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| 1 | Passive expansion of sub-maximally dilated transjugular intrahepatic portosystemic shunts and assessment of clinical outcomes显示文摘AIM To assess for passive expansion of sub-maximally dilated transjugular intrahepatic portosystemic shunts(TIPS) and compare outcomes with maximally dilated TIPS.METHODS Polytetrafluoroethylene covered TIPS(Viatorr) from July 2002 to December 2013 were retrospectively reviewed at two hospitals in a single institution. Two hundred and thirty patients had TIPS maximally dilated to 10 mm(m TIPS), while 43 patients who were at increased risk for hepatic encephalopathy(HE), based on clinical evaluation or low pre-TIPS portosystemic gradient(PSG), had 10 mm TIPS sub-maximally dilated to 8 mm(sm TIPS). Group characteristics(age, gender, Model for End-Stage Liver Disease score, post-TIPS PSG and clinical outcomes were compared between groups, including clinical success(ascites or varices), primary patency,primary assisted patency, and severe post-TIPS HE. A subset of fourteen patients with sm TIPS underwent follow-up computed tomography imaging after TIPS creation, and were grouped based on time of imaging(< 6 mo and > 6 mo). Change in diameter and crosssectional area were measured with 3D imaging software to evaluate for passive expansion.RESULTS Patient characteristics were similar between the sm TIPS and m TIPS groups, except for pre-TIPS portosystemic gradient, which was lower in the sm TIPS group(19.4 mm Hg ± 6.8 vs 22.4 mm Hg ± 7.1, P = 0.01). Primary patency and primary assisted patency between sm TIPS and m TIPS was not significantly different(P = 0.64 and 0.55, respectively). Four of the 55 patients(7%) with sm TIPS required TIPS reduction for severe refractory HE, while this occurred in 6 of the 218 patients(3%) with m TIPS(P = 0.12). For the 14 patients with follow-up computed tomography(CT) imaging, the median imaging follow-up was 373 d. There was an increase in median TIPS diameter, median percent diameter change, median area, and median percent area change in patients with CT follow-up greater than 6 mo after TIPS placement compared to follow-up within 6 mo(8.45 mm, 5.58%, 56.04 mm^2, and 11.48%, respectively, P = 0.01).CONCLUSION Passive expansion of sm TIPS does occur but clinical outcomes of sm TIPS and m TIPS were similar. Sub-maximal dilation can prevent complications related to overshunting in select patients. | Michael C Hsu Charles N Weber S William Stavropoulos Timothy W Clark Scott O Trerotola Richard D Shlansky Goldberg Michael C Soulen Gregory J Nadolski | 2017 | World Journal of Hepatology2017，9，12： | 11 |
| 2 | Magnetic resonance imag-ing results can affect therapy decisions in hyperacute stroke care显示文摘 | Heidenreich J O Hsu D Wang G | | 0，，： | 1 |
| 3 | Quantum dot nanoparticies affect the reproductive system of Caenorhabditis elegans显示文摘 | Hsu P C O'Callaghan M Al- Salim N | 2012 | Environmental Toxicology and Chemistry2012，31，10： | 1 |
| 4 | Tuberculous kyphosis: correction with spinal osteotomy, halo-pelvic distraction, and anterior and posterior fusion显示文摘 | Yau AC Hsu LC O'Brien JP | 1974 | J Bone Joint Surg Am1974，56，7： | 1 |
| 5 | Immunohistochemical and clinical characterization of the basal-like subtype of invasive breast carcinoma显示文摘 | NIELSEN T O HSU F D JENSEN K | 2004 | Clin Cancer Res2004，10，16： | 1 |
| 6 | Induction of calcification in rabbit aortas by high cholesterol diets: roles of calcifiable vesicles in dystrophic calcification显示文摘 | Hsu H H Camaeho N C Tawfik O | 2002 | Atherosclerosis2002，161，1： | 1 |
| 7 | Microcracking of Plain Concrete and the Shape of the Stress-Strain Curve显示文摘 | T T C Hsu F O Slate G M Sturman | 1963 | ACI Materials Journal1963，60，2： | 1 |
| 8 | Effects of lectins on calcification by vesicles isolated from aortas of cholesterol-fed rabbits显示文摘 | Hsu HHT Tawfik O Sun F | 2000 | Biochemica Biophysica Acta2000，1464，4： | 1 |
| 9 | Robotic-assisted laparo- scopic myomectomy compared with standard laparoscopic myomectomy-a retrospective matched control study 显示文摘 | Nezhat C Lavie O Hsu S | 2009 | Fertil Steri12009，91，2： | 1 |
| 10 | The effects of hydro- thermal temperature and thickness of TiC2 film on the performance of a dye-sensitized solar cell显示文摘 | Huang O Y Hsu Y C Chen J G | 2006 | Sol Energ Mat Sol (32006，90，5： | 1 |
| 11 | and clini- cal chara - cterization of the basal - like subtype of invasive breast carcinoma 显示文摘 | Nielsen T O Hsu F D Jansen K | 2004 | Clin Cancer Res2004，10，16： | 1 |
| 12 | Critical role for galectin-3in airway inflammation and bronchial hyperresponsiveness in a murine model of asthma显示文摘 | Zuberi RI Hsu DK Kalayci O | | 0，，06： | 1 |
| 13 | Purification and characterization of human tissue prokllikrein and kallikrein isoforms expressed in Chinese hamster ovary cells 显示文摘 | Lu H S Hsu Y R Narhi L O | 1996 | Protein Expression and Purification1996，8，： | 1 |
| 14 | Peripheral vascular disease risk factors among patients undergoing hemodialysis 显示文摘 | O'Hare A Hsu CY Bacchetti P | 2002 | J Am Soc Nephrol2002，13，： | 1 |
| 15 | InGaAs pin detector array integrated with AlGaAs/GaAs grating demultiplexer by total internal reflector 显示文摘 | HSU S H KING O JOHNSON F G | 1999 | Electronics Letters1999，35，7： | 1 |
| 16 | Immunohistochemical and clinical characterization of the basal-like subtype of invasive breast carcinoma 显示文摘 | Nielsen T O Hsu F D Jensen K | 2004 | Clin Cancer Res2004，10，16： | 1 |
| 17 | Microcracking of plain concrete and the shape of the stress-strain curve显示文摘 | Hsu T T C Slate F O Sturman G M et el | 1963 | Material Journal1963，60，2： | 1 |
| 18 | Immunohistochemieal and clinical characterization of the basal-like subtype of invasive breast carcinoma显示文摘 | Nielsen T O Hsu F D Jansen K | 2004 | Clin Cancer Res2004，10，16： | 1 |
| 19 | Tensile bond strength between aggregate and cement paste or mortar显示文摘 | HSU T T C SLATE F O | 1963 | ACI1963，60，4： | 1 |
| 20 | Linkage of the loeus for cerebral cavernous hemagiomas to human chromosome79 in four families of Mexican-American descent显示文摘 | Polymeropoulos MH Hurko O Hsu F | 1997 | Neurolo- gy1997，48，： | 1 |
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