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| 1 | A machine learning approach to model solute grain boundary segregation显示文摘Even minute amounts of one solute atom per one million bulk atoms may give rise to qualitative changes in the mechanical response and fracture resistance of modern structural materials.These changes are commonly related to enrichment by several orders of magnitude of the solutes at structural defects in the host lattice.The underlying concept—segregation—is thus fundamental in materials science.To include it in modern strategies of materials design,accurate and realistic computational modelling tools are necessary.However,the enormous number of defect configurations as well as sites solutes can occupy requires models which rely on severe approximations.In the present study we combine a high-throughput study containing more than 1 million data points with machine learning to derive a computationally highly efficient framework which opens the opportunity to model this important mechanism on a routine basis. | Liam Huber Raheleh Hadian Blazej Grabowski Jörg Neugebauer | 2018 | npj Computational Materials2018,,1: | 2 |
| 2 | Effect of replacement of silica flour with silica fume on enginerring properties of oilwell cements at normal and elevated temperatures and pressure显示文摘 | Grabowski E Gillott J E | 1989 | Cement and Concrete Research1989,19,3: | 2 |
| 3 | 化疗所致恶心呕吐对复发性卵巢癌患者预后的影响:纳入1213例患者数据的meta分析结果显示文摘背景与目的 本研究旨在研究化疗所致恶心呕吐(chemotherapy-induced nausea and vomiting,CINV)对化疗药物剂量减少、中止以及患者生存获益的潜在影响。方法 本研究基于德国东北妇科肿瘤学会(North-Eastern German Society of Gynecological Oncology,NOGGO)开展的3项Ⅱ/Ⅲ期临床试验中的1213例复发性卵巢癌患者的原始数据,进行了个体病例数据的meta分析。通过Logistic回归和Cox回归分析,对年龄、ECOG评分、化疗周期数、复发次数、并发症以及不同研究等因素进行校正后,评估相应的比值比和风险比(hazard ratio,HR)。结果 大多数(58.1%)患者发生了恶心,且近三分之一(31.0%)的患者出现呕吐。CINV的发生与FIGO分期、分级、组织学以及复发次数无关;必须的化疗药物减量和中止化疗与恶心、呕吐的发生亦无相关性(P=0.88,P=0.39;P=0.25,P=0.54)。发生Ⅲ/Ⅳ级恶心呕吐患者的无进展生存期更短(P=0.02,Ⅲ/Ⅳ级恶心的HR=1.58,95%CI:1.14–2.20;P=0.02,Ⅲ/Ⅳ级呕吐的HR=1.67,95%CI:1.15–2.42)。发生Ⅲ/Ⅳ级恶心和呕吐的患者生存期较短(P <0.001,Ⅲ/Ⅳ级恶心的HR=2.35,95%CI:1.64–3.37;P <0.001,Ⅲ/Ⅳ级呕吐的HR=1.67,95%CI:1.15–2.42)。结论 CINV与复发性卵巢癌患者较差的预后显著相关,而与必须的化疗药物减量和中止无相关性。本研究强调CINV防治是早期最佳支持治疗的重要环节。 | Hannah Woopen R Richter R Chekerov G Inci S Alavi J P Grabowski J Sehouli 尹如铁(译) | 2022 | 癌症2022,41,6: | 2 |
| 4 | Conformance testing with TTCN显示文摘 | Schieferdecker I Grabowski J | 2000 | Telektronikk Languages for Telecommunication Applications2000,96,4: | 1 |
| 5 | Adenoid cystic breast carcinoma: is axillary staging necessary in all cases? Results from the California Cancer Registry 显示文摘 | Thompson K Grabowski J Saltzstein SL | 2011 | Breast J2011,17,: | 1 |
| 6 | A very fast tabu search algorithm for the permutation flow-shop problem with makespan criterion 显示文摘 | GRABOWSKI J WODECKI M | 2004 | Computers & Operations Research2004,31,11: | 1 |
| 7 | The Distribution of Sales Revenues from Pharmaceutical Innovation显示文摘 | Grabowski HG Vernon J | 2000 | Pharmacoeconomics2000,18,1: | 1 |
| 8 | Agonist-like or antagonist-like treatment for cocaine dependence with methadone for heroin dependence:two double-blind randomized clinical trials显示文摘 | Grabowski J Rhoades H Stotts A | 2004 | Neuropsychopharmacology2004,29,5: | 1 |
| 9 | The price of innovation: new estimates of drug development costs显示文摘 | DiMasi J A Hansen R W Grabowski H G | 2003 | J Health Econ2003,,22: | 1 |
| 10 | Comparative study of the ender method and dynamic hip screw stabilization in the treatment of intertrochanteric fractures of the femur 显示文摘 | Walo R Semenowicz J Grabowski M | 2003 | Orthop Traumatol Rehabil2003,5,1: | 1 |
| 11 | Self-splicing RNA: autoexcision and autocyciization of the ribosomal RNA intervening sequence ofTetrahymena 显示文摘 | KRUGER K GRABOWSKI P J ZAUG A J | 1982 | Cell1982,31,1: | 1 |
| 12 | Effect of hydrochlorothiazide on the pharmacokinetics and pharmacodynamics of febuxostat,a non-purine selective inhibitor of xanthine oxidase显示文摘 | Grabowski B Khosravan R Wu J T | | 0,,01: | 1 |
| 13 | New block properties for the permutation flow shop problem with application in tabu search显示文摘 | Grabowski J Pempera J | 2001 | J of the Operational Research Society2001,52,2: | 1 |
| 14 | Corona above water for systematic study of aqueous phenol degradation 显示文摘 | Grabowski L R Veldhuizen E M van Pemen A J M | 2006 | Plasma Chemistry and Plasma Processing2006,26,1: | 1 |
| 15 | The nature of hydrogen bonding involving the siloxane group显示文摘 | Grabowsky S Beckmann J Luger P | | 0,,07: | 1 |
| 16 | A very fast tabu search algorithm for the permutation flow shop problem with makespan criterion显示文摘 | Grabowski J Wodecki M | 2004 | Computers and Operations Research2004,3,11: | 1 |
| 17 | Intracystic papillary carcinoma : a review of 917 cases 显示文摘 | Grabowski J Salzstein SL Sadler GR | 2008 | Cancer2008,113,5: | 1 |
| 18 | Alternative pre-mRNA splicing and neuronal function显示文摘 | BLACK D L GRABOWSKI P J | 2003 | Prog Mol Subcell Biol2003,31,: | 1 |
| 19 | The Enhancement of X-H…π Hydrogen Bond by Cooperativity Effects Abinitio and QTAIM Calculations显示文摘 | Grabowski S J Leszczynski J | | 0,,2: | 1 |
| 20 | Cognitive dysfunction after total knee arthroplasty 显示文摘 | Rodriguez RA Tellier A Grabowski J | 2005 | Arthroplasty2005,20,6: | 1 |