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| 1 | Salivary proteins and microbiota as biomarkers for early childhood caries risk assessment显示文摘Early childhood caries(ECC) is a term used to describe dental caries in children aged 6 years or younger. Oral streptococci, such as Streptococcus mutans and Streptococcus sorbrinus, are considered to be the main etiological agents of tooth decay in children. Other bacteria, such as Prevotella spp. and Lactobacillus spp., and fungus, that is, Candida albicans, are related to the development and progression of ECC. Biomolecules in saliva, mainly proteins, affect the survival of oral microorganisms by multiple innate defensive mechanisms, thus modulating the oral microflora. Therefore, the protein composition of saliva can be a sensitive indicator for dental health. Resistance or susceptibility to caries may be significantly correlated with alterations in salivary protein components. Some oral microorganisms and saliva proteins may serve as useful biomarkers in predicting the risk and prognosis of caries. Current research has generated abundant information that contributes to a better understanding of the roles of microorganisms and salivary proteins in ECC occurrence and prevention. This review summarizes the microorganisms that cause caries and tooth-protective salivary proteins with their potential as functional biomarkers for ECC risk assessment. The identification of biomarkers for children at high risk of ECC is not only critical for early diagnosis but also important for preventing and treating the disease. | abdullah s hemadi rui-jie huang yuan zhou jing zou | 2017 | International Journal of Oral Science2017,9,4: | 18 |
| 2 | 治疗免疫性和炎症性眼病的免疫抑制剂显示文摘随着免疫学尤其是眼科免疫学的进展,出现了特异性强、更安全的免疫抑制剂,如环磷酰胺、苯丁酸氮芥、氨甲喋呤、咪唑硫嘌呤、环孢霉素A、溴隐亭、氨苯砜和秋水仙碱。这些药已成为治疗免疫性和炎症性眼病重要的和必不可少的药物。本文综述有关文献和经验,旨在使眼科医生更好地了解这些最常用的免疫抑制剂的特性。 | Ramzi Hemady 赵京城 | 1992 | 国外医学(眼科学分册)1992,16,1: | 4 |
| 3 | Catalytic synthesis and purification of carbon nanotubes显示文摘 | Hemadi K Fonseca A Nagy J B | 1996 | Synthetic Metals1996,77,: | 1 |
| 4 | Keratoconjunctivitis sicca and corneal ulcers显示文摘 | Hemady R Chu W Foster C S | 1990 | Cornea1990,9,2: | 1 |
| 5 | Intraocular penetration of ketoconazole in rabbits显示文摘 | Hemady RK Chu W Foster CS | 1992 | Cornea1992,11,4: | 1 |
| 6 | Normal remodeling of the oxygen-injured lung requires the cyclin- dependent kinase inhibitor p21 ( Cip1/ WAF1/Sdi1) 显示文摘 | Staversky R J Watkins RH Wright TW Hemady E LoMonaco MB D'Angio CT | 2002 | Am J Pathol2002,161,3: | 1 |
| 7 | Is there any correlation between stages of endometriosis and severity of chronic pelvic pain? Possibilities of treatment 显示文摘 | Szendei G Hemadi Z Devenyi N | 2005 | Gynecol Endocrinol2005,21,2: | 1 |
| 8 | Synthesis of MWNT-based composite materials with inorganic coating 显示文摘 | Hemadi K Ljubovic E Seo J W | 2003 | Acta Ma-ter2003,51,: | 1 |
| 9 | Penetrating eye injury in war显示文摘 | Biehl JW Valdez J Hemady RK | 1999 | Mil Med1999,164,11: | 1 |
| 10 | Duration of HPV associated risk for high grade cervical intraepithelial neoplasia显示文摘 | Hemadi Z Gazdag L Szoke K | 2006 | Eur J Obstet Gynecol Reprod Biol2006,125,1: | 1 |
| 11 | Synthesis of MWNT-based Composite Materials with Inorganic Coating 显示文摘 | Hemadi K Ljubovic E Seo JW | 2003 | Acta Materialia2003,51,5: | 1 |
| 12 | Growth and microstructure of catalytically produced coiled carbon nanotubes 显示文摘 | Hemadi K Thien - Nga L Forro L | 2001 | J Phys Chem B2001,105,12: | 1 |
| 13 | Sythesis of MWNT-based Composite Material with Inorganic Coating显示文摘 | Ljubovic E Seo J W | 2003 | Acta Materialia2003,51,: | 1 |
| 14 | Duraton of HPV-associated risk for high grade cervical intraepithelial neoplasia显示文摘 | Hemadi Z Gazdag L Szoke K | 2006 | Eur J Obstet Gynecol Reprod Bid2006,125,1: | 1 |
| 15 | Duraton of HPV-associated risk for high grade cervical intraepithelial neoplasia显示文摘 | Hemadi Z Gazdag L Szoke K | 2006 | Eur J Obstet Gynecol Reprod Biol2006,125,1: | 1 |
| 16 | Penetrating eye injury in war 显示文摘 | Biehl JW Valdez J Hemady RK | 1999 | Mil Med1999,64,11: | 1 |
| 17 | The Prognostic significance of HPV-16 genome status of the lymph nodes,the integration status and P53 genotype in HPV-16 positive cervical cancer:a long term follow up显示文摘 | Hemadi Z Szarka K Sapy T | 2005 | BJOG2005,110,2: | 1 |
| 18 | Effect of Melatonin on Proliferative Activity and Apoptosis in Spermatogenic Cells in Mouse under Chemotherapy显示文摘Objective To investigate the possible protective role of melatonin on the proliferative activity, and apoptosis of germ cells in chemotherapy-induced spermiotoxicity. Methods Male adult NMRI mice were divided into four groups. Then each group was divided into two subgroups of a and b. Group A (control): mice received vehicle (1% ethanol) for 5 d. Group B (busulfan): mice received a single dose of 20 mg/kg busulfan. Group C (melatonin): mice received melatonin (10 mg/kg) for 5 d. Group D (busulfan+melatonin): mice received a 5-day course of melatonin (10 mg/kg) following an initial dose of busulfan (20 mg/kg). Evaluations were made using bromodeoxyuridine (BrdU) labeling and in situ TUNEL assay after 5 d (subgroup a) or 35 d (subgroup b). Results Busulfan-treated mice both in subgroups a and b, showed a significant increase in the number of apoptotic cells (P<0.01) and decrease in BrdU labeling index (P<0.01) compared with controls. Melatonin in group C significantly decreased BrdU labeling index compared with the control (P<0.01). Melatonin in group D significantly reduced apoptosis rate and increased BrdU labeling index compared with group B. Conclusion Melatonin may have a protective effect against busulfan-induced testicular damage, partly by decreasing of apoptosis and alteration in proliferative activity of germ cells. | Fahimeh Mohamad Ghasemi Masoumeh Faghani Sina Khajehjahromi Mohamadhadi Bahadori Ebrahim Nasiri E Masoud Hemadi | 2010 | Journal of Reproduction and Contraception2010,21,2: | 1 |
| 19 | Is there any correlation between stages of endometriosis and severity of chronic pelvic pain? Possibilities of treatment 显示文摘 | Szendei G Hemadi Z Devenyi N | 2005 | Gynecol Endocrinol2005,21,: | 1 |
| 20 | Follicular dynamics inneonate vitrified ovarian grafts after host treatment withmelatonin显示文摘 | Hemadi M Saki G Shokri S | 2011 | Folia Morphol(Warsz)2011,70,1: | 1 |