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| 1 | Effect of nitrogen fertilization on yield, N content, and nitrogen fixation of alfalfa and smooth bromegrass grown alone or in mixture in greenhouse pots显示文摘Planting grass and legume mixtures on improved grasslands has the potential advantage of realizing both higher yields and lower environmental pollution by optimizing the balance between applied N fertilizer and the natural process of legume biological nitrogen fixation. However, the optimal level of N fertilization for grass-legume mixtures, to obtain the highest yield, quality, and contribution of N2 fixation, varies with species. A greenhouse pot experiment was conducted to study the temporal dynamics of N2 fixation of alfalfa(Medicago sativa L.) grown alone and in mixture with smooth bromegrass(Bromus inermis Leyss.) in response to the addition of fertilizer N. Three levels of N(0, 75, and 150 kg ha–1) were examined using 15N-labeled urea to evaluate N2 fixation via the 15 N isotope dilution method. Treatments were designated N0(0.001 g per pot), N75(1.07 g per pot) and N150(2.14 g per pot). Alfalfa grown alone did not benefit from the addition of fertilizer N; dry matter was not significantly increased. In contrast, dry weight and N content of smooth bromegrass grown alone was increased significantly by N application. When grown as a mixture, smooth bromegrass biomass was increased significantly by N application, resulted in a decrease in alfalfa biomass. In addition, individual alfalfa plant dry weight(shoots+roots) was significantly lower in the mixture than when grown alone at all N levels. Smooth bromegrass shoot and root dry weight were significantly higher when grown with alfalfa than when grown alone, regardless of N application level. When grown alone, alfalfa's N2 fixation was reduced with N fertilization(R2=0.9376, P=0.0057). When grown in a mixture with smooth bromegrass, with 75 kg ha–1 of N fertilizer, the percentage of atmospheric N2 fixation contribution to total N in alfalfa(%Ndfa) had a maximum of 84.07 and 83.05% in the 2nd and 3rd harvests, respectively. Total 3-harvest %Ndfa was higher when alfalfa was grown in a mixture than when grown alone(shoots: |t|=3.39, P=0.0096; root: |t|=3.57, P=0.0073). We believe this was due to smooth bromegrass being better able to absorb available soil N(due to its fibrous root system), resulting inlower soil N availability and allowing alfalfa to develop an effective N2 fixing symbiosis prior to the 1st harvest. Once soil N levels were depleted, alfalfa was able to fix N2, resulting in the majority of its tissue N being derived from biological nitrogen fixation(BNF) in the 2nd and 3rd harvests. When grown in a mixture, with added N, alfalfa established an effective symbiosis earlier than when grown alone; in monoculture BNF did not contribute a significant portion of plant N in the N75 and N150 treatments, whereas in the mixture, BNF contributed 17.90 and 16.28% for these treatments respectively. Alfalfa has a higher BNF efficiency when grown in a mixture, initiating BNF earlier, and having higher N2 fixation due to less inhibition by soil-available N. For the greatest N-use-efficiency and sustainable production, grass-legume mixtures are recommended for improving grasslands, using a moderate amount of N fertilizer(75 kg N ha–1) to provide optimum benefits. | XIE Kai-yun LI Xiang-lin HE Feng ZHANG Ying-jun WAN Li-qiang David B Hannaway WANG Dong QIN Yan Gamal M A Fadul | 2015 | Journal of Integrative Agriculture2015，14，9： | 5 |
| 2 | Importance of integrating nanotechnology with pharmacology and physiology for innovative drug delivery and therapy - an illustration with, firsthand examples显示文摘纳米技术在药交货广泛地被使用了改进各种各样的疾病的治疗学的结果。巨大的努力在与他们的生物命运和函数的关系集中于 nanoparticles 的物理化学的性质的新奇 nanoparticles 和描述的开发。然而在这些基于纳米技术的药交货系统的设计和评估,交付的药的药理学并且(patho-) 主人的生理学收到了更少的注意。在这评论,我们讨论集成于使纳米技术能的药交货系统和治疗的设计的重要药理学机制,生理的特征,和病理学的因素。第一手的例子被举由利用 1 为癌症治疗说明如此的综合设计策略的原则和优点)到克服的multidrug抵抗的癌症的药药和 drug-nanomaterial 联合的细胞内部的 synergistic 相互作用, 2 )循环系统到的血流动方向为肺转移最大化药交货到肿瘤 neovasculature 和房间 overexpressing integrin 受体, 3 )装饰 nanocarriers 和 t 的内长的脂蛋白关于在糖尿病管理的申请,一个使纳米技术能的靠近环的胰岛素交货系统被设计在生理地相关的时间规模和葡萄糖层次提供动态胰岛素版本。和另外的研究结果,这些例子建议药理学的相互影响的那利用,(patho-) 生理学和纳米技术是一条灵巧的途径与高效率和翻译潜力开发创新的药交货系统和治疗。 | Rui Xue ZHANG Jason LI Tian ZHANG Mohammad A AMINI Chunsheng HE Brian LU Taksim AHMED HoYin LIP Andrew M RAUTH Xiao Yu WU | 2018 | Acta Pharmacologica Sinica2018，39，5： | 3 |
| 3 | Development of an educational cartoon to prevent worm infections in Chinese schoolchildren显示文摘Background:With more than two billion people infected worldwide,soil-transmitted helminths(STH)are the most widespread infections.To date,STH control efforts rely predominantly on recurrent mass drug administration(MDA),which does not prevent reinfection.Additional public health measures including novel health educational tools are required for more sustained integrated control of STH.We describe the development of an educational cartoon video(The Magic Glasses)targeting STH infections in Chinese schoolchildren and its pilot testing in China.We applied an extensive community-based mixed methods approach involving input from the target group of 9–10 year old schoolchildren and key informants,such as teachers,doctors and parents,in order to identify potential STH infection risks in the study area and to formulate key messages for the cartoon.The development of the educational cartoon included three major steps:formative research,production,and pilot testing and revision.Results:We found that most adults and approximately 50%of the schoolchildren were aware of roundworm(Ascaris)infection,but knowledge of transmission,prevention and treatment of STH was poor.Observations in the study area showed that unhygienic food practices,such as eating raw and unwashed fruit or playing in vegetable gardens previously fertilised with human faeces,posed major STH infection risks.Conclusions:It was crucial to assess the intellectual,emotional,social and cultural background of the target population prior to video production in order to integrate the key messages of the cartoon into everyday situations.Overall,our strategy for the development of the cartoon and its incorporation into a health education package proved successful,and we provide a summary of recommendations for the development of future educational videos based on our experiences in China. | Franziska A Bieri Li-Ping Yuan Yue-Sheng Li Yong-Kang He Andrew Bedford Robert S Li Feng-Ying Guo Sheng-Ming Li Gail M Williams Donald P McManus Giovanna Raso Darren J Gray | 2013 | Infectious Diseases of Poverty2013，2，1： | 2 |
| 4 | High pressure synthesis of cu- bic boron nitride from Si - HBN system显示文摘 | D W He M A Kaishi T Tanaka | 2001 | Diamond and Related Materials2001，，10： | 1 |
| 5 | Synthesis of α-Bromo-4-Substituted-Phenone显示文摘 | HU A X HE L M SHI W G | 2004 | Fine Chemicals2004，21，： | 1 |
| 6 | AIDA:adaptive application independent data aggregation in wireless sensor networks显示文摘 | Tian He Brian M Blum John A Stankovic | 2002 | ACM Transactions on Embedded Computing Systems2002，3，2： | 1 |
| 7 | Active fluid flow in the Eugene Island Area, offshore Louisiana 显示文摘 | Anderson R N He Wei Hobart M A | 1991 | Geophysics1991，10，4： | 1 |
| 8 | Risk factors for pediattic ventriculoperitoneal shunt infection and predictors of infectious pathogens 显示文摘 | McGirt M J Zaas A Fuchs HE | 2003 | Clin Infect Dis2003，36，7： | 1 |
| 9 | Growth hormone receptor is a target for presenilin-dependent gam- ma-secretase cleavage 显示文摘 | Cowan J W Wang X D Guan R He K Jiang J Baumann G Black R A Wolfe M S Frank S J | 2005 | J Biol Chem2005，280，19： | 1 |
| 10 | Effects of morphology on the cohesion of compressed thin films显示文摘 | Evans A G Hutchinson J W | 1998 | Mater Sci Eng1998，245，： | 1 |
| 11 | A Fluorescent Sensor with High Selectivity and Sensitivity for Potassium in Water显示文摘 | He H Mortellaro M A Leiner M J P | 2003 | J Am Chem Soc2003，125，： | 1 |
| 12 | AIDA: Adaptive application independent data aggregation in wireless sensor networks显示文摘 | He T Blum B M Stankovic J A | 2004 | ACM Transaction on Embedded Computing System2004，3，2： | 1 |
| 13 | Increased cadmium and lead uptake of a cadmium hyperaccumulator tomato by cadmium-resistant bacteria 显示文摘 | HE L Y CHEN A J REN G D ZHANG Y F QIAN M SHENG X F | 2009 | Ecotoxicology and Environmental Safety2009，72，： | 1 |
| 14 | Gefitinib enhances the radiosensitivity of nasopharyngeal carcinoma cell line CNE2in vitro显示文摘 | HE B F SUN A M HUANG B Y | 2011 | Nan Fang Yi Ke Da Xue Xue Bao2011，31，： | 1 |
| 15 | Structure of graphiteoxide revisited显示文摘 | LERF A HE H FORSTER M | 1998 | Journal of Physical Chemistry B1998，102，23： | 1 |
| 16 | Simulation of stresses and delamination in a plasma-sprayed thermal barrier system upon thermal cycling显示文摘 | HE M Y HUTCHINSON J W EVANS A G | 2003 | Materials Science and Engineering A2003，345，12： | 1 |
| 17 | Inhibitory mechanisms of tea polyphenols on the ultraviolet B-activated phosphatidylinositol 3-kinase-dependent pathway 显示文摘 | Nomura M Kaji A He Z | 2001 | J Biol Chem2001，276，46： | 1 |
| 18 | A scaled boundary finite element method for cyclically sym- metric two-dimensional elastic analysis显示文摘 | He Y Q Yang H T Xu M Deeks A J | 2013 | Computers Structures2013，120，： | 1 |
| 19 | Methylation levels at IGF2 and GNAS DMRs in infants born to preeclamptic pregnancies 显示文摘 | He J Zhang A Fang M | 2013 | BMC Genomics2013，14，： | 1 |
| 20 | On the availability of a k-out-of-N system given limited spares and re- pair capacity under a condition based maintenance strategy 显示文摘 | DE SMIDT-DESTOMBES K S VAN DER HE/J- DEN M C VAN HARTEN A | 2004 | Reliablity Engineering and System Safety2004，83，： | 1 |
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