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| 1 | Chronic ischemic mitral valve regurgitation and surgical perspectives显示文摘Chronic ischemic mitral valve regurgitation is a result of disturbed left ventricular geometry secondary to myocardial ischemia in the absence of intrinsic mitral valve pathology. It is a common complication after myocardial infarction, and patients who have ischemic mitral regurgitation(IMR) have a worse prognosis compared to patients who have ischemic heart disease alone, and this is directly related to the severity of IMR. Medical therapy has limited efficacy, and surgical options including various repair techniques and valve replacement had been tried with variable success. Still there is intense debate among surgeons whether to interfere with moderate degree IMR at the time of coronary artery revascularization. | Salah Eldien Altarabsheh Salil V Deo Abeer Rababa'h Yagthan M Obeidat Osama Haddad | 2018 | World Journal of Cardiology2018，10，10： | 5 |
| 2 | A randomized open-label trial of on-demand rabeprazole vs ranitidine for patients with non-erosive reflux disease显示文摘AIM:To compare the efficacy of the proton-pump inhibitor,rabeprazole,with that of the H 2-receptor antagonist,ranitidine,as on-demand therapy for relieving symptoms associated with non-erosive reflux disease(NERD).METHODS:This is a single center,prospective,randomized,open-label trial of on-demand therapy with rabeprazole(group A) vs ranitidine(group B) for 4 wk.Eighty-three patients who presented to the American University of Beirut Medical Center with persistent gastroesophageal reflux disease(GERD) symptoms and a normal upper gastrointestinal endoscopy were eligible for the study.Patients in group A(n = 44) were allowed a maximum rabeprazole dose of 20 mg twice daily,while those in group B(n = 39) were allowed a maximum ranitidine dose of 300 mg twice daily.Efficacy was assessed by patient evaluation of global symptom relief,scores of the SF-36 quality of life(QoL) questionnaires,total number of pills used,and number of medication-free days.RESULTS:Among the 83 patients who were enrolled in the study,76 patients(40 in the rabeprazole group and 36 in the ranitidine group) completed the 4-wk trial.Baseline characteristics were comparable between both groups.After 4 wk,there was no significant difference in the subjective global symptom relief between the rabeprazole and the ranitidine groups(71.4% vs 65.4%,respectively;P = 0.9).There were no statistically significant differences between mean cumulative scores of the SF-36 QoL questionnaire for the two study groups(rabeprazole 22.40 ± 27.53 vs ranitidine 17.28 ± 37.06;P = 0.582).There was no significant difference in the mean number of pills used(rabeprazole 35.70 ± 29.75 vs ranitidine 32.86 ± 26.98;P = 0.66).There was also no statistically significant difference in the mean number of medication-free days between both groups.CONCLUSION:Rabeprazole has a comparable efficacy compared to ranitidine when given on-demand for the treatment of NERD.Both medications were associated with improved quality of life. | Abdallah A Kobeissy Jana G Hashash Faek R Jamali Assaad M Skoury Reham Haddad Sarah El-Samad Rami Ladki Rola Aswad Assaad M Soweid | 2012 | World Journal of Gastroenterology2012，18，19： | 4 |
| 3 | 树突状细胞自然杀伤细胞凝集素群受体1促进小鼠动脉粥样硬化的发展显示文摘动脉粥样硬化发展过程中的坏死核心形成与慢性炎症反应有关,其促进斑块发展加快和不稳定。然而,坏死与动脉粥样硬化发展之间的分子生物学联系机制尚未完全清楚。 | 刘莉 叶鹏 Haddad Y Lahoute C Clément M Laurans L Metghalchi S Lynda Z Giraud A Loyer X Vandestienne M Wain-Hobson J Esposito B Potteaux S Ait-Oufella H Tedgui A Mallat Z Taleb S | 2017 | 中华高血压杂志2017，25，8： | 3 |
| 4 | 肺动脉高压患者的负荷适应性显示文摘已知右心室对压力超负荷的适应是肺动脉高压(pulmonary arterial hypertension,PAH)患者预后的主要影响因素。为了评估右心室适应和负荷之间的关系,然后比较PAH中不同负荷适应性指数的预后价值,Amsallem及其同事纳入推导队列(n=85)和验证队列(n=200),使用3种方法评估负荷适应性:①脑室动脉耦合的替代物(例如右心室面积变化/收缩末期面积); | 刘莉 叶鹏 Amsallem M Boulate D Aymami M Guihaire J Selej M Huo J Denault AY McConnell MV Schnittger I Fadel E Mercier O Zamanian RT Haddad F | 2017 | 中华高血压杂志2017，25，8： | 2 |
| 5 | Enhanced expression of the CD71 mesangial IgA1 receptor in Berger disease and Henoch-Schonlein nephritis:Association between CD71 expression and IgA deposits显示文摘 | Haddad E Moura IC Arcos-Fajardo M | 2003 | Am SocNephro2003，14，2： | 1 |
| 6 | Docetaxel,cisplatin,5-fluorouracil (TPF)-based induction chemotherapy for head and neck cancer and the case for sequential,combined-modality treatment显示文摘 | Haddad R Tishler R B Norris C M | 2003 | Oncologist2003，8，1： | 1 |
| 7 | Multidrug resistance proteins do not predict benefit of adjuvant chemotherapy in patients with completely resected non-small cell lung cancer:International adjuvant lung cancer trial biologic program显示文摘 | Filipits M Haddad V Schmid K | 2007 | Clin Cancer Res2007，13，13： | 1 |
| 8 | Treatment of B-lymphoproliferative disorder with a monoclonal anti-interlenkin-6 antibody in 12 patients: a multicenter phase 1-2 clinical trial显示文摘 | Haddad E Paezesny S Leblond V Seigneurin JM Stern M Achkar A | 2001 | Blood2001，97，6： | 1 |
| 9 | A fundamental criterion for the application of rotor casing treatment显示文摘 | Greitzer E M Nikkanen J P Haddad D E | 1979 | Journal of Fluids Engineering1979，101，2： | 1 |
| 10 | 显示文摘 | BREADMORE M C MACKA M HADDAD P R | 1999 | Electrophoresis1999，20，10： | 1 |
| 11 | Enhanced expression of the CD71 mesangial IgA1 receptor in Berger and Henoch-Schonlein nephritis:association between CD71 expression and IgA deposits显示文摘 | Haddad E Moura IC Arcos-Fajardo M | 2003 | J Am Soc Nephrology2003，14，2： | 1 |
| 12 | Optimum dietary crude protein level for finishing Awassi lambs显示文摘 | Haddad S G Nasr R E Muwalla M M | 2001 | 39(1): 41-462001，39，1： | 1 |
| 13 | The Effect of Alcohol Fumigation on Diesel Engine Performance and Emissions显示文摘 | Abu-Qudais M Haddad O Qudaisat M | 2000 | Energy Conversion & Management2000，，41： | 1 |
| 14 | Ge- nomic amplification of the human telomerase gene (TERC)in pap smears predicts the development of cervical cancer 显示文摘 | Heselmeyer - Haddad K Sommerfeld K White N M | 2005 | Am J Patho12005，166，4： | 1 |
| 15 | Controller Design with Regional Pole Constraints显示文摘 | Wassim M Haddad Dennis S Bernstein | 1992 | 37 (1) :54 -691992，37，1： | 1 |
| 16 | Electrokinetic supercharging for on-line preconcentration of seven non-steroidal anti-inflammatory drugs in water samples显示文摘 | Dawod M Breadmore MC Guijt RM Haddad PR | 2008 | Journal of Chromatography A2008，，： | 1 |
| 17 | 查看详情显示文摘 | Shaw M J Haddad P R | | 0，，03： | 1 |
| 18 | Performance of earthing systems of low resistivity soils 显示文摘 | Nor N M Haddad A Griffiths H | 2006 | IEEE Transactions on PWRD2006，21，4： | 1 |
| 19 | Highly sensitive indirect photometric detection of cations by capillary electrophoresis with the cationic dye chrysoidine显示文摘 | C Johns M Macka P R Haddad | 2003 | J Chromatogr A2003，997，： | 1 |
| 20 | Robust H∞ controller for discrete-time systems with time delay显示文摘 | V Kapila V M Haddad | | 0，，： | 1 |
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