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1Radioembolization for the treatment of unresectable hepatocellular carcinoma:A clinical review显示文摘Hepatocellular carcinoma(HCC)is the sixth most common cancer in the world.The majority of patients with HCC present with unresectable disease.These patients have historically had limited treatment options secondary to HCC demonstrating chemoresistance to the currently available systemic therapies.Additionally, normal liver parenchyma has shown intolerance to tumoricidal radiation doses,limiting the use of external beam radiation.Because of these limitations,novel percutaneous liver-directed therapies have emerged. The targeted infusion of radioactive microspheres (radioembolization)represents one such therapy. Radioembolization is a minimally invasive transcatheter therapy through which radioactive microspheres are infused into the hepatic arteries that supply tumor. Once infused,these microspheres traverse the hepatic vascular plexus and selectively implant within the tumor arterioles.Embedded within the arterioles, the 90Y impregnated microspheres emit high energy and low penetrating radiation doses selectively to the tumor.Radioembolization has recently shown promise for the treatment of patients with unresectable HCC. The objective of this review article is to highlight twocurrently available radioembolic devices(90Y,188Rh)and provide the reader with a recent review of the literature.Saad M Ibrahim Robert J Lewandowski Kent T Sato Vanessa L Gates Laura Kulik Mary F Mulcahy Robert K Ryu Reed A Omary Riad Salem 2008World Journal of Gastroenterology2008,14,11:14
2Highly efficient derivation of ventricular cardiomyocytes from induced pluripotent stem cells with a distinct epigenetic signature显示文摘从 pluripotent 干细胞导出的 Cardiomyocytes 能在药测试,疾病建模和基于房间的治疗被使用。没有 procardiogenic 生长因素,然而,从 pluripotent 干细胞的 cardiomyogenesis 的效率通常是低的,产生 cardiomyocyte 人口是异构的。这里,我们证明导致的 pluripotent 干细胞( iPSCs )能从鼠科的室的 myocytes ( VM )被导出,并且与从各种各样的体的房间类型导出的 iPSCs 的另外的报告一致,自发地作为与遗传上匹配的胚胎的干细胞(转换字符)或 iPSCs 相比区分 cardiomyocytes 进跳动的显著地更高的倾向从尾巴尖端成纤维细胞导出的 导出VM 的 iPSCs ( ViPSCs )展览。惊人地,导出 ViPSC 的 cardiomyocytes 显示的多数室的显型。在 ViPSCs 的提高的室的 myogenesis 在区别的早阶段经由心血管的祖先的增加的数字被调停。以便从 ViPSCs 调查提高的室的 myogenesis 的机制,我们执行了全球基因表示和 DNA methylation 分析,它揭示了可以涉及在 pluripotent 干细胞指定 VM 命运的不同 epigenetic 签名。Huansheng Xu B Alexander Yi Hao Wu Christoph Bock Hongcang Gu Kathy O Lui Joo-Hye C Park Ying Shao Alyssa K Riley Ibrahim J Domian Erding Hu Robert Willette John Lepore Alexander Meissner Zhong Wang Kenneth R Chien 2012Cell Research2012,22,1:7
3Ethylene-inhibiting compound 1-MCP delays leaf senescence in cotton plants under abiotic stress conditions显示文摘Cotton(Gossypium hirsutum L.) plants produce more ethylene when subjected to abiotic stresses, such as high temperatures and drought, which result in premature leaf senescence, reduced photosynthetic efficiency, and thus decreased yield. This study was conducted to test the hypothesis that the ethylene-inhibiting compound 1-methylcyclopropene(1-MCP) treatment of cotton plants can delay leaf senescence under high temperature, drought, and the aging process in controlled environmental conditions. Potted cotton plants were exposed to 1-MCP treatment at the early square stage of development. The protective effect of 1-MCP against membrane damage was found on older compared to younger leaves, indicating 1-MCP could lower the stress level caused by aging. Application of 1-MCP resulted in reduction of lipid peroxidation, membrane leakage, soluble sugar content, and increased chlorophyll content, in contrast to the untreated plants under heat stress, suggesting that 1-MCP treatment of cotton plants may also have the potential to reduce the effect of heat stress in terms of delayed senescence. Application of 1-MCP caused reductions of lipid peroxidation, membrane leakage, and soluble sugar content, together with increases in water use efficiency(WUE), water potential, chlorophyll content, and fluorescence quantum efficiency, compared to the untreated plants under drought, suggesting that 1-MCP treatment of cotton plants may also have the ability to reduce the level of stress under drought conditions. In conclusion, 1-MCP treatment of cotton should have the potential to delay senescence under heat and drought stress, and the aging process. Additionally, 1-MCP is more effective under stress than under non-stress conditions.CHEN Yuan J T Cothren CHEN De-hua Amir M H Ibrahim Leonardo Lombardini 2015Journal of Integrative Agriculture2015,14,7:3
4Perioperative risk factors associated with delayed graft function following deceased donor kidney transplantation:A retrospective,single center study显示文摘BACKGROUND There is an abundant need to increase the availability of deceased donor kidney transplantation(DDKT)to address the high incidence of kidney failure.Challenges exist in the utilization of higher risk donor organs into what appears to be increasingly complex recipients;thus the identification of modifiable risk factors associated with poor outcomes is paramount.AIM To identify risk factors associated with delayed graft function(DGF).METHODS Consecutive adults undergoing DDKT between January 2016 and July 2017 were identified with a study population of 294 patients.The primary outcome was the occurrence of DGF.RESULTS The incidence of DGF was 27%.Under logistic regression,eight independent risk factors for DGF were identified including recipient body mass index≥30 kg/m^(2),baseline mean arterial pressure<110 mmHg,intraoperative phenylephrine administration,cold storage time≥16 h,donation after cardiac death,donor history of coronary artery disease,donor terminal creatinine≥1.9 mg/dL,and a hypothermic machine perfusion(HMP)pump resistance≥0.23 mmHg/mL/min.CONCLUSION We delineate the association between DGF and recipient characteristics of preinduction mean arterial pressure below 110 mmHg,metabolic syndrome,donorspecific risk factors,HMP pump parameters,and intraoperative use of phenylephrine.Nicholas V Mendez Yehuda Raveh Joshua J Livingstone Gaetano Ciancio Giselle Guerra George W Burke III Vadim B Shatz Fouad G Souki Linda J Chen Mahmoud Morsi Jose M Figueiro Tony M Ibrahim Werviston L DeFaria Ramona Nicolau-Raducu 2021World Journal of Transplantation2021,11,4:2
5Modelling of Electromagnetically Excited Turbulent Flow of Molten Metal in a TwinChannel Induction Furnace显示文摘Ghojel J Ibrahim R N 2006Progress in Computational Fluid Dynamics2006,,7:1
6Shear transfer in reinforced concrete显示文摘Hofbeck J A Ibrahim I O Mattock A H 1969ACI Journal Proceedings1969,66,2:1
7Particulate Reinforced Metal Matrix Composites显示文摘Ibrahim I A Mohamed F A Lavernia E J 1991Mater Sci1991,26,:1
8Pharmacokinetics of inhaled rifampicin porous particles for tuberculosis treatment: insight into rifampicin absorption from the lungs of guinea pigs显示文摘Garcia Contreras L Sung J Ibrahim M 2015Mol Pharrn2015,12,8:1
9Determining propoxur and other carbamates in meat using HPLC fluorescence and gas chromatography/Ion trap mass spectrometry after supercritical fluid extraction显示文摘ARGAUER J ELLER K I IBRAHIM M A 1995Journal of Agricultural and Food Chemistry1995,43,10:1
10A multi -criteria approach to contractor selection 显示文摘IBRAHIM M M MIKE J R SAMI M F 2002Engi- neering Construction and Architectural Management2002,9,1:1
11Rapid determination of chloramphenicol and its glucuronide in food products by liquid chromatography-electrospray negative ionization tandem mass spectrometry显示文摘Bogusz M J Hassan H A1-Enazi E Ibrahim Z A1-Tufail M 2004Journal of Chromatography B2004,807,:1
12Neutralization of infectivity of diverse R5 clinical isolates of human immunode ciency virus type 1 by gp120-binding 2'F-RNA aptamers显示文摘Khati M Schüman M Ibrahim J 2003J Virol2003,77,12:1
13Bayesian variable selection for proportionalhazards models 显示文摘Ibrahim J G Chen M H Maceachern S N 1999The Canadian Journal of Statists1999,27,4:1
14Gene-expression profiling of the early stages of MOG-induced EAE proves EAE-resistance as an active process显示文摘Mix E Ibrahim S Pahnke J 2004J Neuroimmunol2004,151,:1
15Study and Design of a Hybrid Wind-diesel-compressed AirEnergy Storage System for Remote Areas显示文摘H Ibrahim R Younfes A Ilinca M Dimitrova J Perron 2010Applied En-ergy2010,87,5:1
16Interferomettic technique to measure biomechanical changes in the cornea induced by refractive surgery 显示文摘Jaycock PD Lobo L Ibrahim J Tyrer J Marshall J 2005J Cataract Refract Surg2005,31,1:1
17Processing techniques for particulate-reinforced metal aluminum matrix composites显示文摘Srivatsan T S Ibrahim I A Mohamed F A Lavernia J 1991Journal of Materials Science1991,26,22:1
18Predictive model selection 显示文摘Laud P W and Ibrahim J G 1995Journal of the Royal Statistical Society (Series B)1995,57,:1
19The modeling of realistic chemicalvapor infiltration/deposition reactors显示文摘Ibrahim J Paolucci S 2010InternationalJournal for Numerical Methods in Fluids2010,64,5:1
20Nonlinear flutter of orthotropie composite panel under aerodynamic heating显示文摘Abbas J F Ibrahim R A Gibson R F 1993AIAAJournal1993,31,8:1
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