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| 1 | 器官移植受体发生EBV阳性的皮肤黏膜溃疡:一种局限性惰性移植后淋巴组织增殖性疾病显示文摘Epstein-Barr 病毒( EBV )阳性的皮肤黏膜溃疡( EBV MCU)是在老人或医源性免疫受损患者中发生的一种B细胞淋巴组织增殖性疾病,尚未见发生于实体器官移植受者的报道。作者在70例EBV阳性移植后淋巴组织增殖性疾病( PTLD)患者中发现7例EBV阳性MCU。包括5例肾脏、1例心脏和1例肺脏移植,其中男性5例。患者中位年龄61岁,4例发生于口腔黏膜,3例发生于胃肠道。溃疡病变发生前患者接受免疫抑制治疗0.6-13年。溃疡由炎症细胞和多形性或单形性大细胞增生,破坏皮肤黏膜而形成。5例中可见Reed-Sternberg样细胞。所有病例CD20、CD30阳性,原位杂交EBER结果阳性。3例近期患者被诊断为EBV阳性MCU,4例患者前期被诊断为单形性大细胞PTLD(n=3)和多形性 PTLD ( n =1)。所有患者血液 EBV DNA 均阴性(〈1000拷贝数/ml),而在诊断或随访的44例移植患者中有35例发生系统性 PTLD ( P 〈0.001)。所有 EBV 阳性MCU患者通过减少免疫抑制剂用量(7/7),调整免疫抑制剂用量(2/7),和联用利妥昔单抗(3/7)等使皮损得到治愈。目前5例存活:其中4例身体健康,1例在等待肾移植手术;另2例分别在EBV阳性MCU治愈后的3年和5年死亡。未发现EBV阳性MCU复发或其他PTLD。 | Hart M Thakral B Yohe S 胡舜摘 余英豪 | 2014 | 临床与实验病理学杂志2014，30，12： | 5 |
| 2 | Voltammetric behavior of ascorbic acid at a graphite-epoxy composite electrode chemically modified with cobalt phthalocyanine and its amperometric determination in multivitamin preparations显示文摘 | Wring S A Hart J P Birch B J | 1990 | Anal Chim Acta1990，229，： | 2 |
| 3 | 13C andl5N natural abundance of the soil microbial biomass显示文摘 | Dijkstra P Ishizu A Doucett R Hart S C Schwartz E Menyailo O V Hungate B A | 2006 | Soil Biology & Biochemistry2006，38，： | 1 |
| 4 | Synthesis ofdimethylcarbonate by vapor phase oxidative carbonylation of methanol over Cu-based catalysts显示文摘 | Hart M S Lee B G Ahn B S | 2001 | Journal of Molecular Catalysis2001，170，1： | 1 |
| 5 | Do Corporate Global Environmental Standards Create or Destroy Market Value? 显示文摘 | Dowell G Hart S L Yeung B | 2000 | Management Science2000，46，8： | 1 |
| 6 | An overview of polylactides as packaging materials显示文摘 | Auras R Harte B Selke S | 2004 | Macromolecular Bioscience2004，4，9： | 1 |
| 7 | Three-dimensional seismic based defini tion of fault-related porosity development:Trenton Black River interval,Saybrook, Ohio 显示文摘 | Sagan J A Hart B S | 2006 | AAPG Bulletin2006，90，11： | 1 |
| 8 | Long-term consequences of topsoil mining on select biological and physical characteristics of two New Zealand loessial soils under grazed pasture显示文摘 | HART P B S AUGUST J A WEST A W | 1989 | Land Degrnd Rehab1989，1，1： | 1 |
| 9 | Analysis of ginsenoside composition of woods-grown ginseng roots 显示文摘 | Hart S T Shin C Yang B W | 2007 | Food Sci Biotechnol2007，16，2： | 1 |
| 10 | Channel detection in 3D seismic data using sweetness 显示文摘 | Hart B S | 2008 | AAPG Bulletin2008，92，6： | 1 |
| 11 | CO2 uptakeby a soil microcosm显示文摘 | HART K OPPENHEIMER S F1MORAN B W | 2013 | Soil Biology & Biochemistry2013，57，： | 1 |
| 12 | An overview of polylactides as packaging materials 显示文摘 | AURAS R HARTE B SEOIE S | 2004 | Macromol Biosci2004，，4： | 1 |
| 13 | Long-term consequences of topsoil mining on select biological and physical characteristics of two New Zealand loessial soils under grazed pasture显示文摘 | HART P B S AUGUST J A WEST A W | 1989 | Land DegradRehab1989，1，： | 1 |
| 14 | Porphyrin sensitized solar cells : effect of carboxyl anchor group orientation on the cell performance 显示文摘 | Hart A S KC C B Gobeze H B | 2013 | ACSApplMater Interfaces2013，5，11： | 1 |
| 15 | The nitrogen cycle in the Broadbalk wheat experiment: 15N-labelled fertilizer residues in the soil and in the soil microbial biomass显示文摘 | Shen S M Hart B S Powlson D S | 1989 | Soil Biology and Biochemistry1989，21，4： | 1 |
| 16 | Ischemia - reperfusion decreases protein phosphorylation and p38 mitogen - activated protein kinase phosphorylation in rat lung transplants 显示文摘 | Sakiyama S dePerrot M Hart B Wadded TK Keshavjee S Liu M | 2003 | J Heart Lung Transplantation2003，22，： | 1 |
| 17 | Assessment of an immature platelet fraction (IPF) in peripheral thromhocytopenia显示文摘 | Carol B Kunka S Hart D | 2004 | British Journal of Haematology2004，126，： | 1 |
| 18 | Simulation technology for health care professional skills training and assessment显示文摘 | Issenberg S B McGaghie W C Hart I R | | 0，，09： | 1 |
| 19 | Apocynin, a Low Molecular Oral Treatment for Neurodegenerative Disease 显示文摘 | Hart B A Copray S Philippens I | 2014 | BioMed research international2014，2014，7： | 1 |
| 20 | An Overview of Polylactides as Packaging Materials 显示文摘 | Auras R Harte B Selke S | 2004 | Macromol Biosci2004，4，9： | 1 |
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