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| 1 | Effect of rapamycin on hepatic osteodystrophy in rats with portasystemic shunting显示文摘瞄准:如果与推延的 portasystemic 有关的 T 房间激活通过 RANKL 依赖的小径引起调停骨破折的骨头损失,学习。如果用 rapamycin 的 T 房间抑制将在老鼠免于骨头损失,我们也调查了。方法:推延的 Portasystemic 在男 Sprague-Dawley 老鼠和 rapamycin 被执行 0.1 mg/kg 被管饲法为 15 wk 管理。老鼠收到了 powderized 食物并且补加喂在骨头作文上阻止营养不良的效果。重量获得和生长在推延的动物在外科以后被恢复。在结束,骨头周转和量的骨头组织学的生物化学的参数被估计。T 房间激活,煽动性的 cytokine 生产,和 RANKL 依赖的小径的标记被测量。另外, IGF-1 和性腺机能减退的角色被调查。结果:推延的 Portasystemic 引起了是 RANKL 独立人士的低周转骨质疏松症。包括 IL-1, IL-6 和 TNFalpha,骨头再吞 cytokine 层次没在浆液和 TNFalpha 被增加, RANKL 表示不起来在 PBMC 调整了。推延的 Portasystemic 增加了传播 CD8+T 房间人口。Rapamycin 减少了传播 CD8+T 房间人口,增加了 CD8+CD25+T 规章的房间人口并且改进了骨头周转的所有参数。结论:推延的 portasystemic 引起的骨质疏松症可以被 rapamycin 部分在肝的骨营养不良的老鼠模型改善。 | Schalk W van der Merwe Maria M Conradie Robert Bond Brenda J Olivier Elongo Fritz Martin Nieuwoudt Rhena Delport Tomas Slavik Gert Engelbrecht Del Kahn Enid G Shephard Maritha J Kotze Nico P de Villiers Stephen Hough | 2006 | World Journal of Gastroenterology2006，12，28： | 2 |
| 2 | Pancreatic lesions in yon Hippel-Lindau disease: prevalence, clinice significance, and CT findings 显示文摘 | Hough D M Stephens D H Johnson C D | 1994 | Am J Roentgenol1994，162，5： | 1 |
| 3 | Cloning and Overexpression in Escherichia coli of the Gene Encoding Citrate Synthase from the Hyperthermophilic Archaeon Sulfolobus solfataricus显示文摘 | Clnnaris H West S M Hough D W | 1998 | Extremophiles1998，2，2： | 1 |
| 4 | Internal connectivity of the homing pigeon (Columba livia) hippocampal formation:an anterograde and retrograde tracer study显示文摘 | Kahn M C Hough Ⅱ G E Eyck G R T | 2003 | J Comp Neurol2003，459，2： | 1 |
| 5 | Predictive Validity of a Multidisciplinary Model of Reemployment Success 显示文摘 | WANBERG C R HOUGH L M SONG Z L | 2002 | Journal of Applied Psych ology2002，87，6： | 1 |
| 6 | Conformational vari- ability of the Cu site in one subunit of bovine CuZn superoxide dismu- tase: the importance of mobility in the Glu119-Leu142 loop region for catalytic function显示文摘 | HOUGH M A STRANGE R W HASNAIN S S | 2000 | J Moi Bioi2000，304，2： | 1 |
| 7 | Autoimmune pancreatitis: differentiation from pancreatic carcinoma and normal pancreas on the basis of enhancement characteristics at dual-phase CT 显示文摘 | Takahashi N Fletcher J G Hough D M | 2009 | AJR Am J Roentgenol2009，193，2： | 1 |
| 8 | Optimal Guidance and Non linear Estimation for Interception of Decelerating Targets显示文摘 | Hough M E | 1995 | Journal of Guidance Control and Dynamics (S0731-5090)1995，18，2： | 1 |
| 9 | Personnel selection:looking toward the future-remembering the past 显示文摘 | Hough L M Oswald F L | 2000 | Annual Review of Psychology2000，5，1： | 1 |
| 10 | Diamonds from the iridium-rich K-T boundary layer at Arroyo el Mimbral, Tamaulipas, Mexico显示文摘 | Hough R M Gilmour I Pillinger C T | 1997 | Geology1997，25，11： | 1 |
| 11 | Middle ear electromagnetic semi - implantable hearing device : resuhs of the phase II SOUNDTEC direct system clinical trial 显示文摘 | Hough J V Matthews P Wood M W | 2002 | Otol Neurotol2002，23，6： | 1 |
| 12 | Do Impression Man- agement Scales in Personality Inventories Predict Manage- rial Job Performance Ratings? 显示文摘 | Viswesvaran C Ones D S Hough L M | 2001 | International Journal of Selection and Assessment2001，9，4： | 1 |
| 13 | Nonlinear recursive filter for boost trajectories 显示文摘 | Hough M E | 2001 | The Journal of Guidance Control and Dynamics2001，24，5： | 1 |
| 14 | Scanning Actions and Environmental Dynamism: Gathering Information for Strategic Decision Making 显示文摘 | Hough J R White M A | 2004 | Management Decision2004，42，6： | 1 |
| 15 | Optimal guidance and nonlinear estimation for interception of decelerating targets 显示文摘 | Hough M E | 1995 | The Journal of Guidance Control and Dynamics1995，18，2： | 1 |
| 16 | Mapping of CD24 and homologous sequences to multiple chromosomal loci显示文摘 | ROSTEN P M SEXTON T L | 1994 | Genomics1994，22，1： | 1 |
| 17 | Identifyingsource correction parameters for hydrocarbon wastes usingcompound specific isotope analysis显示文摘 | Hough R L Whittaker M Fallick A E et a1 | 2006 | Environmental Pollu-tion2006，143，： | 1 |
| 18 | Autoim- mune panereatitis: differentiation from pancreatic carcino- ma and normal pancreas on the basis of enhancement characteristics at dual-phase CT 显示文摘 | Takahashi N Fletcher J G Hough D M | 2009 | Am J Roentgenol2009，193，2： | 1 |
| 19 | Optimal Guidance and Nonlinear Estimation for Interception of Accelerating Targets显示文摘 | HOUGH M E | 1995 | Journal of Guidance Control and Dynamics1995，18，5： | 1 |
| 20 | Effects of Intentional Distortion in Personality Measurement and Evaluation of Suggested Palliatives 显示文摘 | Hough Leaetta M | 2000 | Human Performance2000，，23： | 1 |
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