|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 进展期胃癌行腹腔镜与开腹D2远端胃癌根治术的并发症发生率和死亡率的随机对照研究显示文摘目的腹腔镜根治性远端胃切除(radical laparoscopic distal gastrectomy,LG)+D2淋巴结清扫术用于治疗进展期胃癌其安全性和有效性仍存在争议。本研究设计了一个前瞻性随机对照研究来对比腹腔镜手术和传统开腹手术行根治性远端胃切除术+D2淋巴结清扫术在治疗进展期胃癌的安全性和疗效。研究对象和方法自2012年9月至2014年12月,1056例临床分期为T(2-4a)N0-3M0的胃癌患者被纳入本研究。患者被随机分为腹腔镜根治性远端胃切除术+D2淋巴清扫组(LG组)(n=528)和开腹远端胃切除术(open gastrectomy,OG)+D2淋巴清扫组(OG组)(n=528)。共有15位来自中国14个研究中心的经验丰富的外科医生参与此次研究。根据意向性治疗分析原则比较LG组(n=519)和OG组(n=520)手术后30天内的并发症发生率和死亡率。术后并发症严重程度分级根据Clavien-Dindo分级方法。结果 LG组和OG组患者的D2淋巴结清扫术的合格率相似(99.4%vs.99.6%;P=0.845)。术后并发症发生率在LG组为15.2%,OG组为12.9%,统计学无明显差异(相差2.3%,95%CI:-1.9-6.6,P=0.285)。死亡率在LG组为0.4%,而OG组无一例死亡(相差0.4%,95%CI:-0.4-1.4,P=0.249)。两组并发症的严重程度分布相似(P=0.314)。结论有经验的外科医生可以在进展期胃癌患者上安全开展腹腔镜下根治性远端胃切除术+D2淋巴结清扫。 | Hu Y Huang C Sun Y 戴伟钢 | 2016 | 消化肿瘤杂志(电子版)2016，8，3： | 202 |
| 2 | 代谢健康的肥胖和腹型肥胖与高血压风险增加相关显示文摘代谢健康型肥胖是指具有正常代谢特征的肥胖人群。研究者在中国农村地区队列研究(the rural Chinese cohort study)的成年人中,探究了代谢健康型肥胖与高血压风险的关系。这项前瞻性队列研究纳入中国成人9137名,在基线时(2007-2008年)无高血压、2型糖尿病或血脂异常,在2013-2014年进行随访。 | 周卫(译) 袁源(审校) Zhao Y Qin P Sun HH Liu Y Liu D Zhou Q Guo C Li Q Tian G Wu X Hu D Sun X Zhang M | 2020 | 中华高血压杂志2020，28，9： | 7 |
| 3 | Purified human bone marrow multipotent mesenchymal stem cells regenerate infarcted myocardium in experimental rats显示文摘 | Zhang S Jia Z Ge J Gong L Ma Y Li T Guo J Chen P Hu Q Zhang P Liu Y Li Z Ma K Li L Zhou C | 2006 | 中国生物学文摘2006，20，5： | 5 |
| 4 | Sol-gel derived HA/TiO_2 double coatings on Ti scaffolds for orthopaedic applications显示文摘Hydroxyapatite/titania (HA/TiO2) double layers were coated onto Ti scaffolds throughout for orthopaedic applications by sol-gel method. Differential scanning calorimetry (DSC), thermogravimetric analysis (TG) and X-ray diffractometry (XRD) were used for the characterisation of the phase transformations of the dried gels and coated surface structures. Scanning electron microscope (SEM) equipped with energy dispersive spectrometry (EDS) was used for the observation and evaluation of the morphology and phases of the surface layers and for the assessment of the in vitro tests. The in vitro assessments were performed by soaking the HA/TiO2 double coated samples into the simulated body fluid (SBF) for various periods. The TiO2 dipping-coating method at a speed of 12 cm/min, followed by a heat treatment at 600 ℃ for 20 min. The HA la lyaeyre wr wasa ssu cbosaetqeude bnytl ya dipping-coated on the outer surface at the same speed and then heat-treated at difference temperatures. The results indicat that the HA phase begins to crystallize after a heat treatment at 560 ℃. The crystallinity increases obviously at 760 ℃. SEM observations find no delamination or crack at the interfaces of HA/TiO2 and TiO2/Ti. The HA/TiO2 coated Ti scaffolds displays excellent bone-like apatite forming ability when it is soaked into SBF. Ti scaffolds after HA/TiO2 double coatings can be anticipated as promising implant materials for orthopaedic | XU W HU W Y LI M H MA Q Q P. D. HODGSON WEN C E | 2006 | 中国有色金属学会会刊:英文版2006，16，B01： | 5 |
| 5 | Common non-synonymous polymorphisms in the BRCA1 Associated RING Domain (BARD1) gene are associated with breast cancer susceptibility:a case-control analysis显示文摘The BRCA1 Associated RING Domain(BARD1) gene has been identified as a high penetrance gene for breast cancer, whose germline and somatic mutations were reported in both non-BRCA1/2 hereditary site-specific and sporadic breast cancer cases. BARD1 plays a crucial role in tumor repression, along with its heterodimeric partner BRCA1. In the current study, we tested the hypothesis that common non-synonymous polymorphisms in BARD1 are associated with breast cancer susceptibility in a case-control study of 507 patients with incident breast cancer and 539 frequency-matched cancer-free controls in Chinese women. We genotyped all three common(minor allele frequency (MAF) > 0.10) non-synonymous polymorphisms(Pro24Ser, Arg378Ser, and Val507Met) in BARD1. We found that the BARD1 Pro24Ser variant genotypes(24Pro/Ser and 24Ser/Ser) and Arg378Ser variant homozygote 378Ser/Ser were associated with a significantly decreased breast cancer risk, compared with their wild-type homozygotes, respectively. Furthermore, a significant locus-locus interaction was evident between Pro24Ser and Arg378Ser (P-int = 0.032). Among the 378Ser variant allele carriers, the 24Pro/Pro wild-type homozygote was associated with a significantly increased breast cancer risk (adjusted OR = 1.81, 95% CI = 1.11-2.95), but the subjects having 24Pro/Ser or Ser/Ser variant genotypes had a significantly decreased risk(adjusted OR = 0.74, 95% CI = 0.56-0.99). In stratified analysis, this locus-locus interaction was more evident among subjects without family cancer history, those with positive estrogen receptor (ER) and individuals with negative progesterone receptor(PR). These findings indicate that the potentially functional polymorphisms Pro24Ser and Arg378Ser in BARD1 may jointly contribute to the susceptibility of breast cancer. | Huo, X Hu, Z. B Zhai, X. J Wang, Y Wang, S Wang, X. C Qin, J. W Chen, W. S Jin, G. F Liu, J. Y Gao, J Wei, Q. Y Wang, X. R Shen, H. B | 2007 | 南京医科大学学报(自然科学版)2007，27，7： | 3 |
| 6 | Terahertz Semiconductor Quantum Well Devices显示文摘For eventually providing terahertz science with compact and convenient devices,terahertz (1~10THz) quantum-well photodetectors and quantum-cascade lasers are investigated.The design and projected detector performance are presented together with experimental results for several test devices,all working at photon energies below and around optical phonons.Background limited infrared performance (BLIP) operations are observed for all samples (three in total),designed for different wavelengths.BLIP temperatures of 17,13,and 12K are achieved for peak detection frequencies of 9.7THz(31μm),5.4THz(56μm),and 3.2THz(93μm),respectively.A set of THz quantum-cascade lasers with identical device parameters except for doping concentration is studied.The δ-doping density for each period varies from 3.2×1010 to 4.8×1010cm-2.We observe that the lasing threshold current density increases monotonically with doping concentration.Moreover,the measurements for devices with different cavity lengths provide evidence that the free carrier absorption causes the waveguide loss also to increase monotonically.Interestingly the observed maximum lasing temperature is best at a doping density of 3.6×1010cm-2. | Liu H C Luo H Ban D Waichter M Song C Y Wasilewski Z R Buchanan M Aers G C SpringThorpe A J Cao J C Feng S L Williams B S Hu Q | 2006 | Journal of Semiconductors2006，27，4： | 2 |
| 7 | Natural Convective Boiling in Vertical Rectangular Narrow Channels 显示文摘 | Xia C Hu W Guo Z Y | 1996 | Experimental Thermal and Fluid Science1996，12，： | 2 |
| 8 | The influence of apoptosis of mucosal epithelial cells on intestinal barrier integrity after scald in rats显示文摘 | Zhang C Sheng Z Y Hu S | 2002 | Burns2002，28，8： | 2 |
| 9 | Reduction and restoration of mitochondrial DNA content after focal cerebral ischemia/ reperfusion 显示文摘 | Chen H Hu C J He Y Y | 2001 | Stroke2001，32，10： | 1 |
| 10 | Does dying at home influence the good death of terminal cancer patients? 显示文摘 | Yao C A Hu W Y Lai Y F | 2007 | J Pain Symptom Manage2007，34，5： | 1 |
| 11 | sinensis: regeneration and characterization of hybrid shoots显示文摘 | XU X Y HU Z Y LI J F et aL Asymmetric somatic hybridization between UV-irradiated Citrus unshiu and C | 2007 | Plant Cell Reports2007，26，： | 1 |
| 12 | Specific expression of the AGL1 MADS- box gene suggests regulatory functions in Arabidopsis gynoecium and ovule development显示文摘 | Flanagan C A Hu Y Ma H | 1996 | Plant J1996，，10： | 1 |
| 13 | Activated carbon addition toa submerged anaerobic membrane bioreactor: effect on performance, trans- membrane pressure, and flux 显示文摘 | Hu A Y Stuckey D C | 2007 | Joumal of Environmental Engineering - ASCE2007，133，1： | 1 |
| 14 | Face recognition using laplacianfaces显示文摘 | HE X F Y AN S C HU Y | 2005 | IEEE Trans on Pattern Analysis anti Machine Intelligence2005，27，3： | 1 |
| 15 | RNA-binding protein insulin-like growth factor Ⅱ mRNA-binding protein 3 expression promotes tumor invasion and predicts early recurrence and poor prognosis in hepatocellular carcinoma显示文摘 | Jeng Y M Chang C C Hu F C | 2008 | Hepatology2008，48，4： | 1 |
| 16 | Photografting of poly(hydroxylethyl acrylate) onto porous polyurethane scaffolds to improve their endothelial cell compatibility显示文摘 | Hu X Hong Y | 2003 | J Biomater Sci Polyni Ed2003，14，9： | 1 |
| 17 | Study of the adsorption behavior of heavy metal ions on nanometer-size titanium dioxide with ICP-AES显示文摘 | QIN Y C HU B | 2000 | FreseniusJ Anal Chem2000，368，： | 1 |
| 18 | Quantification of Halocene Asian monsoon rainfall from spatially separated cave record 显示文摘 | Hu C Y Henderson G M Huang J H | 2008 | Earth Planet Sci Lett2008，266，： | 1 |
| 19 | The relationship between coronary ar tery disease and abnormal glucose regulation in China: the China Heart Survey显示文摘 | Hu D Y Pan C Y Yu J M | 2006 | Eur Heart J2006，27，21： | 1 |
| 20 | Investigation on gasoline deep desulfurization for fuel cell applications显示文摘 | Zhang J C Song L F Hu J Y | 2005 | Energy Convers Manage2005，46，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员