|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Colonoscopic yield of colorectal neoplasia in daily clinical practice显示文摘AIM:To assess the prevalence and location of ad-vanced neoplasia in patients undergoing colonoscopy,and to compare the yield per indication.METHODS:In a multicenter colonoscopy survey (n = 18 hospitals) in the Amsterdam area (Northern Holland),data of all colonoscopies performed during a three month period in 2005 were analyzed. The location and the histological features of all colonic neoplasia were recorded. The prevalence and the distribution ofadvanced colorectal neoplasia and differences in yield between indication clusters were evaluated. Advanced neoplasm was defi ned as adenoma > 10 mm in size,with > 25% villous features or with high-grade dyspla-sia or cancer.RESULTS:A total of 4623 eligible patients underwent a total colonoscopy. The prevalence of advanced neo-plasia was 13%,with 281 (6%) adenocarcinomas and 342 (7%) advanced adenomas. Sixty-seven percent and 33% of advanced neoplasia were located in the distal and proximal colon,respectively. Of all patients with right-sided advanced neoplasia (n = 228),51% had a normal distal colon,whereas 27% had a syn-chronous distal adenoma. Ten percent of all colono-scopies were performed in asymptomatic patients,7% of whom had advanced neoplasia. In the respective procedure indication clusters,the prevalence of right-sided advanced neoplasia ranged from 11%-57%. CONCLUSION:One out of every 7-8 colonoscopies yielded an advanced colorectal neoplasm. Colonoscopy is warranted for the evaluation of both symptomatic and asymptomatic patients. | Jochim S Terhaar sive Droste Mike E Craanen Rene WM van der Hulst Joep F Bartelsman Dick P Bezemer Kim R Cappendijk Gerrit A Meijer Linde M Morsink Pleun Snel Hans ARE Tuynman Roy LJ van Wanrooy Eric IC Wesdorp Chris JJ Mulder | 2009 | World Journal of Gastroenterology2009，15，9： | 6 |
| 2 | Metabolic syndrome does not affect sustained virologic response of direct-acting antivirals while hepatitis C clearance improves hemoglobin A1c显示文摘AIM To determine whether successful treatment with direc-tacting antivirals(DAA) is associated with improvements in hemoglobin A1 c(HbA1 c) and if type 2 diabetes mellitus(T2 DM) or metabolic syndrome affects sustained virologic response(SVR).METHODS We performed a retrospective analysis of all hepatitis C virus(HCV) patients at the VA Greater Los Angeles Healthcare System treated with varying DAA therapy between 2014-2016. Separate multivariable logistic regression was performed to determine predictors of HbA1 c decrease ≥ 0.5 after DAA treatment and predictors of SVR 12-wk post treatment(SVR12).RESULTS A total of 1068 patients were treated with DAA therapy between 2014-2016. The presence of T2 DM or metabolic syndrome did not adversely affect SVR12. 106 patients had both HCV and T2 DM. Within that cohort,patients who achieved SVR12 had lower mean HbA1 c pre treatment(7.35 vs 8.60,P = 0.02),and lower mean HbA1 c post-treatment compared to non-responders(6.55 vs 8.61,P = 0.01). The mean reduction in HbA1 c after treatment was greater for those who achieved SVR12 than for non-responders(0.79 vs 0.01,P = 0.03). In adjusted models,patients that achieved SVR12 were more likely to have a HbA1 c decrease of ≥ 0.5 than those that did not achieve SVR12(adjusted OR = 7.24,95%CI: 1.22-42.94). CONCLUSION In HCV patients with T2 DM,successful treatment with DAA was associated with a significant reduction in HbA1 c suggesting that DAA may have a role in improving insulin sensitivity. Furthermore,the presence of T2 DM or metabolic syndrome does not adversely affect SVR12 rates in patients treated with DAA. | Tien S Dong Elizabeth S Aby Jihane N Benhammou Jenna Kawamoto Steven-Huy Han Folasade P May Joseph R Pisegna | 2018 | World Journal of Hepatology2018，10，9： | 4 |
| 3 | 油炸食品与心血管病风险和全因死亡率的关系:观察性研究的荟萃分析显示文摘研究者进行了一项荟萃分析,包括剂量反应分析,以定量确定油炸食品摄入与普通成年人群心血管病风险和全因死亡率之间的关系。方法:研究者在PubMed、EMBASE和Web of Science上检索2020年4月11日之前的所有文章。应用随机效应模型估计总的相对危险度(relative risks,RR)和95%CI。结果:与最低油炸食品摄入量相比,最高摄入量者主要心血管事件的总RR(95%CI)=1.28(1.15~1.43),n=17,I^(2)=82.0%,其中前瞻性研究:1.24(1.12~1.38),n=13,I^(2)=75.7%. | 刘青(译) 练桂丽(审校) Qin P Zhang M Han M Liu D Luo X Xu L Zeng Y Chen Q Wang T Chen X Zhou Q Li Q Qie R Wu X Li Y Zhang Y Wu Y Hu D Hu F | 2021 | 中华高血压杂志2021，29，2： | 3 |
| 4 | Ohmic contact properties of multi-metal films on n-type 4H-SiC显示文摘 | Yang Y T Wang P | 2007 | Chinese Journal of Semiconductors2007，28，2： | 1 |
| 5 | Proinflammatory cytokines cause NO dependent and independent changes in expression and localization of tight junction proteins in intestinal epithelial cells显示文摘 | Han X Fink M P Delude R L | 2003 | Shock2003，19，3： | 1 |
| 6 | Assessment of erosion haz- ard with the USLE and GIS A ease study of the Upper Ewaso Nglro North basin of Kenya显示文摘 | Bancy M Mati Royston P C Morgan Francis N Gichuki John N Quinton Tim R Brewer Hans P l iniger | 2000 | lnternation Journal of Applied Earth Ob- servation and Geoinformation2000，2，2： | 1 |
| 7 | Palladium-catalyzed dehydrogenative cross-couplings of benzazoles with azoles显示文摘 | Han W Mayer P Ofial A R | 2011 | Angew Chem Int Ed2011，50，9： | 1 |
| 8 | The effect of dehydration and ion stress on carbon dioxide fixation in drought-tolerant phototrophic micro-organisms 显示文摘 | Ben De W Hans C P W Luuc R M | 1990 | FEMS Microhiol Lett1990，74，1： | 1 |
| 9 | The principal target of rapamycin-induced p70s6k inactivation is a novel phosphorylation site within a conserved hydrophobic domain显示文摘 | Pearson R B Dennis P B Han J W | 1995 | EMBO J1995，14，21： | 1 |
| 10 | Modal analysis of rotating shaft a body-fixed axis formulation approach显示文摘 | HAN R P S ZU J W Z | 1992 | Journal of Sound and Vibration1992，156，1： | 1 |
| 11 | Population variation in growth and 15-year-old shoot elongation along geographic and climatic gradients in black spruce in Alberta显示文摘 | Wei R P Han S D Dhir N K | 2004 | Canada Journal of Forest Research2004，34，8： | 1 |
| 12 | Natural frequencies and normal modes of a spinning beam with general boundary conditions 显示文摘 | Zu J W Han R P | 1992 | J Appl Mech-Trans ASME1992，59，： | 1 |
| 13 | Grain growth in Mn- doped ZnO显示文摘 | Han J Mantas P Q Senos A M R | 2000 | J Eur Ceram Soc2000，20，16： | 1 |
| 14 | Chaotic motion of a horizontal impact pair显示文摘 | Han R P S Luo A C J Deng W | 1995 | Journal of Sound and Vibration1995，181，2： | 1 |
| 15 | Per- formance of artificially roughened solar air heaters--A review 显示文摘 | Vishavjeet Singh Hans R P Saini J S Saini | 2009 | Renewable and Sustainable Energy Reviews2009，，13： | 1 |
| 16 | A novel expression system for recombinant marine mussel adhesive protein Mefpl using a truncated OmpA signal peptide显示文摘 | Lee S J Han Y H Nam B H Kim Y O Reeves P R | 2008 | Mol Cells2008，26，： | 1 |
| 17 | Trends in online networking among South Korean politicians -- A mixed-method approach 显示文摘 | Han W P Kluver R | 2009 | Government Information Quarterly2009，26，3： | 1 |
| 18 | Succession of phytoplankton functional groups regulated by monsoonal hydrology in a large canyon-shaped reservoir显示文摘 | Xiao L J Wang T Hu R Han B P Wang S Qian X Padisák J | 2011 | Water Research2011，45，16： | 1 |
| 19 | Novel synthesis and photocatalytic performance of Bi VO4 with tunable morphologies and macroscopic structures显示文摘 | WU Q HAN R CHEN P | 2015 | Mat Sci Semicon Proc2015，38，： | 1 |
| 20 | Within-and between-stand distribution of attacks by pine weevil 显示文摘 | Lars W H Hans P R Jonas Geldmann | 2005 | Scandinavian Journal of Forest Research2005，20，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员