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| 1 | Effect of resistance training on non-alcoholic fatty-liver disease a randomized-clinical trial显示文摘AIM:To evaluate the effect of resistance training(RT)on non alcoholic liver disease(NAFLD)patients.METHODS:A randomized clinical trial enrolling NAFLD patients without secondary liver disease(e.g.,without hepatitis B virus,hepatitis C virus or excessive alcohol consumption).Patients were randomly allocated either to RT,three times weekly,for 3 mo or a control arm consisting of home stretching.The RT included leg press,chest press,seated rowing,latissimus pull down etc.with 8-12 repetitions,3 sets for each exercise,for a total duration of 40 min.Hepatic ultrasound,fasting blood tests,anthropometrics and body composition by dual energy X-ray absorptiometry were assessed.At baseline and follow-up,patients filled out a detailed semi-quantitative food frequency questionnaire reporting their habitual nutritional intake.Steatosis was quantified by the hepatorenal-ultrasound index(HRI)representing the ratio between the brightness level of the liver and the right kidney.The HRI has been previously demonstrated to be highly reproducible and was validated against liver biopsy and proton magnetic resonance spectroscopy.RESULTS:Eighty two patients with primary NAFLD were randomized to receive 3 mo of either RT or stretching.After dropout or exclusion from analysis because of protocol violation(weight change>3 kg),thirty three patients in the RT arm and 31 in the stretching arm completed the study per protocol.All baseline characteristics were similar for the two treatment groups with respect to demographics,anthropometrics and body composition,blood tests and liver steatosis on imaging.HRI score was reduced significantly in the RT arm as compared to the stretching arm(-0.25±0.37 vs-0.05±0.28,P=0.017).The RT arm had a significantly higher reduction in total,trunk and android fat with increase in lean body mass.There was no correlation between the reduction in HRI in the RT arm and weight change during the study,but it was positively correlated with the change in trunk fat(r=0.37,P=0.048).The RT arm had a significant reduction in serum ferritin and total cholesterol.There was no significant difference between arms in dietary changes and these did not correlate with HRI change.CONCLUSION:Three months RT improves hepatic fat content accompanied by favorable changes in body composition and ferritin.RT may serve as a complement to treatment of NAFLD. | Shira Zelber-Sagi Assaf Buch Hanny Yeshua Nahum Vaisman Muriel Webb Gil Harari Ofer Kis Naomi Fliss-Isakov Elena Izkhakov Zamir Halpern Erwin Santo Ran Oren Oren Shibolet | 2014 | World Journal of Gastroenterology2014，20，15： | 17 |
| 2 | The evolution of female sex pheromones显示文摘 | Ally R. HARARI Hadass STEINITZ | 2013 | Current Zoology2013，59，4： | 5 |
| 3 | Hsp90 increases LIM kinase activity by promoting its homo-dimerization 显示文摘 | Li R Soosairajah J Harari D | 2006 | FASEB J2006，20，8： | 1 |
| 4 | Neurocognitive basis of impaired empathy in schizophrenia显示文摘 | Shamay-Tsoory SG Shur S Harari H | 2007 | Neuropsychology2007，21，4： | 1 |
| 5 | Boolean operations on graphs显示文摘 | Harary F Wilcox G W | 1967 | Math Scand1967，20，： | 1 |
| 6 | Modulation of radiation response after epidermal growth factor receptor blockade in squamous cell carcinomas: inhibition of damage repair, cell cycle kinetics, and tumor angiogenesis显示文摘 | Huang SM Harari PM | 2000 | Clin Cancer Res2000，6，6： | 1 |
| 7 | Criterion for unanimity in French's theory of social power显示文摘 | Harary F A | 1959 | Studies in Social Power1959，2，1： | 1 |
| 8 | Dominant TNF-α+Mycobacterium tuberculosis-specific CD4+T cell responses discriminate between latent infection and active disease显示文摘 | Harari A Rozot V Bellutti Enders F | 2011 | Nat Med2011，17，3： | 1 |
| 9 | Radiotherapy plus cetux imab for squamous cell carcinoma of head and neck显示文摘 | Bonner J A Harari P M Giralt | 2006 | N Engl J Med2006，354，6： | 1 |
| 10 | Molecular inhibition of anglogenesis and metastatic potential in human squamous cell carcinomas after epidermal growth factor receptor blockade 显示文摘 | Huang SM Li J Harari PM | 2002 | Mol Cancer Ther2002，1，： | 1 |
| 11 | Radiotherapy plus cetuximab for squamous cell carcinoma of the head and neck显示文摘 | Harari PM Giralt J et a1 | 2006 | New Engl J Med2006，354，6： | 1 |
| 12 | Modification of hydrogen-passivated silicon by a scanning tunneling microscope operating in air显示文摘 | Sehneir J Harary H H | 1990 | Appl Phys Lett1990，56，20： | 1 |
| 13 | Modulation of radiation response after epidermal growth factor receptor blockade in squamans cell carcinomas:inhibition of damage repair,cell cycle kinetics,and tumor angiogenesis显示文摘 | Huang SM Harari PM | 2000 | Clin Cancer2000，6，： | 1 |
| 14 | The association of resting heart rate with cardiovascular, cancer and all-causemortality: eight year follow-up of 3527 male Israeli employ- ees(the CORDISS Study) 显示文摘 | Kristal-Boneh E Silber H Harari G | 2000 | Eur Heart J2000，21，2： | 1 |
| 15 | Digraphs with Real and Gaussian Spectra显示文摘 | Esser F Harary F | 1980 | Discrete Applied Mathematics1980，，2： | 1 |
| 16 | Covering and packing in gaphs Ⅲ (Cyclic and acyclic invariants)显示文摘 | Akiyama J Exoo G Harary F | 1980 | Math Slovaca1980，30，： | 1 |
| 17 | Modulation of radiation response after epidermal growth factor receptor blockade in squamous cell carcinomas: Inhibition of damage repair, cell cycle kinetics, and tumor angiogenesis显示文摘 | Huang SM Harari PM | 2000 | Clin Cancer Res2000，6，6： | 1 |
| 18 | Radio labelings of graphs显示文摘 | CHARTRAND G ERWIN D HARARY F | 2001 | Bull Inst Combin AppL2001，33，： | 1 |
| 19 | Malignant pheochromocytoma: a review 显示文摘 | Harari A Inabnet WB 3rd | 2011 | Am J Surg2011，201，5： | 1 |
| 20 | The effect of mechanical force on mRNA levels of collagenase,colla- gen type I,and tissue inhibitors of metalloproteinases in gingivae of dogs显示文摘 | Redlich M Reichenberg E Harari D | 2001 | Journal of Dental Research2001，80，12： | 1 |
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