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| 1 | Nutrition in chronic pancreatitis显示文摘The pancreas is a major player in nutrient digestion.In chronic pancreatitis both exocrine and endocrine insufficiency may develop leading to malnutrition over time.Maldigestion is often a late complication of chronic pancreatic and depends on the severity of the underlying disease.The severity of malnutrition is correlated with two major factors:(1)malabsorption and depletion of nutrients(e.g.,alcoholism and pain)causes impaired nutritional status;and(2)increased metabolic activity due to the severity of the disease.Nutritional deficiencies negatively affect outcome if they are not treated.Nutritional assessment and the clinical severity of the disease are important for planning any nutritional intervention.Good nutritional practice includes screening to identify patients at risk,followed by a thoroughly nutritional assessment and nutrition plan for risk patients.Treatment should be multidisciplinary and the mainstay of treatment is abstinence from alcohol,pain treatment,dietary modifications and pancreatic enzyme supplementation.To achieve energy-end protein requirements,oral supplementation might be beneficial.Enteral nutrition may be used when patients do not have sufficient calorie intake as in pylero-duodenalstenosis,inflammation or prior to surgery and can be necessary if weight loss continues.Parenteral nutrition is very seldom used in patients with chronic pancreatitis and should only be used in case of GI-tract obstruction or as a supplement to enteral nutrition. | Henrik Hφjgaard Rasmussen φivind Irtun Sφren Schou Olesen Asbjφrn Mohr Drewes Mette Holst | 2013 | World Journal of Gastroenterology2013，19，42： | 4 |
| 2 | Grp78 is involved in retention of mutant low density lipoprotein receptor protein in the endoplasmic reticulum显示文摘 | Jrgensen M M Jensen O N Holst H U | 2000 | J Biol Chem2000，275，33： | 1 |
| 3 | Temporal and spatial dynamics of planktonic rotifers in the Elbe Estuary during spring显示文摘 | Holst H Zimmermann H Kausch H | 1998 | Estuarine Coastal and Shelf Science1998，47，3： | 1 |
| 4 | Four weeks of near-normalisation of blood glucose improves the insulin response to glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes显示文摘 | P. V. H?jberg T. Vilsb?ll R. Rab?l F. K. Knop M. Bache T. Krarup J. J. Holst S. Madsbad | 2009 | Diabetologia2009，，2： | 1 |
| 5 | Elastase-producing Pseudomonas aeruginosa degrade plasma proteins and extracelluar products of human skin and fibroblasts, and inhibit fibroblast growth显示文摘 | Schmidtchen A Holst E Tapper H | 2003 | Microbiol Pathogenesis2003，34，： | 1 |
| 6 | Zona pellucida binding assay-A method for evaluation of canine spermatosoa显示文摘 | Strom Holst B Larsson B Rodriquez-Martinez H | 2001 | J Reprod Fertil Suppl2001，57，： | 1 |
| 7 | Effects of glucagon-like peptide-l on islet function and insulin sensitivity in noninsulin-dependent diabetes mellitus 显示文摘 | Ahren B Larsson H Holst JJ | 1997 | J Clin Endocrinol Metab1997，82，2： | 1 |
| 8 | Controlled subtotal evacuation of intracerebral haematomas by stereotactic technique显示文摘 | Backlund EO van Holst H | 1978 | Surg Neurol1978，9，： | 1 |
| 9 | Molecular cloning, genomic organization, and expression of a testicular isoform of hormone-sensitive lipase 显示文摘 | Holst L S Langin D Mulder H | 1996 | Genomies1996，35，3： | 1 |
| 10 | Cervical length in women in preterm labor with intact membranes: relationship to intra-amniotic inflammation/microbial invasion, cervical inflammation and preterm delivery 显示文摘 | Holst RM Jacobsson B Hagberg H | 2006 | Ultrasound Obstet Gynecol2006，28，6： | 1 |
| 11 | Controlled subtotal evacuation of intracerebral haematomas by stereotactic technique显示文摘 | Backlund EO van Holst H | | 0，，02： | 1 |
| 12 | Effects of giving water 25-450 ml with oral diazepam premedication 1-2 h before operation显示文摘 | SOREIDE E HOLST L H REITE K | 1993 | Br J Anaesth1993，71，： | 1 |
| 13 | Scalable signaling mediated by T cell antigen receptor-CD3 ITAMs ensures effective negative selection and prevents autoimmunity显示文摘 | HOLST J WANG H EDER K D | 2008 | NatImmunol2008，9，6： | 1 |
| 14 | The validation and assess- ment of machine learning: a game of prediction from high-dimen- sional data显示文摘 | Pers T H Mbrechtsen A Holst C | 2009 | PLoS ONE2009，4，8： | 1 |
| 15 | Hormone-sensitive lipase,the rate-limiting enzyme in triglyceride hydrolysis,is expressed and active in β-cells显示文摘 | Mulder H Holst LS Svensson H | 1999 | Diadetes1999，48，1： | 1 |
| 16 | Optimal operation of coproduction with storage显示文摘 | H Zhao J Holst L Arvastson | 1998 | Energy1998，23，： | 1 |
| 17 | Prenatal determinantsof neonatal lung function in high-risk newboTns 显示文摘 | Bisgaard H Loland L Holst K K | 2009 | J Aller ClinImmunol2009，123，3： | 1 |
| 18 | Increased circulating leptin in alcoholic cirrhosis :Relation to release and disposal 显示文摘 | HENRIKSEN J H HOLST J J MOLLER S | 1999 | Hepatology1999，29，： | 1 |
| 19 | Nerve growth factor affects 11C-nicoding binding,blood flow,EEG and verbal episodic memory in an Alzheimer patient显示文摘 | Olson L Nordberg A von Holst H | | 0，，： | 1 |
| 20 | Bacteria derived particles as adjuvants for non-replicating nasal vaccines显示文摘 | Haneberg B Berstad A K H Holst J | 2001 | Adv Drug Deliv Rev2001，51，13： | 1 |
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