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| 1 | Emotion processing in Parkinson's disease: a blood oxygenation level-dependent functional magnetic resonance imaging study显示文摘Parkinson's disease is a neurodegenerative disorder caused by loss of dopamine neurons in the substantia nigra pars compacta. Tremor, rigidity, and bradykinesia are the major symptoms of the disease. These motor impairments are often accompanied by affective and emotional dysfunctions which have been largely studied over the last decade. The aim of this study was to investigate emotional processing organization in the brain of patients with Parkinson's disease and to explore whether there are differences between recognition of different types of emotions in Parkinson's disease. We examined 18 patients with Parkinson's disease(8 men, 10 women) with no history of neurological or psychiatric comorbidities. All these patients underwent identical brain blood oxygenation level-dependent functional magnetic resonance imaging for emotion evaluation. Blood oxygenation level-dependent functional magnetic resonance imaging results revealed that the occipito-temporal cortices, insula, orbitofrontal cortex, basal ganglia, and parietal cortex which are involved in emotion processing, were activated during the functional control. Additionally, positive emotions activate larger volumes of the same anatomical entities than neutral and negative emotions. Results also revealed that Parkinson's disease associated with emotional disorders are increasingly recognized as disabling as classic motor symptoms. These findings help clinical physicians to recognize the emotional dysfunction of patients with Parkinson's disease. | Mohammed Benzagmout Sa?d Boujraf Badreeddine Alami Hassane Ali Amadou Halima El Hamdaoui Amine Bennani Mounir Jaafari Ismail Rammouz Mustapha Maaroufi Rabia Magoul Driss Boussaoud | 2019 | Neural Regeneration Research2019，14，4： | 6 |
| 2 | Concomitant, sequential, and hybrid therapy for H. pylori eradication: a pilot study.显示文摘 | Angelo Zullo Giuseppe Scaccianoce Vincenzo De Francesco Valentina Ruggiero Pasquale D’Ambrosio Luigi Castorini Leonilde Bonfrate Lucy Vannella Cesare Hassan Piero Portincasa | 2013 | Clinics and Research in Hepatology and Gastroenterology2013，，： | 4 |
| 3 | Acid‐suppressive therapy is associated with spontaneous bacterial peritonitis in cirrhotic patients: A meta‐analysis显示文摘 | Abhishek Deshpande Vinay Pasupuleti Priyaleela Thota Chaitanya Pant Sulaiman Mapara Sohaib Hassan David D K Rolston Thomas J Sferra Adrian V Hernandez | 2013 | J Gastroenterol Hepatol2013，，2： | 3 |
| 4 | On hybrid petri Nets显示文摘 | Rene D Hassane A | 2001 | Discrete Event Dynamic Systems2001，11，12： | 2 |
| 5 | 抑郁症的非药物治疗:系统性综述与证据图显示文摘背景抑郁症非药物治疗的疗效比较目前仍然不清楚。方法我们对一些系统性综述作了概述,回顾了随机对照试验(RCT),比较抑郁症非药物治疗的有效性和认知行为治疗(CBT)。对多个电子数据库在2016年2月之前发表的所有文献进行了检索,不限制语言。成对的评阅人进行资料纳入、数据提炼并评估偏倚的风险。在适用的时候进行了荟萃分析。结果我们收录了367项RCT,纳入了约2000名患者,进行了11种治疗,导出17项独立的头对头比较。通过标准化的量表评估,发现CBT、自然疗法、行为干预与躯体活动干预可以降低抑郁的严重程度。然而,这些非药物干预的相对疗效仍然缺乏。这些干预对临床缓解和复发的效果不清楚。CBT的发生率比抗抑郁药物更低。局限性由于证据缺乏一致性、证据不清或偏倚风险高,导致证据的质量只是低到中等,限制了我们研究结果的可信度。结论抑郁症的非药物治疗能减少抑郁症状,在轻度到重度抑郁症患者中,应当合并抗抑郁药物治疗,一同进行。对于非药物治疗的选择,应当根据患者的价值观、偏好、临床和社会因素来与患者共同作出决定。 | Wigdan H Farah Mouaz Alsawas Maria Mainou Fares Alahdab Magdoleen H Farah Ahmed T Ahmed Essa A Mohamed Jehad Almasri Michael R Gionfriddo Ana Castaneda-Guarderas Khaled Mohammed Zhen Wang Noor Asi Craig N Sawchuk Mark D Williams Larry J Prokop M Hassan Murad Annie LeBlanc | 2017 | 英国医学杂志中文版2017，20，11： | 2 |
| 6 | Pioglitazone reduces blood pressure in non-dipping diabetic patients显示文摘 | Negro R Dazzi D Hassan H | 2004 | Minerva Endocrinol2004，29，1： | 1 |
| 7 | Therapeutic considerations in the management of agitated or delirious critically ill patients显示文摘 | HASSAN E FONTAINE D K NEARMAN H S | 1998 | Pharmacotherapy1998，18，： | 1 |
| 8 | A robust LMI- based pitch controller for large wind turbines 显示文摘 | HASSAN H M EISHAFEI A L FARAG W A et d | 2012 | Renewable Energy2012，44，1： | 1 |
| 9 | Development of Glass Fiber Reinforced Plastic Poles for Transmission and Distribu- tion Lines显示文摘 | Ibrahim S Polyzois D Hassan S K | 2000 | Canadian Journal of Civil Engineering2000，27，5： | 1 |
| 10 | Antidiabetic therapies affect risk of pancreatic cancer显示文摘 | Li D Yeung SC Hassan MM | 2009 | Gastroenterology2009，137，2： | 1 |
| 11 | Scan Bist: A multifrequence scan-based BIST method 显示文摘 | Nadeau-Dostie B Burek D Hassan A | 1994 | IEEE Design & Test on Computer1994，11，1： | 1 |
| 12 | Effect of reversal of catheter ports on recirculation: comparison of the PermCath with Tesio Twin Catheter显示文摘 | Hassan H A Frenchie D L Bastani B | 2002 | ASAIO J2002，48，： | 1 |
| 13 | Chemical genomic screening reveals synergism between parthenolide and inhibitors of the PI-3 kinase and mTOR pathways显示文摘 | Hassane D Sen S Minhajuddin M | 2010 | Blood2010，116，26： | 1 |
| 14 | Histopathology and cytopathology of white spot syndrome virus ( WSSV ) in cultured Penaeus monodon from peninsular Malaysia with emphasis on pathogenesis and the mechanism of white spot formation显示文摘 | Wang Y G Hassan M D Shariff M | 1999 | Diseases of Aquatic Organisms1999，39，1： | 1 |
| 15 | Effect of reversal of catheter ports on recirculation:comparison of the Permcath with Tesio Twin Catheter显示文摘 | HASSAN H A FRENCHIE D L BASTANI B | 2002 | ASAIO J2002，48，3： | 1 |
| 16 | Association between hepatitis B virus and pancreatic cancer显示文摘 | Hassan MM Li D El-Deeb AS | | 0，，28： | 1 |
| 17 | Predictorsof short- and long-term outcomes of takotsubo cardiomyopa-thy显示文摘 | Gopalakrishnan M Hassan A Villines D | 2015 | Am J Cardiol2015，116，10： | 1 |
| 18 | Behavioral stress accelerates prostate cancer development in mice 显示文摘 | HASSAN S KARPOVA Y BAIZ D | 2013 | J Clin Invest2013，123，2： | 1 |
| 19 | Immunotoxin therapy of cancer 显示文摘 | Pastan I Hassan R Fitzgerald D J and Kreitman R J | 2006 | Nature Reviews Cancer2006，6，7： | 1 |
| 20 | Discovery of agents that eradicate leukemia stem cells using an in silico screen of public gene expression data显示文摘 | HASSANE D C GUZMAN M L CORBETT C | 2008 | Blood2008，111，12： | 1 |
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