of Management Review1991，16，4： | 1 |
| 9 | A Representation of an IUH from Geomorphology显示文摘 | V K Gupta | 1980 | Water Resources Research1980，16，5： | 1 |
| 10 | Evolution approach for effective and efficient global minimization显示文摘 | DUAN Q Y GUPTA V K SOROOSHIAN S S | 1993 | Journal of Optimization Theory1993，76，3： | 1 |
| 11 | Shuffled complex evolution approach for effective and efficient global minimization显示文摘 | Duan Q Y Gupta V K Sorooshian S | 1993 | Journal of Optimization Theory and Applications1993，76，3： | 1 |
| 12 | Knowledge flows within multinational corporations显示文摘 | Gupta A K Govindarajan V | 2000 | Strategic Management Jour- nal2000，21，4： | 1 |
| 13 | 'llae ehemopreventive and chemothera- peutic potentials of Tea polyphenols 显示文摘 | THAKUR V S GUPTA K GUPTA S | 2012 | Current Pharmaceutical Biotech- nology2012，13，1： | 1 |
| 14 | MnO2 decorated graphene nanoribhons with superior permittivity and excel- lent microwave shielding properties 显示文摘 | Gupta T K Singh B P Singh V N | 2014 | J Mater Chem A2014，2，12： | 1 |
| 15 | Rapid synthesis of graft co- polymers from natural cellulose fiber 显示文摘 | Thakur V K Thakur M K Gupta R K | 2013 | Carbohydrate Polymers2013，98，： | 1 |
| 16 | Optimal use of the SCE - UA global optimization method for calibrating watershed models显示文摘 | DUAN Q SOROOSHIAN S GUPTA V K | 1994 | Journal of Hydrology1994，158，34： | 1 |
| 17 | Normal and oblique impact of energy projectile on mild steel plates显示文摘 | Gupta N K Madhu V | 1992 | International Journal of Impact Engineering1992，12，3： | 1 |
| 18 | Non - stationary seismic response of MDOF systems by wavelet transform显示文摘 | Basu B Gupta V K | 1997 | Earthquake Engineering and Structural Dynamics1997，26，12： | 1 |
| 19 | Artificial neural networks for RF and microwave design-fi'om theory to practice显示文摘 | ZHANG Q J GUPTA K C DEVABHAKTUNI V K | 2003 | IEEE Trans Microwave Theory Tech2003，51，： | 1 |
| 20 | Recent advances on surface engineering of magnetic iron oxide nanoparticles and their biomedical applications 显示文摘 | GUPTA A K NAREGALKAR R R VAIDYA V D | 2007 | Nanornedicine2007，2，1： | 1 |
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