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| 1 | 临床实践指南应当包含治疗负担显示文摘医疗方案的实施需要花费大量时间和精力,给慢性病患者带来巨大负担。然而,临床实践指南高度重视的是得到某些临床结果(如呼吸急促减少或存活率增加),传统指南的建议也是从同样角度提出的。最近的指南会考虑患者的价值观以及指南建议行为的可接受性和可行性,但对治疗负担没有明确规定。这使患者很难根据自己的价值观和能力对治疗做出明智的决定。 | Claudia C Dobler Nathan Harb Catherine A Maguire Carol L Armour Courtney Coleman M Hassan Murad 邓璇(译) 莫云凌(校) | 2019 | 英国医学杂志中文版2019，22，3： | 3 |
| 2 | Split-dose menthol-enhanced PEG vs PEG-ascorbic acid for colonoscopy preparation显示文摘AIM:To compare the efficacy and palatability of 4L polyethylene glycol electrolyte(PEG)plus sugar-free menthol candy(PEG+M)vs reduced-volume 2 L ascorbic acid-supplemented PEG(Asc PEG).METHODS:In a randomized controlled trial setting,ambulatory patients scheduled for elective colonoscopy were prospectively enrolled.Patients were randomized to receive either PEG+M or Asc PEG,both splitdosed with minimal dietary restriction.Palatability was assessed on a linear scale of 1 to 5(1=disgusting;5=tasty).Quality of preparation was scored by assignment-blinded endoscopists using the modified Aronchick and Ottawa scales.The main outcomes were the palatability and efficacy of the preparation.Secondary outcomes included patient willingness to retake the same preparation again in the future and completion of the prescribed preparation.RESULTS:Overall,200 patients were enrolled(100patients per arm).PEG+M was more palatable than Asc PEG(76%vs 62%,P=0.03).Completing the preparation was not different between study groups(91%PEG+M vs 86%Asc PEG,P=0.38)but more patients were willing to retake PEG+M(54%vs 40%respectively,P=0.047).There was no significant difference between PEG+M vs Asc PEG in adequate cleansing on both the modified Aronchick(82%vs77%,P=0.31)and the Ottawa scale(85%vs 74%,P=0.054).However,PEG+M was superior in the left colon on the Ottawa subsegmental score(score0-2:94%for PEG+M vs 81%for Asc PEG,P=0.005)and received significantly more excellent ratings than Asc PEG on the modified Aronchick scale(61%vs 43%,P=0.009).Both preparations performed less well in afternoon vs morning examinations(inadequate:29%vs 15.2%,P=0.02).CONCLUSION:4 L PEG plus menthol has better palatability and acceptability than 2 L ascorbic acidPEG and is associated with a higher rate of excellentpreparations;Clinicaltrial.gov identifier:NCT01788709. | Ala I Sharara Ali H Harb Fayez S Sarkis Jean M Chalhoub Rami Badreddine Fadi H Mourad Mahmoud Othman Omar Masri | 2015 | World Journal of Gastroenterology2015，21，6： | 2 |
| 3 | Application of bifurcation theory to subsynchronous resonance in power systems 显示文摘 | Nayfeh A M Harb A M Chin C M | 1998 | International Journal of Bifurcation and Chaos1998，8，1： | 1 |
| 4 | The safety ofradiofrequen- cy thermal ablation in the treatment of live malignancies显示文摘 | Casaril A Abu Hilal M Harb A | 2012 | Eur J Surg Oncol2012，34，6： | 1 |
| 5 | Molecular and physiological analysis of drought stress in Arabidopsis reveals early responses leading to acclimation in plant growth 显示文摘 | Harb A Krishnan A Ambavaram M M R | 2010 | Plant Physiology2010，154，： | 1 |
| 6 | The safety of radiofre-quency thermal ablation in the treatment of liver malignancies显示文摘 | Casaril A Abu Hilal M Harb A | 2008 | Eur J Surg Oncol2008，34，6： | 1 |
| 7 | Nonlinear control of permanent magnet stepper motors显示文摘 | Harb Ahmad M Zaher Ashraf A | 2004 | Communications in Nonlinear Science and Numerical Simulation2004，，1： | 1 |
| 8 | The safety of radiofrequency thermal ablation in the treatment of liver malignancies显示文摘 | Casaril A Abu-Hilal M Harb A | 2008 | Eur J Surg Oncol2008，34，6： | 1 |
| 9 | Hepatic splenosis mimic- king HCC in a patient with hepatitis C liver cirrhosis and mildly raised alpha fetoprotein; the important role of explorative laparos- copy显示文摘 | Abu Hilal M Harb A Zeidan B | 2009 | World J Surg Oncol2009，7，： | 1 |
| 10 | Effects of lasalocid and protein levels on the performance of Awassi lambs显示文摘 | MUWALLA M M HARB M Y CROSBY T F | 1998 | Small Ruminant Res1998，28，97： | 1 |
| 11 | On nonlinear control design for autonomous chaotic systems of integer and fractional orders,Chaos显示文摘 | HARB A M | 2003 | Solitons and Fractals2003，18，： | 1 |
| 12 | The role of the scavenger receptor CD36 in regulating mononuclear phago- cyte trafficking to atherosclerotic lesions and vascular in- flammation显示文摘 | Harb D Bujold K Febbraio M | 2009 | Cardiovasc Res2009，83，1： | 1 |
| 13 | The role of the scavenger receptor CD36 in regulating mononuclear phagocyte trafficking to atherosclerotic lesions and vascular inflammation显示文摘 | Harb D Bujold K Febbraio M | 2009 | Cardiovasc Res2009，83，1： | 1 |
| 14 | Wave function microscopy of quasibound atomic states 显示文摘 | Cohen S Harb M M Ollagnier A | 2013 | Physical Review Letters2013，110，18： | 1 |
| 15 | Controlling chaos in Josephson junction using nonlinear backstepping controller显示文摘 | Harb A M Harb B A | 2006 | IEEE Trans Appl Supercond2006，16，4： | 1 |
| 16 | Generation of Squeezing in Higher Order Hermite-Gaussian Modes with an Opti?cal Parametric Amplifier显示文摘 | Lassen M Delaubert V Harb C C | 2006 | J ournal of European Optical Society2006，1，06： | 1 |
| 17 | Toxoplasma gondii Hsp90 is a potential drug target whose expression and subcellular localization are developmentally regulated显示文摘 | Echeverria P C Matrajt M Harb O S | 2005 | J Mol Biol2005，350，4： | 1 |
| 18 | Chaos and bifurcation in a third- order phase-locked loop显示文摘 | Harb B A Harb A M | 2004 | Chaos Solitons and Frac- tals2004，19，： | 1 |
| 19 | Dynamic response analysis procedure for landfills with geosynthetic liners显示文摘 | YEGIAN M K HARB J N KADAKAL U | 1998 | Journal of Geotechnical and Geoenviromental Engineering ASCE1998，124，10： | 1 |
| 20 | A case of foot drop as an expression of brain metastases显示文摘 | Djekidel M Harb W | | 0，，： | 1 |
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