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| 1 | Role of self-expanding metal stents in the management ofvariceal haemorrhage:Hype or hope?显示文摘Despite the advances of medical,endoscopic and radiological therapy over recent years the mortality rates of acute variceal haemorrhage are still 16%-20% and the medium term outcome has not improved in the last 25 years. Early transjugular intrahepatic portosystemic shunt has proved to be an effective therapy for selected groups of patients with a high risk of re-bleeding and moderate liver disease. However,there is an unmet need for a therapy that can be applied in patients with a high risk of re-bleeding and advanced liver disease either as definitive therapy or as a bridge to permanent therapy. Selfexpanding metal stents can be placed without the need for endoscopic or fluoroscopic control and,once in place,will provide effective haemostasis and allow a route for oral fluids and nutrition. They can remain in place whilst liver function recovers and secondary prophylaxis is initiated. We review the results of 6 case series including a total of 83 patients and the first randomised controlled trial of self-expanding metal stents vs balloon tamponade(BT) in the management of refractory variceal haemorrhage. We report that self-expanding metal stents provide effective haemostasis and perform better than BT in refractory bleeding,where they are associated with fewer complications. Whilst the most effective place for self-expanding metal stents in the management algorithm needs to be determined by further randomised controlled trials,currently they provide an effective alternative to BT in selected patients. | Brian J Hogan James P O’Beirne | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，1： | 5 |
| 2 | 食管扩张——一种胃食管反流触发机制显示文摘目的 :明确食管扩张时下食管括约肌发生松弛状态下胃食管反流的发生率。方法 :12例健康志愿者在餐前和餐后同时检测食管压力和 pH ,食管扩张是通过快速和缓慢的气体注射诱发。 结果 :引起完全的下食管扩约肌松弛的气体阈值量平均为 (11 0± 1 0 )ml。只有极少的松弛伴有继发蠕动。快速注气下食管括约肌的松弛时间为(13.0± 1.5 )s;慢速注射时食管括约肌的松弛时间是 (16 0± 2 0 )s。由快速阈值量气体注射引起LES松弛并伴有胃食管反流率 ,在餐后为 (2 2± 6 ) % ;缓慢注射时为 (2 3± 10 ) %。对于快速食管扩张 ,单独的下食管括约肌松弛伴随反流的百分比显著高于伴有继发蠕动的下食管括约肌松弛时出现的胃食管反流情况。结论 :(1)胃食管反流可以发生在由食管扩张引起的下食管括约肌松弛期内 ;(2 )食管扩张可以引起不伴随继发蠕动的单纯下食管括约肌松弛 ;(3)单纯下食管括约肌松弛时的胃食管反流发生率显著高于伴有继发蠕动的情况。 | 谢鹏雁 Eytan Bardan Junlong Ren Walter J Hogan Reza Shaker | 2000 | 北京医科大学学报2000，32，2： | 5 |
| 3 | Overview of the progress on haploidentical hematopoietic transplantation显示文摘Allogeneic hematopoietic stem cell transplant(HSCT) remains the only potentially curative option for variety of hematologic disorders. Lack of a suitable fully HLAmatched donor limits this option for many patients. Without a suitable related or unrelated HLA-matched donor,umbilical cord blood and haploidentical family members provide a potential source of stem cells. Timely donor availability makes haploidentical donors an attractive alternative donor source. Initial attempts at haploidentical HSCT was associated with significantly increased mortality owing to high rates of graft rejection and severe graftversus-host disease caused by major donor-recipient HLAdisparity. However, over the past decade, outcomes of haploidentical HSCT have improved significantly. Here, we review the advantages and challenges of haploidentical transplantation. We also discuss new developments to attempt to overcome the challenges to a successful haploidentical transplantation. | Nosha Farhadfar William J Hogan | 2016 | World Journal of Transplantation2016，6，4： | 2 |
| 4 | Cubic AgPb, SbTez+,, : bulk thermoelectric materials with high figure of merit 显示文摘 | Hsu K F Loo S Guo F Chen W Dyck J S Uher C Hogan T Polychroniadis E K Kanatzidis M G | 2004 | Science2004，303，： | 1 |
| 5 | Transcriptional regulation by calcium, ealeineurin and NFAT显示文摘 | Hogan PG Chen L Nardone J | 2003 | Genes Dev2003，17，： | 1 |
| 6 | Genetically null mice reveal a central role for epidermal growth factor receptor in the differentiation of the hair follicle and normal hair development显示文摘 | Hansen L A Alexander N Hogan M E Sundberg J P Dlugosz A Threadgill D W Magnuson T Yuspa S H | | 0，，06： | 1 |
| 7 | Exercise holds immediate benefits for affect and cognition in younger and older adults显示文摘 | HOGAN C L MATA J CARSTENSEN L L | 2013 | Psycholo- gy and aging2013，28，2： | 1 |
| 8 | Hybrid channel conflict: Causes and effects on channel performance 显示文摘 | Webb K L Hogan J E | 2002 | Journal of Business & IndustrialMarketing2002，17，5： | 1 |
| 9 | Should mycophenolate mofetil replace cyclophosphamide as first-line therapy for se- vere lupus nephritis? 显示文摘 | Hogan J Schwenk M Radhakrishnan J | 2012 | Kidney Int2012，，： | 1 |
| 10 | Synthesis properties and catalytic behaviour of zeolite Nu-10 显示文摘 | HOGAN P J WHITTAM T V BIRTILL J | 1984 | Zeolites1984，4，3： | 1 |
| 11 | Exclusion of unstable cervical spine injury in obtunded patients with blunt trauma:is MR imaging needed when multi-detector row CT findings are normal显示文摘 | Mirvis SE Shanmuganathan K | 2005 | Radiology2005，237，1： | 1 |
| 12 | New 4 - axis VMC Range from Cincinnati 显示文摘 | HOGAN Brian J | 2007 | Metalworking Production2007，，3： | 1 |
| 13 | Memory-related EEG power and coherence reduction in mild Alzheimer's disease 显示文摘 | Hogan MJ Swanwick GRJ Kaiser J | 2003 | Int J Psychophysiol2003，49，： | 1 |
| 14 | Resistance to diet-induced obesity: food intake, pancreatic sympathetic tone, and insulin 显示文摘 | Levin BE Triscari J Hogan S | 1987 | Am J Physiol1987，252，32： | 1 |
| 15 | Maternal mortality for 181 countries, 1980-2008: a systematic analysis of progress towards Millennium Development Goal 5 显示文摘 | Hogan MC Foreman K J Naghavi M | 2010 | Lancet2010，375，9726： | 1 |
| 16 | Intraluminal esophageal manometry:an analysis of variables affecting recording fidelity of peristaltic pressures显示文摘 | Stef J J Dodds W J Hogan W J | | 0，，： | 1 |
| 17 | Relapse-specific mutations in NT5C2 in childhood acute lymphoblastic leukemia显示文摘 | Meyer JA Wang J Hogan LE | 2013 | Nat Genet2013，45，3： | 1 |
| 18 | The Effect of Human Resource Investment in Internal Control on the Disclosure of In- ternal Control Weaknesses 显示文摘 | Choi J H Choi S H Hogan C E Lee J | 2013 | Auditing: A Journal of Practice &Theory2013，32，4： | 1 |
| 19 | Endoscopic sphincterotomy:follow-up evaluation of effects on the sphincter of Oddi Gastroenterology显示文摘 | Toouli J Hogan WJ | 1984 | ? 1984 Oct1984，87，4： | 1 |
| 20 | An improved murine model of asthma : selective airway inflammation, epithelial lesions and increased methacholine responsiveness following chronic exposure to aerosolised allergen 显示文摘 | Temelkovski J Hogan SP Shepherd DP Foster PS Kumar RK | 1998 | Thorax1998，53，10： | 1 |
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