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| 1 | Cytokine interplay among the diseased retina, inflammatory cells and mesenchymal stem cells-a clue to stem cell-based therapy显示文摘Retinal degenerative disorders,such as diabetic retinopathy,retinitis pigmentosa,age-related macular degeneration or glaucoma,represent the most common causes of loss of vision and blindness.In spite of intensive research,treatment options to prevent,stop or cure these diseases are limited.Newer therapeutic approaches are offered by stem cell-based therapy.To date,various types of stem cells have been evaluated in a range of models.Among them,mesenchymal stem/stromal cells(MSCs)derived from bone marrow or adipose tissue and used as autologous cells have been proposed to have the potential to attenuate the negative manifestations of retinal diseases.MSCs delivered to the vicinity of the diseased retina can exert local anti-inflammatory and repairpromoting/regenerative effects on retinal cells.However,MSCs also produce numerous factors that could have negative impacts on retinal regeneration.The secretory activity of MSCs is strongly influenced by the cytokine environment.Therefore,the interactions among the molecules produced by the diseased retina,cytokines secreted by inflammatory cells and factors produced by MSCs will decide the development and propagation of retinal diseases.Here we discuss the interactions among cytokines and other factors in the environment of the diseased retina treated by MSCs,and we present results supporting immunoregulatory and trophic roles of molecules secreted in the vicinity of the retina during MSC-based therapy. | Vladimir Holan Barbora Hermankova Magdalena Krulova Alena Zajicova | 2019 | World Journal of Stem Cells2019，11，11： | 2 |
| 2 | Sueeess rate of root canal treatment in primary molars显示文摘 | Moskovitz M Sammara E Holan G | 2005 | Journal of dentistry2005，33，1： | 1 |
| 3 | Learning patterns in venture capital investing in new industries 显示文摘 | Dimov D Holan P M Milanov H | 2012 | Industrial & Corporate Change2012，21，6： | 1 |
| 4 | Effects of mild chronic stress as model of depression on the immunoreactivity of C57BL/6 mice 显示文摘 | Basta-Kaim A Holan V | 1998 | Int J Immunopharmacol1998，20，12： | 1 |
| 5 | Cadmium biosorption Saccgarimyces cerevisiae 显示文摘 | Volesky B May H Holan Z R | 1993 | Biotech and Bioeng1993，41，8： | 1 |
| 6 | Biosorption of heavy metals显示文摘 | Volesky B Holan Z R | 1995 | Biotechnol Prog1995，11，3： | 1 |
| 7 | Bayesian multiregime smooth transition re-gression with ordered categorical variables 显示文摘 | WANG* HOLAN | 2012 | ComputationalStatistics Data Analysis2012，56，12： | 1 |
| 8 | Mannaging organizational forgetting显示文摘 | PABLO MARTIN DE HOLAN NELSON PHILLIPS THOM AS B LAWRENCE | 2004 | MIT Slon Management Review2004，，： | 1 |
| 9 | Biosorption of heavy metals( Cd, Cu, Ni, Pb, Zn) by chemically reinforced biomass of marine algae显示文摘 | Leusch A Holan Z R Volesky B | 1995 | J Chem Tech Biotechnol1995，62，3： | 1 |
| 10 | Biosorption of heavy metals (Cd, Cu, Ni, Pb, Zn) by chemically-reinforced biomass of marine algae显示文摘 | Leusch A Holan Z R Volesky B | 1995 | J Chem Tech Biotechnol1995，62，： | 1 |
| 11 | Biosorption of heavy metals显示文摘 | Volesky B Holan Z R | 1995 | Biotechnol Prog1995，11，： | 1 |
| 12 | Biosorption of heavy metals显示文摘 | Volesky B Holan Z R | 1995 | Biotechnol Prog1995，11，： | 1 |
| 13 | Synthesis and Relative Stereochem- istry of 2 -Monohalo DDT Pyrethroid Structures:2 -halo - 1 - (4' - ethoxypheny) cyclopropane - 1 - methanols and Cyclopropane - 1 - car- boxylic Acid and Esters显示文摘 | Johnson M P Holan G Karen E J | 1986 | Aust J Chem1986，39，： | 1 |
| 14 | Biosorption of cadmium by biomass of marine algae显示文摘 | Holan Z R Volesky B Prasetyo I | 1993 | Biotechnol Bioeng1993，41，： | 1 |
| 15 | Remembrance of things past? The dynamics of organizational forgetting 显示文摘 | De Holan P M Phillips N | 2004 | Management Science2004，50，： | 1 |
| 16 | Accumulation of cadmium,lead and nickel by fungal and wood biosorbents显示文摘 | Holan Z R Volesky B | 1995 | Applied Biochemistry and Biotechnology1995，53，： | 1 |
| 17 | Biosorption of cadmium by biomass of marine algae 显示文摘 | Holan Z R Volesky B Prasetyo I | 1993 | Biotech Bioeng1993，41，： | 1 |
| 18 | Biosorption of cadmium by biomass of marine algae显示文摘 | Holan Z R Volesky B Prasetyo I | 1993 | Biotechnology & Bioengi- neering1993，41，： | 1 |
| 19 | Relation between aetiology and treatment of leg uleers显示文摘 | Holan V | 1996 | Br J Surg1996，83，： | 1 |
| 20 | Learning patterns in venture capital investing in new industries显示文摘 | Dimov D de Holan P M Milanov H | 2012 | Industrial and Corporate Change2012，，21： | 1 |
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