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| 1 | 急性脊髓损伤患者治疗的临床操作指南:关于MRI基线在临床治疗决策与结果预测中作用的几点建议(英文)显示文摘The objective of this guideline is to outline the role of magnetic resonance imaging(MRI) in clinical decision making and outcome prediction in patients with traumatic spinal cord injury(SCI).Methods A systematic review of the literature was conducted to address key questions related to the use of MRI in patients with traumatic SCI.This review focused on longitudinal studies that controlled for baseline neurologic status.A multidisciplinary Guideline Development Group(GDG) used this information,their clinical expertise,and patient input to develop recommendations on the use of MRI for SCI patients.Based on GRADE(Grading of Recommendation,Assessment,Development and Evaluation),a strong recommendation is worded as ' we recommend,' whereas a weaker recommendation is indicated by 'we suggest.' Results Based on the limited available evidence and the clinical expertise of the GDG,our recommendations were:(1) 'We suggest that MRI be performed in adult patients with acute SCI prior to surgical intervention,when feasible,to facilitate improved clinical decision-making'(quality of evidence,very low) and(2) 'We suggest that MRI should be performed in adult patients in the acute period following SCI,before or after surgical intervention,to improve prediction of neurologic outcome '(quality of evidence,low).Conclusions These guidelines should be implemented into clinical practice to improve outcomes and prognostication for patients with SCI. | Fehlings MG Martin AR Tetreault LA Aarabi B Anderson P Arnold PM Brodke D Burns AS Chiba K Dettori JR Furlan JC Hawryluk G Holly LT Howley S Jeji T Kalsi-Ryan S Kotter M Kurpad S Kwon BK Marino RJ Massicotte E Merli G Middleton JW Nakashima H Nagoshi N Palmieri K Singh A Skelly AC Tsai EC Vaccaro A Wilson JR Yee A Harrop JS | 2017 | 中华神经外科疾病研究杂志2017，16，6： | 8 |
| 2 | Role of stem cell therapies in treating chronic wounds:A systematic review显示文摘BACKGROUND The impairment of cutaneous wound healing results in chronic,non-healing wounds that are caused by altered wound environment oxygenation,tissue injury,and permissive microbial growth.Current modalities for the treatment of these wounds inadequately address the complex changes involved in chronic wound pathogenesis.Consequently,stem cell therapies have emerged as a potential therapeutic modality to promote cutaneous regeneration through trophic and paracrine activity.AIM To investigate current literature regarding use of stem cell therapies for the clinical treatment of chronic,non-healing wounds.METHODS PubMed,EMBASE,Cochrane Library,Web of Science,and Scopus were queried with combinations of the search terms“mesenchymal stem cells,”“adult stem cells,”“embryonic stem cells,”“erythroid precursor cells,”“stem cell therapies,”and“chronic wounds”in order to find relevant articles published between the years of 2000 and 2019 to review a 20-year experience.Reference lists from the articles were reviewed to identify additional pertinent articles.Retrieved manuscripts(reviews,case reports/series,retrospective/prospective studies,and clinical trials)were evaluated by the authors for their depiction of clinical stem cell therapy use.Data were extracted from the articles using a standardized collection tool.RESULTS A total of 43 articles describing the use of stem cell therapies for the treatment of chronic wounds were included in this review.While stem cell therapies have been explored in in vitro and in vivo applications in the past,recent efforts are geared towards assessing their clinical role.A review of the literature revealed that adipose-derived stem cells,bone marrow-derived stem cells,bone marrowderived mononuclear cells,epidermally-derived mesenchymal stem cells,fibroblast stem cells,keratinocyte stem cells,placental mesenchymal stem cells,and umbilical cord mesenchymal stem cells have all been employed in the treatment of chronic wounds of various etiologies.Most recently,embryonic stem cells have emerged as a novel stem cell therapy with the capacity for multifaceted germ cell layer differentiation.With the capacity for self-renewal and differentiation,stem cells can enrich existing cell populations in chronic wounds in order to overcome barriers impeding the progression of wound healing.Further,stem cell therapies can be utilized to augment cell engraftment,signaling and activity,and resultant patient outcomes.CONCLUSION Assessing observed clinical outcomes,potential for stem cell use,and relevant therapeutic challenges allows wound care stakeholders to make informed decisions regarding optimal treatment approaches for their patients’chronic wounds. | Anjali C Raghuram Roy P Yu Andrea Y Lo Cynthia J Sung Melissa Bircan Holly J Thompson Alex K Wong | 2020 | World Journal of Stem Cells2020，12，7： | 5 |
| 3 | Global epidemiology of hepatitis B and hepatitis C in people who inject drugs: results of systematic reviews显示文摘 | Paul K Nelson Bradley M Mathers Benjamin Cowie Holly Hagan Don Des Jarlais Danielle Horyniak Louisa Degenhardt | 2011 | The Lancet . 2011 (9791)2011，，： | 2 |
| 4 | Postoperative PINP in serum reflects metastatic potential and poor survival in node-positive breast cancer显示文摘 | Jukkola A Bloigu R Holli K | 2001 | Anticancer Res2001，21，4： | 1 |
| 5 | Contrast magnetic resonance imaging in the assessment of myocardial in patients with stable coronary artery disease and left ventricular dysfunction显示文摘 | Ranani K Judd RM Holly TA | 1998 | Circulation1998，98，： | 1 |
| 6 | Adjuvant trials of toremifene vs tamoxifen:the European experience显示文摘 | Holli K | 1998 | Oncology(Huntingt)1998，12，35： | 1 |
| 7 | Lumpectomy with or without postoperative radiotherapy for breast cancer with favorable prognostic features : results of a randomized study 显示文摘 | Holli K Saaristo R Isola J | 2001 | Br J Cancer2001，84，2： | 1 |
| 8 | A single ended 6T SRAM cell design for ultra-low-voltage applications 显示文摘 | Jawar Singh Dhiraj K Pradhan Simon Hollis | 2008 | ICICE Electronic Express2008，5，18： | 1 |
| 9 | X-33 aerodynamic computations and comparisons with windtunnel data显示文摘 | Hollis B R Thompson R A Murphy K J etal | 2001 | Journal of Spacecraft and Rockets2001，38，5： | 1 |
| 10 | CA15-3 in the follow-up of localised breast cancer: a prospective study 显示文摘 | Kokko R Holli K Hakama M | 2002 | Eur J Cancer2002，38，9： | 1 |
| 11 | Promotion of megakar yocyte progenitor expansion and differentiation by the c-Mpl ligand thrombopoietin显示文摘 | Kaushansky K Lok S Holly RD | 1994 | Nature1994，369，6481： | 1 |
| 12 | Minimally invasive lumbar fusion 显示文摘 | Foley K T Holly L T Schwender J D | 2003 | Spine2003，15，： | 1 |
| 13 | Using Publications Counts to Measure an Institution's Research Productivity显示文摘 | TOUTKOUSHIAN R K PORTER S R DANIELSON C HOLLIS P R | 2003 | Research in Higher Education2003，44，2： | 1 |
| 14 | Do practice nurses have theknowledge to provide diabetes self - management education 显示文摘 | HOLLIS M GLAISTER K LAPSLEY JA | 2014 | Contemp Nurse2014，46，2： | 1 |
| 15 | Risk adjustment in Switzerland显示文摘 | Beck K Spycher S Holly A | 2003 | Health Policy2003，65，1： | 1 |
| 16 | Promotion of megakaryocyte progenitor expansion and differentiation by the c-MPL ligand thrombopoietin 显示文摘 | Kaushansky K Lok S Holly R D | 1994 | Nature1994，369，6481： | 1 |
| 17 | Radiological pulmonary findings after breast cancer irradiation: a prospective study显示文摘 | Jarvenpaa R Holli K Pitkanen M | 2006 | Acta Oncol2006，45，1： | 1 |
| 18 | Low biologic aggressiveness in breast cancer in women using hormone replacement therapy显示文摘 | Isola J Cuzick J | 1998 | J Clin Oncol1998，16，9： | 1 |
| 19 | Residential water source and the risk of childhood brain tumors显示文摘 | Mueller BA Newton K Holly EA | 2001 | Environ Health Perspect2001，109，6： | 1 |
| 20 | Insulin-like growth factor-binding protein-2 promotes prostate cancer cell growth via IGF-dependent or -independent mechanisms and reduces the efficacy of docetaxel显示文摘 | Uzoh C C Holly J M Biernacka K M Persad R A Bahl A Gillatt D | 2011 | Br J Cancer2011，104，： | 1 |
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